RESUMEN

Ninety-two strains of Yersinia pestis recovered over a 21-year period were evaluated for susceptibility to traditional and newer antimicrobial agents. In vitro resistance was noted only against rifampin and imipenem (approximately 20% of strains). The most active compounds (MIC at which 90% of the isolates tested are inhibited) against Y. pestis were cefixime, ceftriaxone, trimethoprim-sulfamethoxazole, and trovafloxacin.

Asunto(s)

Antibacterianos/farmacología , Yersinia pestis/efectos de los fármacos , Animales , Cefixima/farmacología , Ceftriaxona/farmacología , Cefalosporinas/farmacología , Humanos , Pruebas de Sensibilidad Microbiana