RESUMEN
The authors present the incidence of new cases of tuberculosis of the lungs treated at the Clinic of Tuberculosis and Lung Diseases in the years 1994-1998. This study evaluates the clinical forms of tuberculosis, rate of debacillisation, age stratification and the incidence of diseases associated with severe tuberculosis.
Asunto(s)
Tuberculosis Pulmonar , Femenino , Humanos , Incidencia , Masculino , Persona de Mediana Edad , Eslovaquia/epidemiología , Tuberculosis Pulmonar/diagnóstico , Tuberculosis Pulmonar/tratamiento farmacológico , Tuberculosis Pulmonar/etiologíaRESUMEN
The laboratory measurements of the reversibility of airways obstruction is assessed by performing pulmonary function tests before and after administration of bronchodilators. Controversial issues relating to bronchodilator testing include: selection of bronchodilator, dosage, pattern of inhalation of the drug, timing of the postbronchodilator test, physiologic tests utilized, criteria for the significant response, and the role of glucocorticoids in the relief of airways obstruction.
Asunto(s)
Pruebas de Provocación Bronquial , Enfermedad Pulmonar Obstructiva Crónica/diagnóstico , Algoritmos , Broncodilatadores/uso terapéutico , Diagnóstico Diferencial , Humanos , Enfermedad Pulmonar Obstructiva Crónica/tratamiento farmacológicoRESUMEN
The authors studied the rate of relief in cases of moderate, reversible airway obstruction after Furosemide administration. They examined 25 patients with bronchial asthma and chronic obstructive bronchitis (mean age 49 years). They found out that intravenous administration of Furosemide to patients with chronic obstructive bronchitis has a significant bronchodilating effect. The reduction of interstitial lung water and the decrease in congestion of airways mucosa in latent left ventricular failure may be the possible explanations of this phenomenon. After administration of Furosemide by inhalation, a mild decrease in airway obstruction was observed in asthmatic patients. The influence of Na+/K+/Cl- transport in the bronchial epithelium, or changes in PGE2 are supposed to represent the effective mechanisms. The authors conclude that Furosemide given intravenously to patients with moderate airflow limitation in connection with lung function tests may be helpful in the diagnosis of the nature of airway obstruction.
Asunto(s)
Asma/diagnóstico , Bronquios/efectos de los fármacos , Bronquitis/diagnóstico , Furosemida , Administración por Inhalación , Asma/fisiopatología , Bronquios/fisiopatología , Bronquitis/fisiopatología , Enfermedad Crónica , Femenino , Furosemida/administración & dosificación , Humanos , Inyecciones Intravenosas , Masculino , Persona de Mediana EdadRESUMEN
The case of a 17 year old patient with severe course of toxocariasis is reported. Over a period of 6 months the patient developed signs of serious systemic condition with fever, respiratory infections, diarrhea, urticaria, weight loss, and muscular atrophies. The most remarkable organ derangements involved bilateral exudative neuroretinitis, severe degree of peripheral motoneuron derangement, and grave kidney damage with developing polyuria, hypokalemia, metabolic alkalosis and therapeutically hardly tractable hypertension. The most important laboratory findings were high erythrocyte sedimentation, absolute and relative eosinophilia, and hypergammaglobulinemia. Serological examination exhibited weak larval toxocariasis positivity. Treatment with Mintezol and subsequent administration of prednisone resulted in complete restoration of the clinical state, including organ and laboratory manifestations. The reported case documents the occurrence of larval toxocariasis in our population as well as the possibility of a very severe course of this parasitic infection in man. The therapeutic effect is remarkable since literary data have so far reported mostly unsatisfactory results of toxocariasis treatment.