RESUMEN

A model of multiple lung metastases in BDIX rats is under study at CNEA (Argentina) to evaluate the feasibility of BNCT for multiple, non-surgically resectable lung metastases. A practical shielding device that comfortably houses a rat, allowing delivery of a therapeutic, uniform dose in lungs while protecting the body from the neutron beam is presented. Based on the final design obtained by numerical simulations, the shield was constructed, experimentally characterized and recently used in the first in vivo experiment at RA-3.

Asunto(s)

Terapia por Captura de Neutrón de Boro/instrumentación , Neoplasias Pulmonares/radioterapia , Neoplasias Pulmonares/secundario , Protección Radiológica/instrumentación , Planificación de la Radioterapia Asistida por Computador/métodos , Animales , Diseño Asistido por Computadora , Diseño de Equipo , Análisis de Falla de Equipo , Dosificación Radioterapéutica , Ratas