RESUMEN
OBJECTIVE: Assessment of antibacterial properties of a new intracanal paste based on calcium hydroxocuprate (CHC) and silver nanoparticles hydrosol for passive root impregnation. MATERIAL AND METHODS: The study included 55 teeth with 69 root canals belonging patients with chronic apical periodontitis. The main group, including 44 root canals, was filled with a new paste based on CHC and silver nanoparticles for 7 days after preparation and irrigation. In the control group, 25 root canals were sealed with an aqueous paste of calcium hydroxide for 14 days. The presence of the endodontic microorganisms was evaluated by real-time PCR. RESULTS AND DISCUSSION: Further analysis showed that the amount of the DNA, common for P. gingivalis, T. forsythia and T. denticola, after treatment was less in the main group, where the new paste was applied. These results were significant at the p=0.05 level (p=0.005, p=0.006, p=0.003 according to each mentioned bacterial sample). No significant differences were found between the groups in the number of genome equivalents specific for P. intermedia and F. nucleatum (p=0.543, p=0.554). CONCLUSION: These findings suggest that the new method of passive root impregnation with the CHC and silver nanoparticles paste may be an effective method for the treatment of chronical apical periodontitis.
Asunto(s)
Nanopartículas del Metal , Periodontitis Periapical , Humanos , Reacción en Cadena en Tiempo Real de la Polimerasa , Nanopartículas del Metal/uso terapéutico , Plata/farmacología , Calcio , Antibacterianos/farmacología , Antibacterianos/uso terapéutico , Periodontitis Periapical/tratamiento farmacológico , Raíz del Diente , DentinaRESUMEN
THE AIM: Was to study the promising areas for using nanotechnologies in dentistry, existing methods of diagnostics, treatment and prevention of the dental diseases based on the properties of nanoparticles, to review the scientific literature devoted to this problem. In this literature review we use 86 sources: 1 Russian and 85 foreign articles. Analyzed articles were published within the last 5 years. The literature review summarizes and presents up-to-date methods of diagnosing, treating, and preventing dental disease that use nanotechnologies. Development and implementation of nanotechnological treatment are a promising direction for modern dentistry.
Asunto(s)
Nanoestructuras , Odontología , Humanos , Federación de RusiaRESUMEN
The aim was to investigate the acid-base balance in the mouth and assess the risk of dental disease in practically healthy persons depending on the habitual diet. MATERIALS AND METHODS: The study involved 162 people, divided into three groups: with a mixed diet, with protein foods of animal origin and vegetarians. There were studied the pH value of oral fluid, dental, lingual plaque at stimulation with sucrose and urea. RESULTS: In individuals, characterized by the habitual diet, there are statistically significant persistent changes in acid-base balance in the mouth, which provoke an increased risk of developing dental diseases. At normal mixed diet there is moving the acid-base balance towards weak acidosis that in the presence of other predisposing factors can lead to the risk of devel- opment of dental caries. There is a displacement of acid-base balance in the oral cavity to the alkaline side in case the long predominant consumption of protein foods of animal origin, that is dangerous in terms of formation of hard dental deposits and consequently of the development of inflammatory periodontal diseases. In vegetarians, there is a persistent shift of acid-alkaline balance in the mouth in the direction of acidosis, which is a risk factor for development of dental caries.