RESUMEN
Acquired digital fibrokeratoma (ADF) is an uncommon benign tumor of fibrous tissue that presents as smooth, dome-shaped or fingerlike, flesh-colored papules that are mostly located on the distal extremities. As it can easily be misdiagnosed for other common benign lesions such as viral warts, which usually are not subject to routine histopathologic examination, it might be underreported. We report 13 patients with ADF diagnosed in our clinic in the past 4 1/2 years.
Asunto(s)
Fibroma/patología , Dedos , Queratosis/patología , Neoplasias Cutáneas/patología , Adolescente , Adulto , Anciano , Niño , Femenino , Fibrosis , Dermatosis de la Mano/patología , Humanos , Masculino , Persona de Mediana EdadRESUMEN
BACKGROUND: Prurigo pigmentosa (PP) is a rare inflammatory dermatosis of unknown etiology. It is characterized by erythematous papules of the trunk that resolve leaving a reticulate hyperpigmentation. The original report from Japan in 1971 was followed by new cases, mostly of Japanese origin. METHODS: We scrutinized PP cases diagnosed in our clinic and reviewed the English, German, French, and Turkish language literature. RESULTS: We report six additional Turkish patients. We found more than 40 cases reported from various countries outside Japan. The patients had different racial origins. The number of Turkish patients reported in recent years is higher than the number of other non-Japanese patients reported. CONCLUSIONS: The disease is not uncommon in the Turkish population. It may be underestimated in other countries with Caucasian populations. Therapeutic results with tetracycline and doxycycline was successful in our patients.
Asunto(s)
Hiperpigmentación/patología , Prurito/patología , Adolescente , Adulto , Femenino , Humanos , TurquíaRESUMEN
BACKGROUND: Nevus sebaceus (NS) is a congenital hamartomatous lesion, usually involving the scalp or the face. Various benign and malignant neoplasms can develop in association with NS, the most common being trichoblastoma, syringocystadenoma papilliferum, viral warts and basal cell carcinoma (BCC). PATIENTS AND METHODS: We retrospectively examined the clinical and histopathological records of 15 NS cases with an associated tumor which were diagnosed between 1996 and 2004. RESULTS: All cases were adults and 3 of them had more than one tumor. Six cases had BCC, which is a higher incidence of malignant tumor association with NS, than that reported in last years. Trichoblastoma was observed in 3 cases and was the most common benign tumor in our series. Filiform, hyperkeratotic, pigmented, pedunculated and/or eroded papulonodular changes were major clinical signs of secondary tumors on NS in our series. CONCLUSION: Clinical features are not sufficient enough to make an exact diagnosis of benign or malignant secondary tumors. Though prophylactic excision for NS is done less in last years, especially adult patients should closely be followed for any new changes evoking tumor development on this congenital lesion.