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Arch Androl ; 52(2): 87-90, 2006.
Artículo en Inglés | MEDLINE | ID: mdl-16443583

RESUMEN

In order to assess the frequency of chromosomal abnormalities in azoospermic males from western Mexico, we carried out a retrospective study in 227 patients. Forty-three (18.9%) cases with an abnormal karyotype were found. The most frequent chromosomal anomaly was 47,XXY, which was identified in 35 subjects (15.4%). In six cases (2.6%), structural aberrations were detected: two Robertsonian translocations [(45,XY,t(13;22)(p11;p11) and (45,XY,t(13;15)(p11;p11)], a Y;autosome translocation [46,XY,der(15)t(Y;15)(q12;p11)], and three mosaics [mos45,X/46,X,idic(Y)(q11)]. In general, these findings are in accordance with those from other surveys and confirm that the XXY aneuploidy is the most frequent chromosomal abnormality in azoospermic individuals.


Asunto(s)
Trastornos de los Cromosomas/epidemiología , Oligospermia/genética , Aberraciones Cromosómicas , Humanos , Síndrome de Klinefelter/epidemiología , Masculino , México/epidemiología , Estudios Retrospectivos
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