RESUMEN

Among the 51,823 postmenopausal women in the Swedish Mammography Cohort, we investigated breast cancer risk in relation to the FFQ-based estimated lignan intake by oestrogen receptor (ER) and progesterone receptor (PR) subtypes. A significant 17% risk reduction for breast cancer overall in the high lignan quartile was observed, especially among PMH user (P interaction<0.010), but no heterogeneity across ER/PR subtypes.

Asunto(s)

Neoplasias de la Mama/epidemiología , Dieta , Lignanos , Neoplasias Hormono-Dependientes/epidemiología , Posmenopausia , Receptores de Estrógenos/metabolismo , Estudios de Cohortes , Femenino , Terapia de Reemplazo de Hormonas , Humanos , Persona de Mediana Edad , Estudios Prospectivos , Receptores de Progesterona/metabolismo , Factores de Riesgo , Suecia