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Synovial chondromatosis (SC) is a metaplastic disorder characterized by the formation of cartilaginous nodules inside the articular space. SC is uncommon in the temporomandibular joint (TMJ). A few reports suggest a correlation between a traumatic episode and the development of SC. The authors describe the diagnosis, treatment and follow-up of a patient with unilateral SC of the left TMJ in conjunction with bony resorption on the mandibular condyle and a clear traumatic etiology. They review and comment on previous reports in the literature.

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OBJECTIVES: 1) To identify the profile of the cases requested for autopsy; 2) to analyze the clinocopathological discordance; 3) to investigate predictive factors for unsuspected clinically relevant diagnoses. PATIENTS AND METHOD: All autopsies performed between January 1999 and December 2005 in a tertiary neonatal intensive care unit, were retrospectively reviewed. Clinicopathological concordance was assessed independently by two neonatologists and two pathologists, according to a modification of the Goldman classification. A comparison was made between newborns who had an autopsy performed and those who did not and predictive factors for unsuspected findings were investigated. RESULTS: During the study period, there were 309 deaths, and autopsies were performed in 128 (41.4 %) of these cases. Autopsies were more common in newborns who had gestational age > 36 weeks (p < 0.001), birthweight > 1500 g (p < 0.001) and congenital defects (p < 0.007). However, the probability that the autopsy was granted decreased with increasing death age (p < 0.016). Unsuspected diagnoses were observed in 49.2 % of the autopsies, being a major finding in 21.1 % of the cases. A clinicopathological discordance involving the prognosis was found in four cases (3.1 %). Relevant unsuspected findings could not be predicted from the ante-mortem clinical diagnosis, gestational age, birthweight, sex, and death age. CONCLUSION: The autopsy remains the "gold standard" method to reveal major and unsuspected diagnoses and there is no substitute for it. Postmortem examination should be requested systematically in every neonatal death. However, several factors such as gestational age, birthweight, presence of congenital defects and death age, influence the likelihood of autopsy being granted.

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Introducción y objetivo: el tumor phyllodes es una tumoraciónpoco frecuente de la mama, de comportamiento clínicoimprevisible y cuyo tratamiento es aún objeto de controversia.Presentamos una revisión de 35 casos diagnosticados y tratadosen nuestro centro a lo largo de 10 años, así como una revisiónde los datos publicados en la literatura.Pacientes y métodos: estudio retrospectivo, descriptivo, de35 pacientes portadoras de esta neoplasia estudiadas en la“Unidad de Oncología y Patología Mamaria” (HH.UU. Virgendel Rocío. Sevilla) entre enero de 1998 y enero de 2007.Resultados: la edad al momento del diagnóstico fue de45,02 ± 15 años. El tiempo medio de duración de la sintomatologíafue de 7,8 meses. La forma de presentación en todoslos casos fue la aparición de una tumoración, que en el 11%casos tuvo un crecimiento rápido. La mayoría se localizó enlos cuadrantes supero-externos y el tamaño osciló entre los 2y 20 cm. Las pruebas de imagen orientaron el diagnóstico enel 20% casos; la PAAF/Tru-cut fue positiva en 7 pacientes.De los 35 casos, 54,5% fueron benignos, 27,3% malignos y18,2% borderline. En el 68,6% de las pacientes se realizó tumorectomíaamplia; en cinco pacientes se realizó mastectomíay en un caso se indicó radioterapia adyuvante. Sólo 3 pacientespresentaron recidivas loco-regionales. 2 pacientes evolucionaroncon metástasis a distancia.Conclusiones: la resección con amplios márgenes de seguridades el tratamiento de elección y principal factor que condicionala probabilidad de recidiva local y a distancia de los tumoresphyllodes(AU)

Introduction and objective: the phyllodes tumour is anuncommon breast lesion, with an unpredictable clinical behaviour,which treatment is exposed to controversy. We analyzethe results of 35 patients diagnosed and treatment in ourcenter during 10 years, and also review the dates report onthe literature.Patients and methods: we retrospectively reviewed 35 patientshaving phyllodes tumour, seen at “Unidad de Oncologíay Patología Mamaria” (HH.UU. Virgen del Rocío.Sevilla) between January 1998 and January 2007.Results: the mean age at diagnosis was 45.02 ± 15 years.The mean follow-up was 7.8 months. The appearance of amass was the way of presentation in all cases; in 11% patientsthe tumour’s growth was fast. Tumours predominated on theupper-outer quadrant and the range size was 2-20 cm. Imagingfinding were helpful for diagnosis in 20% cases.PAAF/Tru-cut were positive in 7 patients. Tumours were classifiedas benign in 54.5% cases, malignant (27.3%) and borderline(18.2%). Wide tumorectomy was performed in 68.6%of cases. 5 patients underwent mastectomy, and another onereceived adjuvant external radiation therapy. Only 3 patientshad a recurrence and two had metastases.Conclusions: wide excision with a clear margin may be thepreferable initial therapy. Loco-regional and general spreaddepends on margin surgery(AU)

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