RESUMEN

The present report describes the detection of co-circulation of all the four dengue serotypes along with rarely detected dengue viruses (DENVs)-4 for the first time in Odisha. One hundred and forty-eight blood samples were tested for dengue NS1 antigen ELISA and IgM antibody (Ab), and twenty early samples were subjected for type-specific multiplex reverse transcription-polymerase chain reaction (RT-PCR). Twenty-three samples found positive for dengue NS1 and/or IgM Ab; five were positive by RT-PCR. DENV-4 was detected in one sample, DENV-2 in two and 2 were co-infected with DENV-1 and 3. Co-circulation of all four dengue serotypes in Eastern India emphasises the need of molecular monitoring of circulating DENV serotypes.

Asunto(s)

Virus del Dengue/clasificación , Virus del Dengue/aislamiento & purificación , Dengue/epidemiología , Dengue/virología , Serogrupo , Adolescente , Adulto , Anciano , Anticuerpos Antivirales/sangre , Antígenos Virales/sangre , Virus del Dengue/genética , Ensayo de Inmunoadsorción Enzimática , Femenino , Técnicas de Genotipaje , Humanos , Inmunoglobulina M/sangre , India/epidemiología , Masculino , Persona de Mediana Edad , Epidemiología Molecular , Reacción en Cadena de la Polimerasa Multiplex , Reacción en Cadena de la Polimerasa de Transcriptasa Inversa , Proteínas no Estructurales Virales/sangre , Adulto Joven