RESUMEN
The design of molecular catalysts that mimic the behavior of enzymes is a topical field of activity in emerging technologies, and can lead to an improved understanding of biological systems. Herein, we report how the bulky arms of the cations in [(n C4 H9 )4 N](+) [HCO3 ](-) give rise to a host scaffold that emulates the substrate binding sites in carbonic anhydrase enzymes, affording a unique glimpse of an arrested intermediate in the base-mediated binding and activation of CO2 .
Asunto(s)
Bicarbonatos/química , Materiales Biomiméticos/química , Dióxido de Carbono/metabolismo , Anhidrasas Carbónicas/química , Compuestos de Amonio Cuaternario/química , Bicarbonatos/metabolismo , Sitios de Unión , Materiales Biomiméticos/metabolismo , Biomimética , Anhidrasas Carbónicas/metabolismo , Cristalografía por Rayos X , Modelos Moleculares , Compuestos de Amonio Cuaternario/metabolismoRESUMEN
Preliminary results are reported for the extraction and catalytic hydrocracking of Alberta bitumen and oil sands using supercritical fluid mixtures; high levels of extraction and upgrading were attained using reaction conditions significantly milder than those previously reported.