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1.
Rev Mal Respir ; 40(7): 604-622, 2023 Sep.
Artículo en Francés | MEDLINE | ID: mdl-37357041

RESUMEN

INTRODUCTION: Long COVID refers to persistent symptoms, lasting more than 4 weeks after acute SARS-CoV-2 infection, even though the infection itself has been successfully controlled and remedied. Patient complaints are diverse, and the underlying physiopathological mechanisms are not well understood. Dyspnea and muscle fatigue are among the most commonly reported symptoms. STATE OF THE ART: Cardiopulmonary exercise test (CPET) has been recognized as a useful tool in investigation of unexplained dyspnea. In patients with chronic lung disease, pulmonary rehabilitation is a program designed to counteract dyspnea, to increase exercise capacity and to improve quality of life. PERSPECTIVES: Publications on CPET and pulmonary rehabilitation are needed in order to deepen comprehension and enhance management of long-COVID-19. CONCLUSIONS: CPET reports have shown that symptoms persisting in the aftermath of acute SARS-CoV-2 infection may be related to deconditioning, a common occurrence after ICU stay, to cardiac dysautonomia subsequent to critical infections and, finally, to dysfunctional breathing subsequent to mild infections. These findings justify pulmonary rehabilitation, which has proven to be effective regardless of the severity of the initial infection, not only immediately after hospital discharge, but also at later points in time.


Asunto(s)
COVID-19 , Humanos , Prueba de Esfuerzo , Síndrome Post Agudo de COVID-19 , Calidad de Vida , SARS-CoV-2 , Disnea/diagnóstico , Disnea/etiología
2.
Sci Justice ; 59(1): 58-66, 2019 01.
Artículo en Inglés | MEDLINE | ID: mdl-30654969

RESUMEN

The present study aimed at providing data to assess the secondary transfer of organic gunshot residues (OGSR). Three scenarios were evaluated in controlled conditions, namely displacing a firearm from point A to point B, a simple handshake and an arrest involving handcuffing on the ground. Specimens were collected from the firearm, the hands of the shooter and the non-shooter undergoing the secondary transfer in order to compare the amounts detected. Secondary transfer was observed for the three scenarios, but to a different extent. It was found that displacing a firearm resulted in secondary transfer in <50% of the experiments. The firearm also had an influence, as contrary to the pistol, no secondary OGSR were detected using the revolver. Shaking the hand of the shooter also transferred OGSR to the non-shooter's hand. In that case, the amount of OGSR was generally higher on the shooter than on the non-shooter. Finally, the largest secondary transfer was observed after the arrest with handcuffing with positive results in all cases using the pistol. In that scenario, the amounts on the shooter and the non-shooter were in the same range. This study highlights that the secondary transfer must be taken into account in the interpretation of OGSR. Indeed, an individual's hands might be contaminated by handling a firearm or having physical contact with a shooter.


Asunto(s)
Armas de Fuego , Balística Forense/métodos , Mano , Manejo de Especímenes , Cromatografía Líquida de Alta Presión , Humanos , Aplicación de la Ley/métodos , Piel/química , Espectrometría de Masa por Ionización de Electrospray
3.
Forensic Sci Int ; 277: 241-251, 2017 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-28688314

RESUMEN

The main goal of the present study was to determine the amounts and distribution of organic gunshot residues (OGSR) on the shooter's upper body and clothing after discharging a pistol. A preliminary study was also performed to evaluate the prevalence of OGSR in the general population as well as in a police laboratory environment. In the transfer study, results indicated that OGSR are not only transferred to the hand of the shooter, but also to other parts of the upper body. Thus, wrists and forearms also represent interesting targets as they are washed less frequently than hands. Samples from the face and hair of the shooters resulted in no OGSR detection just after firing. It was also observed that the concentrations recovered from clothing are generally higher compared to the same skin area. Prevalence in both general (n=27) and police populations (n=25) was low. No OGSR was detected in the samples from the general population and only two samples from the police population were found positive.

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