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1.
Comput Methods Programs Biomed ; 111(1): 93-103, 2013 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-23669177

RESUMEN

The tear film lipid layer is heterogeneous among the population. Its classification depends on its thickness and can be done using the interference pattern categories proposed by Guillon. This papers presents an exhaustive study about the characterisation of the interference phenomena as a texture pattern, using different feature extraction methods in different colour spaces. These methods are first analysed individually and then combined to achieve the best results possible. The principal component analysis (PCA) technique has also been tested to reduce the dimensionality of the feature vectors. The proposed methodologies have been tested on a dataset composed of 105 images from healthy subjects, with a classification rate of over 95% in some cases.


Asunto(s)
Lípidos/química , Lípidos/clasificación , Lágrimas/química , Adulto , Color , Bases de Datos Factuales , Humanos , Cadenas de Markov , Microscopía de Interferencia/estadística & datos numéricos , Fenómenos Ópticos , Análisis de Componente Principal , Máquina de Vectores de Soporte , Análisis de Ondículas , Adulto Joven
2.
Comput Math Methods Med ; 2012: 207315, 2012.
Artículo en Inglés | MEDLINE | ID: mdl-22567040

RESUMEN

The tear film lipid layer is heterogeneous among the population. Its classification depends on its thickness and can be done using the interference pattern categories proposed by Guillon. The interference phenomena can be characterised as a colour texture pattern, which can be automatically classified into one of these categories. From a photography of the eye, a region of interest is detected and its low-level features are extracted, generating a feature vector that describes it, to be finally classified in one of the target categories. This paper presents an exhaustive study about the problem at hand using different texture analysis methods in three colour spaces and different machine learning algorithms. All these methods and classifiers have been tested on a dataset composed of 105 images from healthy subjects and the results have been statistically analysed. As a result, the manual process done by experts can be automated with the benefits of being faster and unaffected by subjective factors, with maximum accuracy over 95%.


Asunto(s)
Lípidos/química , Lípidos/clasificación , Lágrimas/química , Adulto , Algoritmos , Inteligencia Artificial , Color , Bases de Datos Factuales , Humanos , Interferometría/estadística & datos numéricos , Cadenas de Markov , Modelos Estadísticos , Adulto Joven
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