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1.
Sci Adv ; 6(35): eabc2938, 2020 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-32923650

RESUMEN

Deep CO2 emissions characterize many nonvolcanic, seismically active regions worldwide, and the involvement of deep CO2 in the earthquake cycle is now generally recognized. However, no long-time records of such emissions have been published, and the temporal relations between earthquake occurrence and tectonic CO2 release remain enigmatic. Here, we report a 10-year record (2009-2018) of tectonic CO2 flux in the Apennines (Italy) during intense seismicity. The gas emission correlates with the evolution of the seismic sequences: Peaks in the deep CO2 flux are observed in periods of high seismicity and decays as the energy and number of earthquakes decrease. We propose that the evolution of seismicity is modulated by the ascent of CO2 accumulated in crustal reservoirs and originating from the melting of subducted carbonates. This large-scale, continuous process of CO2 production favors the formation of overpressurized CO2-rich reservoirs potentially able to trigger earthquakes at crustal depth.

2.
Sci Rep ; 7(1): 6757, 2017 07 28.
Artículo en Inglés | MEDLINE | ID: mdl-28754925

RESUMEN

In volcanoes with active hydrothermal systems, diffuse CO2 degassing may constitute the primary mode of volcanic degassing. The monitoring of CO2 emissions can provide important clues in understanding the evolution of volcanic activity especially at calderas where the interpretation of unrest signals is often complex. Here, we report eighteen years of CO2 fluxes from the soil at Solfatara of Pozzuoli, located in the restless Campi Flegrei caldera. The entire dataset, one of the largest of diffuse CO2 degassing ever produced, is made available for the scientific community. We show that, from 2003 to 2016, the area releasing deep-sourced CO2 tripled its extent. This expansion was accompanied by an increase of the background CO2 flux, over most of the surveyed area (1.4 km2), with increased contributions from non-biogenic source. Concurrently, the amount of diffusively released CO2 increased up to values typical of persistently degassing active volcanoes (up to 3000 t d-1). These variations are consistent with the increase in the flux of magmatic fluids injected into the hydrothermal system, which cause pressure increase and, in turn, condensation within the vapor plume feeding the Solfatara emission.

6.
J Neurosurg ; 83(5): 897-902, 1995 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-7472561

RESUMEN

Hydroxyethylmethacrylate (HEMA) hydrogels were investigated for their suitability as a dural prosthesis. Poly-HEMA has many characteristics required for an artificial dural substitute: it is durable, flexible, easily prepared, inexpensive, easily sterilized and handled, easily shaped, and known to be chemically inert and nontoxic. Sheets made of plain HEMA were evaluated as dural substitutes in rats and rabbits after either craniotomy or laminectomy with durectomy. Histological evaluations of the prostheses and the underlying tissues were undertaken at various time points from 2 to 9 weeks postoperatively. There was minimal tissue response to the implanted HEMA gel in contrast to marked thickening of the overlying leptomeninges and cortical herniation in the control animals. It is concluded that HEMA gels fulfill the essential criteria for an effective dural substitute.


Asunto(s)
Materiales Biocompatibles , Duramadre/cirugía , Polihidroxietil Metacrilato , Prótesis e Implantes , Animales , Encéfalo/patología , Duramadre/patología , Conejos , Ratas , Médula Espinal/patología
7.
Neurosurgery ; 23(3): 300-6, 1988 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-3226509

RESUMEN

Posterior stabilization of cervical spine fractures and subluxations with metal plates and screws is commonly used in Europe, but has rarely been employed by neurosurgeons in North America, where stabilization has usually been achieved with wires supplemented by bone grafts or acrylic. The limitations of the more commonly used stabilization techniques include the failure to achieve rotational stability, the necessity for intact laminae, and the requirement for bone grafting. We therefore examined the efficacy of posterior cervical plating in 19 patients who had posttraumatic instability of the cervical spine between C3 and C7 without residual spinal cord compression and 1 patient who had a subluxation as a result of osteomyelitis. Two patients had no neurological deficit, 4 had partial deficits, and 14 had no neurological function below the level of injury. Operation was performed after patients were medically stable and maximal reduction of fractures was achieved (usually within 48 hours). The plates are made of vitallium and contain two or three holes 13 mm apart through which 16-mm screws are placed bilaterally into the center of the articular masses of two or three adjacent vertebrae to stabilize one or two motion segments. Bone grafting is not performed. Patients are mobilized on the day after operation in a Philadelphia collar, which is worn for 3 months. Fourteen patients had stabilization of one motion segment and 6 had stabilization over two motion segments. The mean follow-up is 9.2 months. In a single patient with ankylosing spondylitis, plate fixation failed when screws pulled out. No patient experienced neurological deterioration as a result of the operative procedure.(ABSTRACT TRUNCATED AT 250 WORDS)


Asunto(s)
Fijación Interna de Fracturas/métodos , Dispositivos de Fijación Ortopédica , Traumatismos Vertebrales/cirugía , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Placas Óseas , Tornillos Óseos , Vértebras Cervicales , Femenino , Fijación Interna de Fracturas/instrumentación , Humanos , Masculino , Persona de Mediana Edad , Radiografía , Traumatismos Vertebrales/diagnóstico por imagen
8.
Minerva Med ; 73(5): 187-90, 1982 Feb 11.
Artículo en Italiano | MEDLINE | ID: mdl-7038553

RESUMEN

200 mg UDPG or placebo respectively were administered after an observation period of 1 week to two randomly constructed groups of patients aged 15-35 yr with acute viral hepatitis but no prior history of disease. In the treated patients, mean decreases were most marked and most rapid in the case of SGOT, SGPT, alkaline phosphatase and total bilirubinaemia. These results offer good reason for supposing that UDPG can be usefully employed in the management of acute viral hepatitis.


Asunto(s)
Hepatitis Viral Humana/tratamiento farmacológico , Uridina Difosfato Glucosa/uso terapéutico , Azúcares de Uridina Difosfato/uso terapéutico , Enfermedad Aguda , Adolescente , Adulto , Fosfatasa Alcalina/metabolismo , Bilirrubina/sangre , Ensayos Clínicos como Asunto , Femenino , Humanos , Masculino , Transaminasas/metabolismo
9.
J Toxicol Environ Health ; 3(5-6): 797-809, 1977 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-599579

RESUMEN

A program for a small digital computer was developed to calculate the median lethal dose (LD50) and its errors. The algorithm employed in the program was based on a method described by Bliss. Modifications introduced by Finney are also discussed. The results indicate a high degree of accuracy compared with calculations performed by Bliss. The accuracy and speed of calculation exceeded those possible with simplified and graphic methods. The data and results for four toxic compounds are presented.


Asunto(s)
Computadores , Dosificación Letal Mediana , Animales , Relación Dosis-Respuesta a Droga , Estudios de Evaluación como Asunto , Matemática , Métodos , Ratones , Ratones Endogámicos C3H , Ratones Endogámicos C57BL , Compuestos Nitrosos/toxicidad
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