Asunto(s)

Melaninas/biosíntesis , Melanosomas/metabolismo , Animales , Citosol/metabolismo , Humanos , Concentración de Iones de Hidrógeno , Cinética , Melanocitos/metabolismo , Monofenol Monooxigenasa/metabolismo , Pigmentación

RESUMEN

Vitiligo among the community Somavashan Sahasajuna Kashatriya(SSK) of Baugalore surveyed by us during February-March, 1987, was found to be characterised by an earlier age of onset and a very high (90.38%) familial incidence. This community at present is small and is believed to have migrated'from Gujarat-Maharashtra border where the incidence of vitiligo in a related community, the Khatris is already high (3.6%). The results indicate that continuous inbreeding among the SSK community in Bangalore may have enhanced their genetic predisposition to this disease.