1.
Chem Commun (Camb)
; 60(14): 1928-1931, 2024 Feb 13.
Artículo
en Inglés
| MEDLINE
| ID: mdl-38268331
RESUMEN
Developing new chemotherapeutics that are structurally and mechanistically unique is needed due to the rapid rise of the cancer incidence across the globe. Here, we report the identification of irreversible, thiol-reactive diazepam derivatives as GPX4 modifiers and nanomolar inducers of ferroptosis in liver cancer cells.