RESUMEN

Epidermolysis bullosa acquisita (EBA) is a subepidermal autoimmune blistering disease that is rarely reported in childhood. We describe a nine-month-old mulatto boy presenting with multiple, annular, widespread, tense blisters and oral lesions. The diagnosis of EBA was confirmed by histopathology, immunofluorescence, and immunoblotting analysis. The patient was successfully treated with systemic steroids (prednisone) and dapsone. After 20 months of initial treatment, clinical remission was observed, and dapsone remains as the current treatment. This case report emphasizes the rarity of EBA in childhood and the difficulties in reaching the final diagnosis.

Asunto(s)

Dapsona/administración & dosificación , Epidermólisis Ampollosa Adquirida/diagnóstico , Epidermólisis Ampollosa Adquirida/tratamiento farmacológico , Prednisona/administración & dosificación , Administración Oral , Biopsia con Aguja , Quimioterapia Combinada , Técnica del Anticuerpo Fluorescente Indirecta , Estudios de Seguimiento , Humanos , Lactante , Masculino , Medición de Riesgo , Índice de Severidad de la Enfermedad , Resultado del Tratamiento