RESUMEN
A chloroform extract of the roots of the Egyptian Salvia lanigera Poir. afforded two new orthoquinones, lanigerone (8-hydroxy-3-isopropyl-7-methyl-1,2-naphthoquinone) and salvigerone (methyl 1,10-seco-5(10),6,8,13-abietatetraene-11,12-dion-1-oate) together with two known diterpenoids, arucadiol and pisiferal. Structural assignments of the new compounds were based on spectroscopic methods (UV, IR, MS, ID- and 2D-NMR).
RESUMEN
Roots of Salvia lanigera Poir. yielded a new icetexane [10,12-dihydroxy-9(10-->20)-abeo-8,11,13-abietatriene], named lanigerol, which had activity (MIC 1 mg/ml) against Gram-positive bacteria.
Asunto(s)
Abietanos , Antibacterianos/farmacología , Diterpenos/farmacología , Plantas/química , Antibacterianos/química , Diterpenos/química , Bacterias Grampositivas/efectos de los fármacos , Espectroscopía de Resonancia Magnética , Espectrometría de Masas/métodosRESUMEN
The ethereal extract of AJUGA IVA (L.) S CHREB. roots, yielded 4 ecdysones. Three were proved to be cyasterone, makisterone A and ecdysterone, by using UV, IR, MS spectral methods and comparison with standard samples. Spectral data indicate that the fourth ecdysone is similar to cyasterone but having an additional hydroxy group in the side-chain. The chromatographic pattern of ecdysone content in roots, stems and leaves is presented as well as a rapid and simple Semiquantitative method for their estimation. The roots had the highest total content (0.381%).