RESUMEN
BACKGROUND: Three types of plasma are widely available for transfusion. Two plasma components, FFP donor retested (FFP-DR), and solvent/detergent-treated plasma (SDP), are now considered to be safer from infectious complications than FFP. STUDY DESIGN AND METHODS: A large regional blood center attempted to provide FFP-DR exclusively to all its 42 hospitals. Significant planning, increases in computer capabilities, and expansion of component storage areas were completed before initiation of this program. RESULTS: During the first 6 months of the FFP-DR program, the blood center was not able to supply the entire region exclusively with FFP-DR. Consequently, SDP was utilized to supplement the program and to successfully and completely convert the region's 42 hospitals to the use of safer plasma. CONCLUSION: Two new plasma components were utilized to completely convert a blood service region to the use of safer plasma.
Asunto(s)
Bancos de Sangre/organización & administración , Plasma , Donantes de Sangre , Transfusión Sanguínea/normas , Seguridad de Productos para el Consumidor/normas , Detergentes/farmacología , Humanos , Indiana , Plasma/efectos de los fármacosRESUMEN
Therapeutic apheresis has gained tremendous popularity worldwide in the last 2 decades. Emergency procedures can be life saving but should be undertaken for limited indications. Our emergency indications and experiences since the 1970s are critically described.
Asunto(s)
Eliminación de Componentes Sanguíneos , Tratamiento de Urgencia , Enfermedades Hematológicas/terapia , Enfermedad por Anticuerpos Antimembrana Basal Glomerular/terapia , Humanos , Miastenia Gravis/terapia , Polirradiculoneuropatía/terapiaRESUMEN
The Kasabach-Merritt Syndrome describes thrombocytopenia occurring in patients with giant hemangiomata. The resultant thrombocytopenia may be profound and occasionally even life-threatening. An 11-month-old infant with prolonged thrombocytopenia whose course was complicated by recurrent hemorrhaging requiring intense platelet transfusions is reported. During her 19-month hospitalization she received 6,622 platelet concentrates. This represents the most extensive platelet support ever given to an infant with this syndrome.