RESUMEN

We present the case of a 55 yr female who had recurrent severe hypoglycemic attacks with neuroglycopenic symptoms and altered sensorium including coma. The hypoglycemic episodes were not related to fasting. The hypoglycemia was hyperinsulinemic but all imaging modalities for insulinoma were negative. Selective arterial calcium stimulation test localized the lesion to splenic artery territory and distal pancreatectomy left to the splenic vein was done. The histopathology was consistent with nesidioblastosis and gradient guided pancreatectomy relieved the hypoglycemic episodes.

Asunto(s)

Calcio , Hiperinsulinismo/diagnóstico , Hipoglucemia/diagnóstico , Insulina/sangre , Glucemia/metabolismo , Péptido C/sangre , Calcio/sangre , Femenino , Humanos , Hiperinsulinismo/complicaciones , Hiperinsulinismo/cirugía , Hipoglucemia/etiología , Hipoglucemia/cirugía , Hipoglucemiantes/uso terapéutico , Inmunohistoquímica , Inyecciones Intraarteriales , Insulinoma/sangre , Insulinoma/patología , Persona de Mediana Edad , Pancreatectomía , Neoplasias Pancreáticas/sangre , Neoplasias Pancreáticas/patología , Esplenectomía , Síndrome , Resultado del Tratamiento