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RESUMEN El papiloma oncocítico (PO) es una neoplasia rara de la cavidad nasal y los senos paranasales y es el subtipo histológico menos frecuente del papiloma rinosinusal. Al igual que el papiloma invertido (PI), se lo considera un tumor benigno, pero su comportamiento biológico no lo es tanto por su crecimiento local agresivo, su tasa alta de recurrencia y el riesgo de transformación maligna con asociación a carcinoma. El tratamiento de elección es la resección endoscópica. Se ha usado exitosamente la radioterapia para el tratamiento de los PI extensos, pero no se conocen informes documentados de su uso en pacientes con PO avanzado o con extensión extrasinusal y sin malignización asociada. Se presenta un caso de PO unilateral izquierdo con enfermedad extensa que comprometía la pared nasal lateral y los senos maxilar, etmoidal y frontal del mismo lado, tratado con radioterapia en arcos de volumen modulado.

SUMMARY Oncocytic papiloma (OP) is a rare neoplasm of the nasal cavity and paranasal sinuses. It is the least common histological subtype of sinonasal papilloma. OP is regarded as a benign tumor like inverted papilloma (IP), but its biological behavior is not so benign due to its aggressive local growth, the high rate of recurrences and the risk of malignant transformation with associated carcinoma. Endoscopic resection is the treatment of choice for OP. No relevant reports on the use of radiotherapy are known in patients with OP with advanced disease or extrasinonasal extension without associated malignancy, although its application in advanced IP has been successfull. We report a case of unilateral left OP with advanced disease that involved lateral nasal wall, maxillary, ethmoidal and frontal sinus on the same side, treated with volumetric modulated arc radiotherapy.

RESUMO O Papiloma Oncocítico (PO) é uma neoplasia rara da cavidade nasal e os Seios Parinasais menos comum e representa o subtipo histológicos menos frequente dos Papilomas Nasossinusais (PNS). Assim como o Papiloma Invertido (PI), o PO é considerado um tumor benigno, mas o seu comportamento biológico não é tão benigno devido a seu crescimento local agressivo, a sua elevada taxa de recorrência e o risco potencial de transformação maligna com carcinoma associado. A ressecção endoscópica é o tratamento de preferência do PO. Em pacientes com doença avançada ou extensão extrassinusal sem malignidade associada, não há relatórios relevantes do uso de radioterapia (RT), embora a sua aplicação no caso dos PI avançados, em que tem sido utilizado com sucesso. Um caso de PO unilateral é apresentado com doença extensa que comprometeu a parede lateral nasal e os seios maxilar, etmoidal e frontal do mesmo lado, que foi tratado com sucesso com cirurgia endoscópica e radioterapia em arco volumetricamente modulada (RAVM).

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Immediate neonatal surgery (INS) has the purpose of achieving surgical treatment of a congenital malformation in a newborn within the first few minutes after delivery. Since 1993, we have invited 15 pregnant women with sonographic diagnosis of fetal abdominal wall defect to participate in INS. All were treated by means of elective (eight cases) or emergent (seven cases) cesarean section between 33 and 38 gestational weeks. The neonates were immediately operated on the procedure beginning between 17 and 35 min after delivery. Eleven neonates had gastroschisis and primary closure was accomplished in five cases with application of auxiliary plastic patch (45.5) and in four cases with use of native tissues only (36.4); nine neonates survived (81.8), and were able to be fed by mouth at 14 +/- 4.5 days. Four had omphalocele, and in three primary closure and feeding by mouth before 1 week was attained; the fourth neonate died because of coexisting malformations. The present series, even if small, is useful to affirm the safety of a procedure such as INS for both mother and child; it may contribute to improve the results of treatment of fetuses with abdominal wall defects.

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Immediate neonatal surgery (INS) has the purpose of achieving surgical treatment of a congenital malformation in a newborn within the first few minutes after delivery. Since 1993, we have invited 15 pregnant women with sonographic diagnosis of fetal abdominal wall defect to participate in INS. All were treated by means of elective (eight cases) or emergent (seven cases) cesarean section between 33 and 38 gestational weeks. The neonates were immediately operated on the procedure beginning between 17 and 35 min after delivery. Eleven neonates had gastroschisis and primary closure was accomplished in five cases with application of auxiliary plastic patch (45.5%) and in four cases with use of native tissues only (36.4%); nine neonates survived (81.8%), and were able to be fed by mouth at 14 +/- 4.5 days. Four had omphalocele, and in three primary closure and feeding by mouth before 1 week was attained; the fourth neonate died because of coexisting malformations. The present series, even if small, is useful to affirm the safety of a procedure such as INS for both mother and child; it may contribute to improve the results of treatment of fetuses with abdominal wall defects.

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