RESUMEN
OBJECTIVES: Within the context of pharmacy technician's (PT) continuing training (CT), a theoretical instruction in onco-hematology has been developed for PT working in our cytotoxic preparation unit (CPU). The aim of this study is to describe the approach taken, tools used and present knowledge assessment (KA). METHODS: A previous KA has been conducted using quiz available on GERPAC website which listing 36 drugs. Forty-five minutes sessions were conducted. KA was assessing before and after each session and 2 years after. PT appreciation was also evaluated. RESULTS: The previous KA served to targeting gaps and insisted on: indications, mechanism of action and cytotoxic drugs costs. Interactive sessions were led by a pharmacist and concerned about 17 diseases and 3 of the most prescribed cytotoxic drugs: 47 drugs summaries have been written by a pharmacist. The before-after knowledge improvement is significant (P>0.0005) (average [a] before=4.7 vs. a after=9.6). Two years after, this was non-significant but assessment results remain higher than before sessions (a=4.7 vs. 6.8). All PT wish sessions sustainability, 92% reported an adequate comprehension level. CONCLUSION: Lack of time and staff constitute a brake for sustaining and this was also highlighted by other units. Share this experience on a web platform could be interesting. Nevertheless, supports used during sessions should be suitable in conformity with the hospital practice and updated with new therapeutic.
Asunto(s)
Antineoplásicos , Composición de Medicamentos , Neoplasias Hematológicas/tratamiento farmacológico , Técnicos de Farmacia/educación , Costos de los Medicamentos , Evaluación Educacional , Humanos , Farmacéuticos , Servicio de Farmacia en Hospital/organización & administraciónRESUMEN
INTRODUCTION: In 2011, the anticancer preparation unit in a teaching hospital implemented a circuit for batch preparation of anticancer drugs. In this circuit, a manual and a semi-automatic production process coexist. The aim of the study is to describe the circuit in 2016 and to assess the impact of batch preparation in a anticancer preparation unit. MATERIAL AND METHODS: Eligible anticancer drugs for batch preparation satisfy two conditions: solution stability up to 28 days, prescription frequency up to one every two days. Batch worksheets are standardized. The pharmaceutical validation relies on the conformity of microbiological, analytical, gravimetric and visual controls of infusion bags. The duration of manual and semi-automatic batch preparation process and the time availability of an infusion bag were assessed. RESULTS: In 2016, eleven anticancer drugs (33 dosages) were eligible for batch preparation: it represents 22% of total production. In total, 70% was semi-automatic. The mean batch sizes were 27±9 (semi-automatic) and 14±1 (manual). The mean duration of production process was respectively 78min and 113min for semi-automatic and manual batch preparation. The mean time availability of an infusion bag was 32min±17. DISCUSSION AND CONCLUSION: Our process is secure. Batch preparation of anticancer drugs contributes to smooth production and spare nurses from preparing infusion bags outside opening hours of the anticancer preparation unit. Eligible anticancer drugs and batches size change constantly according to the evolution of prescription frequencies and anticancer drugs public tenders.