RESUMEN

Whole cells of the propene utilizing Mycobacterium sp. M156 (NCIMB 40156) oxidised styrene, 2-,3- and 4-fluorostyrene, 3- and 4-chlorostyrene and 3- and 4-methylstyrenes to their respective epoxides. Rates of oxidation were comparable to that of styrene. alpha-Methylstyrene was also epoxidised at a lower rate, while trans-beta-methylstyrene and 1,2-dihydronaphthalene were poor substrates. In those cases that were investigated, epoxidation occurred with a high degree of stereospecificity.

Asunto(s)

Compuestos Epoxi/síntesis química , Mycobacterium/metabolismo , Estirenos/síntesis química , Biotransformación , Cromatografía de Gases , Compuestos Epoxi/química , Compuestos Epoxi/metabolismo , Cromatografía de Gases y Espectrometría de Masas , Cinética , Rotación Óptica , Estereoisomerismo , Estireno , Estirenos/química , Estirenos/metabolismo , Especificidad por Sustrato