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1.
Musculoskelet Surg ; 97(3): 223-8, 2013 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-23852661

RESUMEN

BACKGROUND: Management of early stages of osteonecrosis aims to prevent the collapse of the femoral head by attempts at restoring the vascularity of femoral head. Bone marrow-derived mononuclear cells with their angiogenic and osteogenic properties appear to have the potential to halt the disease process when injected intralesionally following core decompression. MATERIALS AND METHODS: Forty patients (60 hips) with stage I, II or III (ARCO system) osteonecrosis of femoral head were treated by either core decompression and isolated mononuclear cells (group A) or core decompression and unprocessed bone marrow injection (group B). The patients were followed up clinically and radiologically for a minimum of 2 years. The functional outcome was assessed in terms of Harris hip score, and disease progression was assessed radiologically by comparing the preoperative and follow-up MRI at the end of 2 years. RESULTS: On 2-year follow-up, there was considerable improvement in the hip function as measured by the Harris hip score in both the groups (p = 0.031). On MRI, there was a decrease in the size of the lesion in group A (p = 0.03). Three of 30 hips (10.0 %) in group B required total hip replacement. CONCLUSIONS: Implantation of autologous bone marrow stem cells in avascular necrosis of femoral head is a safe and effective procedure and has better outcome than bone marrow for early stage of avascular necrosis of femoral head.


Asunto(s)
Necrosis de la Cabeza Femoral/terapia , Trasplante de Células Madre Mesenquimatosas , Adulto , Trasplante de Médula Ósea , Separación Celular , Descompresión Quirúrgica , Progresión de la Enfermedad , Femenino , Estudios de Seguimiento , Humanos , Inyecciones Intralesiones , Masculino , Células Madre Mesenquimatosas , Neovascularización Fisiológica , Osteogénesis , Recuperación de la Función , Índice de Severidad de la Enfermedad , Trasplante Autólogo , Resultado del Tratamiento
2.
Nepal Med Coll J ; 14(2): 163-4, 2012 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-23671971

RESUMEN

Elbow dislocation with ipsilateral diaphyseal fracture of both radius and ulna is a rare injury. However, elbow dislocation with either radius or ulnar diaphyseal fracture is commonly reported. We report an uncommon injury of a 16 years old male who had his elbow dislocation with ipsilateral both bones forearm fractures. Elbow dislocation was reduced and fracture both bones were fixed with dynamic compression plate under brachial block.


Asunto(s)
Lesiones de Codo , Fracturas del Radio/complicaciones , Fracturas del Cúbito/complicaciones , Adolescente , Articulación del Codo/diagnóstico por imagen , Fijación Interna de Fracturas , Humanos , Masculino , Radiografía , Fracturas del Radio/diagnóstico por imagen , Fracturas del Radio/cirugía , Fracturas del Cúbito/diagnóstico por imagen , Fracturas del Cúbito/cirugía
3.
Nepal Med Coll J ; 12(3): 193-7, 2010 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-21446372

RESUMEN

We share the literature and management of an adult with moderate hemophilia a presented with a calcaneal pseudotumor and non healing ulcer by radiation therapy, factor VIII and cryoprecipitate supplement. Numerous literatures so far have quoted the satisfactory role of radiotherapy in hemophilic pseudotumor. We found it to be of great help as our case responded with radiotherapy, factor VIII and cryoprecipitate supplement and has a satisfactory 2 years follow up.


Asunto(s)
Hematoma/radioterapia , Hemofilia A/complicaciones , Artropatías/radioterapia , Úlcera Cutánea/radioterapia , Adulto , Articulación del Tobillo , Hematoma/etiología , Humanos , Artropatías/etiología , Masculino , Úlcera Cutánea/etiología , Adulto Joven
4.
Nepal Med Coll J ; 11(3): 207-8, 2009 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-20334074

RESUMEN

Long bone injuries are less common during caesarian section. Sometimes, they remain unnoticed to the operating surgeon but are frequently noted by attending physician or nurses. The aim of this case study is to remind the surgeon that any forceful extraction may result long bone injuries. So, care should be given during and after delivery to rule out injuries.


Asunto(s)
Traumatismos del Nacimiento/epidemiología , Cesárea/efectos adversos , Fracturas del Fémur/etiología , Fracturas del Húmero/etiología , Fracturas del Fémur/epidemiología , Humanos , Fracturas del Húmero/epidemiología , Recién Nacido , Masculino , Nepal/epidemiología
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