RESUMEN
Arritmogenic right ventricular dysplasia (ARVD) is characterized by the gradual replacement of myocytes by adipose and fibrous tissue. Described in 1977, is considered a potentially lethal cause of cardiac disease poorly understood. This disorder usually involves the right ventricle and has been associated with arrthymia, heart failure, and sudden death. In this paper, we report a case of a 25-year-old patient with syncope associated with ventricular extrasystoles. A magnetic resonance imaging was performed and showed findings that support ARVD diagnose.
Asunto(s)
Displasia Ventricular Derecha Arritmogénica/diagnóstico , Adulto , Síndrome de Brugada/diagnóstico , Diagnóstico Diferencial , Humanos , Imagen por Resonancia Magnética/normas , MasculinoRESUMEN
A displasia arritmogênica do ventrículo direito (DAVD) é caracterizada pela substituição dos miócitos por tecido fibrogorduroso. Descrita em 1977, é considerada uma doença cardíaca potencialmente letal ainda pouco entendida. Afeta primariamente o ventrículo direito e tem sido associada a arritmias, insuficiência cardíaca e morte súbita. O objetivo deste artigo é descrever o caso clínico de um paciente de 25 anos com síncope associada a extra-sístoles ventriculares e achados de ressonância magnética do coração compatíveis com DAVD.
Arritmogenic right ventricular dysplasia (ARVD) is characterized by the gradual replacement of myocytes by adipose and fibrous tissue. Described in 1977, is considered a potentially lethal cause of cardiac disease poorly understood. This disorder usually involves the right ventricle and has been associated with arrthymia, heart failure, and sudden death. In this paper, we report a case of a 25-years-old patient with syncope associated with ventricular extrasystoles. A magnetic resonance imaging was performed and showed findings that support ARVD diagnose.
Asunto(s)
Adulto , Humanos , Masculino , Displasia Ventricular Derecha Arritmogénica/diagnóstico , Síndrome de Brugada/diagnóstico , Diagnóstico Diferencial , Imagen por Resonancia Magnética/normasRESUMEN
BACKGROUND: Information on the clinical progression, in the long term, of patients submitted to mechanical reperfusion is scarce. OBJECTIVE: The objective of this study is to describe the long-term clinical progression of patients submitted to primary stenting. METHODS: Between January 1998 and December 2003 we studied a non-concurring cohort with a fixed population of 202 patients (mean age = 61.2 +/- 7.7 years; 74.7% males and 25.3% females) submitted to primary stenting. All the patients were followed up clinically and we assessed the occurrence of deaths, acute myocardial infarction (AMI), cerebral vascular accident (CVA) and surgical or percutaneous myocardial revascularization (MR). Kaplan-Meier survival curves were built for the following events: death, deaths/AMI, deaths/AMI/CVA and major cardiovascular events (MCE). RESULTS: In 91.5% of the patients the procedure was successful. During hospital stay, mortality was 3.4%; reinfarction was 0.9%; CVA was 1.8%; and urgent MR was 1.4%. Clinical follow-up varied from 29 to 100 months (mean = 58.7 +/- 19.7 months). Death-free survival was estimated at 93.6%; death/AMI-free survival at 89.6%; death-AMI/CVA-free survival at 87.1%; and MCE-free survival at 71.3% CONCLUSION: Primary stenting presented excellent results during hospital stay. Very late clinical follow-up demonstrated that these good initial results have held up.
Asunto(s)
Angioplastia Coronaria con Balón , Infarto del Miocardio/mortalidad , Stents , Enfermedad Aguda , Estudios de Cohortes , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Infarto del Miocardio/terapia , Revascularización Miocárdica/estadística & datos numéricos , Accidente Cerebrovascular/epidemiología , Análisis de Supervivencia , Factores de Tiempo , Resultado del TratamientoRESUMEN
FUNDAMENTO: Informações sobre a evolução clínica, em longo período, de pacientes submetidos a reperfusão mecânica são escassas. OBJETIVO: O objetivo deste estudo é descrever a evolução clínica a longo prazo de pacientes submetidos a implante de stent primário. MÉTODOS: Entre janeiro de 1998 e dezembro de 2003, foi estudada uma coorte não concorrente fixa de 202 pacientes (média de idade = 61,2 ± 7,7 anos; 74,7 por cento homens e 25,3 por cento mulheres) submetidos a implante de stent primário. Foi realizado seguimento clínico de todos os pacientes e avaliada a ocorrência de óbitos, infarto agudo do miocárdio (IAM), acidente vascular encefálico (AVE) e revascularização do miocárdio (RM) cirúrgica ou percutânea. Foram construídas curvas de sobrevida de Kaplan-Meier para os eventos óbito, óbitos/IAM, óbitos/IAM/AVE e cardiovasculares maiores (ECVM). RESULTADOS: Em 91,5 por cento dos pacientes o procedimento foi bem-sucedido. Na fase hospitalar, a mortalidade foi de 3,4 por cento; o reinfarto, de 0,9 por cento; o AVE, de 1,8 por cento; e a RM de urgência, de 1,4 por cento. O seguimento clínico variou de 29 a 100 meses (média = 58,7 ± 19,7 meses). A estimativa da sobrevida livre de óbito foi de 93,6 por cento; a da sobrevida livre de óbito/IAM, de 89,6 por cento; a da sobrevida livre de óbito/IAM/AVE, de 87,1 por cento; e a da sobrevida livre de ECVM, de 71,3 por cento. CONCLUSÃO: O implante de stent primário apresentou excelentes resultados na fase hospitalar. O seguimento clínico muito tardio demonstrou que esses bons resultados iniciais foram mantidos.
BACKGROUND: Information on the clinical progression, in the long term, of patients submitted to mechanical reperfusion is scarce. OBJECTIVE: The objective of this study is to describe the long-term clinical progression of patients submitted to primary stenting. METHODS: Between January 1998 and December 2003 we studied a non-concurring cohort with a fixed population of 202 patients (mean age = 61.2 ± 7.7 years; 74.7 percent males and 25.3 percent females) submitted to primary stenting. All the patients were followed up clinically and we assessed the occurrence of deaths, acute myocardial infarction (AMI), cerebral vascular accident (CVA) and surgical or percutaneous myocardial revascularization (MR). Kaplan-Meier survival curves were built for the following events: death, deaths/AMI, deaths/AMI/CVA and major cardiovascular events (MCE). RESULTS: In 91.5 percent of the patients the procedure was successful. During hospital stay, mortality was 3.4 percent; reinfarction was 0.9 percent; CVA was 1.8 percent; and urgent MR was 1.4 percent. Clinical follow-up varied from 29 to 100 months (mean = 58.7 ± 19.7 months). Death-free survival was estimated at 93.6 percent; death/AMI-free survival at 89.6 percent; death-AMI/CVA-free survival at 87.1 percent; and MCE-free survival at 71.3 percent CONCLUSION: Primary stenting presented excellent results during hospital stay. Very late clinical follow-up demonstrated that these good initial results have held up.