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1.
Eur J Vasc Endovasc Surg ; 48(3): 285-91, 2014 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-24962744

RESUMEN

OBJECTIVES: Uncomplicated acute type B aortic dissection (AD) treated conservatively has a 10% 30-day mortality and up to 25% need intervention within 4 years. In complicated AD, stent grafts have been encouraging. The aim of the present prospective randomised trial was to compare best medical treatment (BMT) with BMT and Gore TAG stent graft in patients with uncomplicated AD. The primary endpoint was a combination of incomplete/no false lumen thrombosis, aortic dilatation, or aortic rupture at 1 year. METHODS: The AD history had to be less than 14 days, and exclusion criteria were rupture, impending rupture, malperfusion. Of the 61 patients randomised, 80% were DeBakey type IIIB. RESULTS: Thirty-one patients were randomised to the BMT group and 30 to the BMT+TAG group. Mean age was 63 years for both groups. The left subclavian artery was completely covered in 47% and in part in 17% of the cases. During the first 30 days, no deaths occurred in either group, but there were three crossovers from the BMT to the BMT+TAG group, all due to progression of disease within 1 week. There were two withdrawals from the BMT+TAG group. At the 1-year follow up there had been another two failures in the BMT group: one malperfusion and one aneurysm formation (p = .056 for all). One death occurred in the BMT+TAG group. For the overall endpoint BMT+TAG was significantly different from BMT only (p < .001). Incomplete false lumen thrombosis, was found in 13 (43%) of the TAG+BMT group and 30 (97%) of the BMT group (p < .001). The false lumen reduced in size in the BMT+TAG group (p < .001) whereas in the BMT group it increased. The true lumen increased in the BMT+TAG (p < .001) whereas in the BMT group it remained unchanged. The overall transverse diameter was the same at the beginning and after 1 year in the BMT group (42.1 mm), but in the BMT+TAG it decreased (38.8 mm; p = .062). CONCLUSIONS: Uncomplicated AD can be safely treated with the Gore TAG device. Remodelling with thrombosis of the false lumen and reduction of its diameter is induced by the stent graft, but long term results are needed.


Asunto(s)
Disección Aórtica/cirugía , Implantación de Prótesis Vascular/métodos , Procedimientos Endovasculares/métodos , Enfermedad Aguda , Europa (Continente) , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estudios Prospectivos , Stents , Resultado del Tratamiento
2.
J Cardiovasc Surg (Torino) ; 53(2): 161-8, 2012 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-22456637

RESUMEN

AIM: In-hospital outcome of acute type B dissection (ABAD) is strongly related to preoperative aortic conditions. In order to clarify the influence of the clinical presentation on the outcome, we analyzed the patients of the International Registry of Acute Aortic Dissection (IRAD). All patients affected by complicated ABAD, enrolled in the IRAD from 1996-2004, were included. Complications were defined as the presence of shock, periaortic hematoma, spinal cord ischemia, preoperative mesenteric ischemia/infarction, acute renal failure, limb ischemia, recurrent pain, refractory pain or refractory hypertension (group I). All other patients were categorized as uncomplicated (group II). A comprehensive analysis was performed of all clinical variables in relation to in-hospital outcome. RESULTS: The overall in-hospital mortality among 550 patients was 12.4%. Mortality in group I (250 patients) was 20.0 %, compared to 6.1% in group II (300 patients) (P<0.001). Univariate predictors of ABAD complications were Marfan syndrome, abrupt onset of pain, migrating pain, any focal neurological deficits, need for higher number of diagnostic examinations and use of magnetic resonance and/or aortogram, abdominal vessels involvement at aortogram, larger descending aortic diameter, especially >6 cm, pleural effusion, and widened mediastinum on chest X-ray. Univariate predictors of a non complicated status were normal chest X-ray and medical management. In group I, in-hospital mortality following surgical and endovascular intervention were 28.6% and 10.1% (P=0.006), respectively. Independent predictors of overall in-hospital mortality included age >70 years, female gender, ECG showing ischemia, preoperative acute renal failure, preoperative limb ischemia, periaortic hematoma, and surgical management. The only independent variable protective for mortality was magnetic resonance as diagnostic test. CONCLUSION: ABAD is a heterogeneous disease that produces dissimilar clinical subsets, each of which can have specific clinical signs, management and in-hospital results. In IRAD ABAD uncomplicated patients, medical therapy was associated with best hospital outcome, while endovascular interventions were associated with better results than surgery when invasive treatments were required. Although selection bias may be possible, and irrespective of treatments, knowledge of significant risk factors for mortality may contribute to a better management and a more defined risk-assessment in patients affected by ABAD.


Asunto(s)
Aneurisma de la Aorta Torácica/cirugía , Disección Aórtica/cirugía , Evaluación de Resultado en la Atención de Salud , Sistema de Registros , Procedimientos Quirúrgicos Vasculares , Enfermedad Aguda , Anciano , Disección Aórtica/diagnóstico , Disección Aórtica/mortalidad , Aneurisma de la Aorta Torácica/diagnóstico , Aneurisma de la Aorta Torácica/mortalidad , Aortografía , Femenino , Estudios de Seguimiento , Mortalidad Hospitalaria/tendencias , Humanos , Imagen por Resonancia Magnética , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Estados Unidos/epidemiología
3.
Int Angiol ; 31(1): 22-7, 2012 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-22330621

RESUMEN

AIM: The aim of this preliminary study is to evaluate the feasibility and efficacy of CAS as treatment option to endarterectomy when carotid shunt cannot be used safely. METHODS: The medical records concerning 469 carotid stenosis treated between January 2006 and December 2009 were retrospectively reviewed, focusing on cross-clamp intolerance during CEA. Patients with cross-clamping intolerance were divided in two groups. Group 1: those that concluded the open procedure with the use of a shunt, and Group 2: those who experience immediate brain intolerance and coma and were immediately converted to an endovascular procedure. Mortality and neurological adverse event rate were compared between shunted CEA and cross-clamping intolerant cases converted into CAS. The secondary end-point was long-term survival. RESULTS: Carotid cross-clamp intolerance occurred in 30 cases (8.7%). CEA with Pruitt-Inahara's shunt was performed in 17 cases with a perioperative neurological adverse event rate of 23.5%. In 13 cases limitations to shunting due to quick onset of coma and/or an unfavorable anatomy were encountered. In these 13 cases the open intervention was immediately converted into endovascular procedure. Technical success was achieved in all the converted to CAS cases (100%), with a perioperative neurological adverse event rate of 7.7% (P=0.35 between the two groups). No significant difference emerges comparing patient's survival between the cases CONCLUSION: Nevertheless, the small dimension of this survey, immediate conversion to CAS resulted feasible with a lower risk of neurological adverse events if compared to CEA with shunt, and could be considered as an alternative to CEA when carotid shunt cannot be used safely.


Asunto(s)
Angioplastia/instrumentación , Estenosis Carotídea/terapia , Trastornos Cerebrovasculares/prevención & control , Endarterectomía Carotidea/efectos adversos , Stents , Anciano , Anciano de 80 o más Años , Angioplastia/efectos adversos , Angioplastia/mortalidad , Estenosis Carotídea/diagnóstico , Estenosis Carotídea/mortalidad , Estenosis Carotídea/fisiopatología , Estenosis Carotídea/cirugía , Angiografía Cerebral , Circulación Cerebrovascular , Trastornos Cerebrovasculares/diagnóstico , Trastornos Cerebrovasculares/etiología , Trastornos Cerebrovasculares/fisiopatología , Constricción , Endarterectomía Carotidea/mortalidad , Estudios de Factibilidad , Femenino , Humanos , Italia , Estimación de Kaplan-Meier , Angiografía por Resonancia Magnética , Masculino , Persona de Mediana Edad , Modelos de Riesgos Proporcionales , Sistema de Registros , Estudios Retrospectivos , Factores de Tiempo , Resultado del Tratamiento , Ultrasonografía Doppler en Color
4.
J Cardiovasc Surg (Torino) ; 52(4): 529-38, 2011 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-21792160

RESUMEN

Morbidity and mortality after conventional open repair of post-dissecting thoracoabdominal aortic aneurysms (TAAA) remain high despite the improvement of results. Recently, "hybrid" open de-branching procedures combined with endovascular stent-grafting of the atherosclerotic thoracic aortic aneurisms have been performed, as an alternative approach. However, patients with significant cardiac, pulmonary or renal comorbidities, may represent an unfit cohort also for such hybrid procedures, and, of consequence, may be resigned to medical treatment. Recent experiences with fenestrated and branched stent-grafts have opened new opportunities in the treatment of extensive aortic aneurysms involving the visceral and renal arteries, particularly in case of atherosclerotic aneurysms. Post-dissection thoracoabdominal aneurysms present with additional challenges such as narrow true lumen at the level of the visceral vessels origin, and the lack of a stable distal landing zone. In this report, we discuss the role of fenestrated and branched stent-grafts as feasible treatment of post-dissecting TAAA.


Asunto(s)
Aneurisma de la Aorta Torácica/cirugía , Disección Aórtica/cirugía , Implantación de Prótesis Vascular/instrumentación , Prótesis Vascular , Procedimientos Endovasculares/instrumentación , Stents , Disección Aórtica/mortalidad , Aneurisma de la Aorta Torácica/mortalidad , Implantación de Prótesis Vascular/efectos adversos , Implantación de Prótesis Vascular/mortalidad , Enfermedad Crónica , Procedimientos Endovasculares/efectos adversos , Procedimientos Endovasculares/mortalidad , Humanos , Selección de Paciente , Diseño de Prótesis , Medición de Riesgo , Resultado del Tratamiento
5.
Minerva Chir ; 64(1): 101-3, 2009 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-19202538

RESUMEN

This paper presents the description of the author's experience with bifurcated endovascular stent graft in a patient affected by spontaneous infrarenal acute aortic dissection (SIAAD). The authors report a case of SIAAD occurring in the normal aorta of a patient who presented with severe lower back pain radiated to the abdomen, not responding to common pain-killers. A complete exclusion of the dissected aorta was accomplished with a bifurcated endovascular graft using a simple technique. SIAAD is a rare event. Endovascular therapy is a safe option and can be considered the treatment of choice even for dissection extending into one or both iliac.


Asunto(s)
Aneurisma de la Aorta/cirugía , Disección Aórtica/cirugía , Implantación de Prótesis Vascular/métodos , Stents , Enfermedad Aguda , Disección Aórtica/diagnóstico , Aorta Abdominal/cirugía , Aneurisma de la Aorta/diagnóstico , Humanos , Masculino , Persona de Mediana Edad , Diseño de Prótesis , Arteria Renal , Factores de Tiempo , Resultado del Tratamiento , Procedimientos Quirúrgicos Vasculares/métodos
6.
Eur J Vasc Endovasc Surg ; 33(2): 214-6, 2007 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-17127082

RESUMEN

INTRODUCTION: We report a two centre experience with a depopulated ureteric xenograft (SGVG 100), CryoLife Inc., GA, USA) for femoropopliteal revascularization in 12 patients with chronic critical limb ischemia. REPORT: Between 7 days and 18 months after implantation, 10 of 12 patients (1 lost to follow-up) had the graft explanted due to aneurysmal enlargement. At 5 years, only one graft was still patent and showed moderate signs of enlargement. CONCLUSION: The SGVG 100 is not a safe conduit for femoropopliteal bypass surgery.


Asunto(s)
Arteriopatías Oclusivas/cirugía , Implantación de Prótesis Vascular/instrumentación , Arteria Femoral/cirugía , Isquemia/cirugía , Pierna/irrigación sanguínea , Arteria Poplítea/cirugía , Uréter/trasplante , Angiografía , Animales , Arteriopatías Oclusivas/complicaciones , Arteriopatías Oclusivas/diagnóstico , Bovinos , Arteria Femoral/diagnóstico por imagen , Estudios de Seguimiento , Humanos , Isquemia/diagnóstico , Isquemia/etiología , Arteria Poplítea/diagnóstico por imagen , Diseño de Prótesis , Estudios Retrospectivos , Factores de Tiempo , Trasplante Heterólogo , Resultado del Tratamiento , Ultrasonografía Doppler en Color
8.
J Cardiovasc Surg (Torino) ; 43(5): 701-3, 2002 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-12386588

RESUMEN

Acute type A aortic dissection and coarctation of the aorta is a rare associated disease. A case of two-stage repair is presented. Firstly the ascending aorta and the right hemi-arch was replaced using deep hypo-thermic circulatory arrest. Cardiopulmonary bypass was proximally instituted, in a patient with total aortic isthmus occlusion, using right axillary artery cannulation. Distally arterial perfusion was obtained cannulating the bilateral hypoplasic femoral arteries. Ten months later a left subclavian artery-descending thoracic aorta bypass was performed.


Asunto(s)
Aneurisma de la Aorta/cirugía , Coartación Aórtica/cirugía , Disección Aórtica/cirugía , Procedimientos Quirúrgicos Cardíacos , Disección Aórtica/complicaciones , Aneurisma de la Aorta/complicaciones , Coartación Aórtica/complicaciones , Implantación de Prótesis Vascular , Femenino , Paro Cardíaco Inducido , Humanos , Hipotermia Inducida , Persona de Mediana Edad
9.
J Cardiovasc Surg (Torino) ; 42(5): 691-4, 2001 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-11562603

RESUMEN

A 50-year-old man with Behçet's disease (BD) diagnosed ten years previously, was submitted to emergency operation of two symptomatic type IV thoracoabdominal aortic and left common iliac aneurysms repair. Despite the rarity of vascular lesions in the course of BD, the uncommon clinical situation of double symptomatic aneurysms was successfully treated with surgical management that appears more difficult because of the inflammatory process associated with obliterative endoarteritis involving all periaortic tissues.


Asunto(s)
Aneurisma/cirugía , Aneurisma de la Aorta/cirugía , Síndrome de Behçet/complicaciones , Arteria Ilíaca , Aneurisma/diagnóstico , Aneurisma/etiología , Angiografía , Aneurisma de la Aorta/diagnóstico , Aneurisma de la Aorta/etiología , Humanos , Masculino , Persona de Mediana Edad , Tomografía Computarizada por Rayos X
10.
Circulation ; 104(12 Suppl 1): I288-95, 2001 Sep 18.
Artículo en Inglés | MEDLINE | ID: mdl-11568071

RESUMEN

BACKGROUND: Structural alterations of aortic wall resulting from degradation of matrix proteins by matrix metalloproteinases (MMPs) characterize abdominal aortic aneurysms (AAAs). No studies have compared circulating levels of MMPs after endovascular graft (EVG) exclusion in comparison with open surgical repair (OSR) in patients affected by AAA. METHODS AND RESULTS: An abdominal angiography and CT scan were performed in all patients at the time of enrollment. A spiral CT scan was performed at 6 months to detect presence of endoleaks. MMP-3 and MMP-9 levels were measured before EVG (n=30) and OSR (n=15) treatments and at 1, 3, and 6 months of follow-up by a sandwich ELISA technique. Healthy volunteers (n=10) were used as control subjects. Immunohistochemical staining for MMP-9 and MMP-3 was performed on tissue samples from surgical cases. Both MMP-9 and MMP-3 mean basal levels were significantly higher in patients affected by AAA than in control subjects (32.3+/-20.7 ng/mL for EVG and 28+/-9.9 ng/mL for OSR versus 8.9+/-2.5 ng/mL, 2P<0.05; 18.3+/-9.7 ng/mL and 26.7+/-10.8 ng/mL versus 8.2+/-5.3 ng/mL, 2P<0.001). In the OSR group, both MMP-9 and MMP-3 mean levels decreased after surgery (28+/-9.9 ng/mL at basal versus 14.7+/-6.6 ng/mL at 6 months, 2P<0.001; 26.7+/-10.8 versus 12+/-5.3 ng/mL; 2P<0.001). In the EVG group, a statistically significant difference at 6-month follow-up in MMP-9 and MMP-3 mean plasma values was detected in patients who had endoleakage in comparison with patients without endoleakage (44.3+/-20.7 versus 14.6+/-7.0 ng/mL, 2P<0.005; 25+/-11.5 versus 10.3+/-5.4 ng/mL, 2P<0.005). CONCLUSIONS: After EVG exclusion, MMP-9 and MMP-3 levels decreased to a level similar to that of patients undergoing OSR. In addition, a lack of decrease in MMP levels after EVG exclusion may help in identifying patients who will have endoleakage and consequent aneurysm expansion caused by continuous sac pressurization during follow-up.


Asunto(s)
Aneurisma de la Aorta Abdominal/sangre , Metaloproteinasa 3 de la Matriz/sangre , Procedimientos Quirúrgicos Vasculares , Anciano , Aneurisma de la Aorta Abdominal/patología , Aneurisma de la Aorta Abdominal/cirugía , Aortografía , Biomarcadores/sangre , Implantación de Prótesis Vascular/efectos adversos , Cateterismo , Femenino , Estudios de Seguimiento , Humanos , Inmunohistoquímica , Masculino , Persona de Mediana Edad , Valor Predictivo de las Pruebas , Falla de Prótesis , Valores de Referencia , Stents/efectos adversos , Inhibidor Tisular de Metaloproteinasa-1/sangre , Inhibidor Tisular de Metaloproteinasa-2/sangre , Tomografía Computarizada por Rayos X , Procedimientos Quirúrgicos Vasculares/efectos adversos
11.
Eur J Cardiothorac Surg ; 19(4): 531-3, 2001 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-11306330

RESUMEN

Proximal pseudoaneurysm of ascending-abdominal aortic bypass is an uncommon surgical disease. We report a repair of complete detachment of proximal anastomosis of the ascending-abdominal aortic bypass in a 68-year-old man that underwent surgery in 1988 for chronic descending thoracic aortic aneurysm treated with thromboesclusion technique. The clinical, diagnostic, and operative aspects are discussed.


Asunto(s)
Aneurisma Falso/cirugía , Aneurisma de la Aorta Abdominal/cirugía , Anciano , Aneurisma Falso/diagnóstico por imagen , Aneurisma de la Aorta Abdominal/diagnóstico por imagen , Humanos , Masculino , Radiografía
12.
Minerva Chir ; 53(5): 397-403, 1998 May.
Artículo en Italiano | MEDLINE | ID: mdl-9780631

RESUMEN

MATERIALS AND METHODS: In the period 1986-1994, 2950 patients with cardiovascular diseases were surgically treated. In 2104 cases we placed biological or synthetic grafts to maintain vascular continuity. The most common has turned out to be abdominal aortic aneurysm. We treated 783 cases in emergency conditions. Staging and localization of infection has been the first aim in patients with synthetic vascular grafts. We studied signs and symptoms related to infections. In all cases we discovered the microorganism responsible of infection we started antibiotic therapy. RESULTS: Surgical infection incidence is 4.9% (154 cases). Series analysis has evidenced a decrease in infection incidence in the period 1986-1994. The most frequent infections are: the urinary tract infection (59 cases, 38.5%) followed by surgical wound infection (37 cases, 24.1%), respiratory tract infection (27 cases, 17.5%), vascular graft infection (23 cases, 14.4%). All patients underwent a preoperative antibiotic prophylaxis with 2 degrees-3 degrees generation cephalosporines. We noted a higher graft infection incidence in patients treated with aortobifemoral reconstruction. We handled surgical infection following two main directions: 1-antibiotic therapy, 2-surgical treatment and antibiotic therapy. CONCLUSIONS: We noted surgical technique improvement and correct application of an antibiotic prophylaxis form has turned out to be the "gold standard" in order to reduce cardiovascular surgical infections. To reduce sepsis or graft infection we can work on either of the following: 1) antibiotic therapy; 2) operative time reduction; 3) try to limit vascular surgery in case of concomitant gastrointestinal surgical disease; 4) using alloplastic vascular grafts with high biological compliance; 5) patency time reduction of invasive diagnostic technique.


Asunto(s)
Profilaxis Antibiótica , Infecciones Bacterianas/prevención & control , Complicaciones Posoperatorias/prevención & control , Enfermedades Vasculares/cirugía , Aneurisma de la Aorta Abdominal/cirugía , Arteriopatías Oclusivas/cirugía , Humanos , Infecciones Relacionadas con Prótesis/prevención & control , Estudios Retrospectivos , Infección de la Herida Quirúrgica/prevención & control , Tromboembolia/cirugía
13.
Minerva Cardioangiol ; 44(1-2): 29-32, 1996.
Artículo en Italiano | MEDLINE | ID: mdl-8767619

RESUMEN

Peripheral arterial aneurysms present characteristic locations. In the lower limbs, atherosclerotic aneurysms of the deep femoral artery are very rare. Authors report an interesting case of arteriosclerotic aneurysm of a branch of the profunda femoris artery observed in a 80 year-old man, and associated with an abdominal aortic aneurysm. Endo-aneurysmectomy was performed with a dacron patch interposition. Surgical treatment of this rate disease is discussed.


Asunto(s)
Aneurisma , Arteriosclerosis , Arteria Femoral , Anciano , Anciano de 80 o más Años , Aneurisma/diagnóstico , Aneurisma/cirugía , Aneurisma de la Aorta Abdominal/complicaciones , Aneurisma de la Aorta Abdominal/diagnóstico , Aneurisma de la Aorta Abdominal/cirugía , Prótesis Vascular , Arteria Femoral/cirugía , Humanos , Masculino , Tereftalatos Polietilenos
14.
Panminerva Med ; 37(3): 123-8, 1995 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-8869366

RESUMEN

Fifteen cases of ruptured thoracoabdominal aneurysm (-TAA) were encountered in 1987-July 1994. These patients included 13 males (86.6%), 2 females (13.4%) with a mean age of 66.3 years (range 58-78). Surgery was performed on 13 patients of whom 6 (46.1%) died within 30 days. The two other patients had died of heart failure prior to surgery. In 8 of these patients (53.4%) the condition was not diagnosed until clear symptoms had appeared. The ruptured aneurysms were thoracic in 9 cases (60%), abdominal in 6 (40%). The maximum aneurysm diameter in the most frequently ruptured group was 6.1-8 cm (in 9 patients-60%)./ For 5 cases (33.4%) the maximum diameter of ruptured aneurysms included dorsolumbar pain. In one patient a concomitant aortobronchial fistula had produced rupture. Low blood pressure was found in 9 cases (60%). In 5 cases (38.4%) curative surgery was performed within 24 hours of the onset of symptoms. In this group, the mortality rate was 40% (2 patients). In the remaining 8 cases, on whom surgery could not be performed within 24 hours (range 25 hours-4 months) the mortality rate was 50% (4 cases). All four cases of paraplegia (30.7%) were encountered among patients in the second group, 2 of whom died. Follow-up revealed a 5-year mortality rate of 71.4%.


Asunto(s)
Aneurisma Roto , Aorta Abdominal , Aorta Torácica , Anciano , Aneurisma Roto/mortalidad , Aneurisma Roto/cirugía , Femenino , Humanos , Masculino , Persona de Mediana Edad , Mortalidad , Enfermedades del Sistema Nervioso/etiología , Complicaciones Posoperatorias , Análisis de Supervivencia , Factores de Tiempo
15.
Minerva Cardioangiol ; 42(7-8): 351-7, 1994.
Artículo en Italiano | MEDLINE | ID: mdl-7970029

RESUMEN

Inflammatory abdominal aneurysms (AIAA) represent a clearly defined clinical entity with an incidence ranging between 1.2% and 15%. In spite of the increasing number of observations reported in recent years, the etiopatholgenesis and natural history have not been defined. The lesion can present in an acute, subacute or chronic manner and the histopathological studies reveal prevalently two components: an inflammatory infiltrate and a diffuse fibrosis, in varying degree. This study aimed to analyze the more recent imaging procedures in order to correctly diagnose this lesion. In our experience the incidence of AIAA is about 2.5%. On the basis of macro microscopic pictures the authors divided patients into two groups: one constituted by the acute or subacute inflammatory forms, the other by chronic clear inflammatory aneurysms. All patients underwent on operative treatment. The surgical adopted techniques and the obtained results are reported.


Asunto(s)
Aneurisma de la Aorta Abdominal , Anciano , Anciano de 80 o más Años , Aorta Abdominal/patología , Aneurisma de la Aorta Abdominal/diagnóstico , Aneurisma de la Aorta Abdominal/patología , Aneurisma de la Aorta Abdominal/cirugía , Diagnóstico Diferencial , Femenino , Humanos , Inflamación , Imagen por Resonancia Magnética , Masculino , Persona de Mediana Edad , Cintigrafía , Tomografía Computarizada por Rayos X
16.
Minerva Cardioangiol ; 41(11): 501-10, 1993 Nov.
Artículo en Italiano | MEDLINE | ID: mdl-8127451

RESUMEN

There is an altered hemostatic balance in vascular-based diseases. The aim of this study was to compare a group (no. = 38) of vascular patients (aortic aneurysm, carotid obstructions arteriopathies of lower limbs) and a control group (no. = 40) and assess variations in the following endothelial factors: tPA, PAI1, vWf, fibronectin and dimer D, in differentiated degrees according to the type of pathology. These were the indicative signs of endothelial mobilization resulting in the renewed continuity of the stratum with the formation of a hemostatic plug. vWf was found to be particularly significant as a marker of an ongoing atheromasic process and its extension to various vascular districts.


Asunto(s)
Aneurisma de la Aorta/sangre , Estenosis Carotídea/sangre , Enfermedades Vasculares/sangre , Adulto , Anciano , Aneurisma de la Aorta/fisiopatología , Arteriosclerosis/fisiopatología , Estenosis Carotídea/fisiopatología , Factores de Crecimiento Endotelial/metabolismo , Femenino , Fibronectinas/metabolismo , Hemostasis , Humanos , Pierna/irrigación sanguínea , Masculino , Persona de Mediana Edad , Activadores Plasminogénicos/metabolismo , Activador de Tejido Plasminógeno/metabolismo , Enfermedades Vasculares/fisiopatología , Factor de von Willebrand/metabolismo
17.
Minerva Cardioangiol ; 41(7-8): 325-9, 1993.
Artículo en Italiano | MEDLINE | ID: mdl-8233015

RESUMEN

Chronic renal insufficiency is one of the most important factors governing the immediate and long-term outcome after aneurysm repair. A total of 484 patients with abdominal aortic aneurysm (A.A.A.) have undergone elective surgical treatment in our Institution during the last 5 years. Of these, we selected 60 patients; 30 with a normal serum creatinine concentration and 30 with preoperative renal insufficiency (serum creatinine concentration greater than 2 mg/dl). In this second group, 23 patients (76.6%) were affected by slight or median renal insufficiency, 5 patients (16.6%) were affected by severe renal insufficiency (creatinine concentration greater than 4.5 mg/dl), and 2 patients (6.6%) had complete renal failure with dialytic treatment from 1.5 and 2 years respectively. We analyzed postoperative renal function in all 60 patients. In the first group, only 6 patients (20%) showed a transient renal insufficiency, without mortality and morbidity. In the second group, postoperative complications and mortality tended to occur more frequently in patients with a severe renal insufficiency than in patients with slight or median insufficiency or complete renal failure. The present data suggest that dialytic treatment might be necessary in patients with severe renal insufficiency before aneurysm repair.


Asunto(s)
Aneurisma de la Aorta Abdominal/cirugía , Fallo Renal Crónico/complicaciones , Aneurisma de la Aorta Abdominal/complicaciones , Femenino , Humanos , Masculino , Pronóstico
18.
J Cardiovasc Surg (Torino) ; 34(3): 221-8, 1993 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-8344972

RESUMEN

From 1970 to October 1991, 26 patients affected by splanchnic artery aneurysms were observed and treated at the Department of General and Cardiovascular Surgery, University of Milan, Italy. Three splanchnic artery aneurysms were operated on in emergency. Visceral artery aneurysms are often completely silent and are generally detected during diagnostic procedures performed in order to clarify some diagnostic questions. When symptomatic they present a characteristic clinical picture of the involved vascular district. Two patients affected by aneurysmal disease of the proper hepatic artery died after operation. All the other splanchnic aneurysms underwent a successful surgical procedure. This study is aimed at analyzing some characteristic clinical pictures, diagnostic methods, therapeutic procedures and postoperative results.


Asunto(s)
Aneurisma/cirugía , Circulación Esplácnica , Adulto , Anciano , Aneurisma/diagnóstico por imagen , Aneurisma Roto/diagnóstico por imagen , Aneurisma Roto/cirugía , Angiografía , Urgencias Médicas , Femenino , Humanos , Masculino , Persona de Mediana Edad , Rotura Espontánea , Tomografía Computarizada por Rayos X
19.
Minerva Chir ; 47(9): 823-9, 1992 May 15.
Artículo en Italiano | MEDLINE | ID: mdl-1620476

RESUMEN

The femoral region is the most common site of development of anastomotic pseudoaneurysms that represent a relatively frequent complication of reconstructive vascular surgery. Clinical examination alone generally is sufficient to diagnose these lesions because they usually appear as a pulsatile inguinal mass not accompanied by pain. Echography and angiodynography permit a better evaluation of size and blood flow. CT is useful to evaluate proximal aortic anastomosis specially in pseudoaneurysms with septic pathogenesis. Rupture or thrombosis are rare clinical presentations. Vascular reconstructive surgery is always suggested in this sort of pathology. In this paper the Authors report the clinical experience acquired from 1980 to 1990 in the General and Cardiovascular Surgery Department of the University of Milan (Head: Prof. Ugo Ruberti) is 34 cases of femoral anastomotic aseptic pseudoaneurysms, analyzing the pathogenesis of this sort of lesion, describing the surgical solutions adopted and reporting the immediate and late results.


Asunto(s)
Anastomosis Quirúrgica/efectos adversos , Aneurisma/cirugía , Arteria Femoral/cirugía , Anciano , Anciano de 80 o más Años , Aneurisma/etiología , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad
20.
Minerva Chir ; 46(19): 1005-14, 1991 Oct 15.
Artículo en Italiano | MEDLINE | ID: mdl-1771020

RESUMEN

A series of 100 patients suffering from deep venous thrombosis with prior episodes of pulmonary embolism or ilio-caval floating thrombi, submitted to surgery for the prevention of new embolic episodes, is analysed. Indications are discussed together with the various prevention techniques adopted over the past 5 years. Special attention is paid to the analysis of 11 patients operated on in the last 2 years by thrombectomy of the infra- and suprarenal vena cava.


Asunto(s)
Complicaciones Posoperatorias/prevención & control , Embolia Pulmonar/prevención & control , Tromboflebitis/cirugía , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Femenino , Humanos , Masculino , Persona de Mediana Edad , Complicaciones Posoperatorias/etiología , Embolia Pulmonar/etiología , Tromboflebitis/complicaciones , Filtros de Vena Cava , Vena Cava Inferior/cirugía , Vena Cava Superior/cirugía
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