RESUMEN
In a typical experiment on decision making, one out of two possible stimuli is displayed and observers decide which one was presented. Recently, Stanford and colleagues (2010) introduced a new variant of this classical one-stimulus presentation paradigm to investigate the speed of decision making. They found evidence for "perceptual decision making in less than 30 ms". Here, we extended this one-stimulus compelled-response paradigm to a two-stimulus compelled-response paradigm in which a vernier was followed immediately by a second vernier with opposite offset direction. The two verniers and their offsets fuse. Only one vernier is perceived. When observers are asked to indicate the offset direction of the fused vernier, the offset of the second vernier dominates perception. Even for long vernier durations, the second vernier dominates decisions indicating that decision making can take substantial time. In accordance with previous studies, we suggest that our results are best explained with a two-stage model of decision making where a leaky evidence integration stage precedes a race-to-threshold process.
Asunto(s)
Toma de Decisiones/fisiología , Adulto , Femenino , Humanos , Percepción/fisiología , Estimulación Física , Factores de TiempoRESUMEN
Decisions about noisy stimuli require evidence integration over time. Traditionally, evidence integration and decision making are described as a one-stage process: a decision is made when evidence for the presence of a stimulus crosses a threshold. Here, we show that one-stage models cannot explain psychophysical experiments on feature fusion, where two visual stimuli are presented in rapid succession. Paradoxically, the second stimulus biases decisions more strongly than the first one, contrary to predictions of one-stage models and intuition. We present a two-stage model where sensory information is integrated and buffered before it is fed into a drift diffusion process. The model is tested in a series of psychophysical experiments and explains both accuracy and reaction time distributions.
Asunto(s)
Toma de Decisiones , Adulto , Algoritmos , Biología Computacional/métodos , Difusión , Discriminación en Psicología , Femenino , Humanos , Masculino , Variaciones Dependientes del Observador , Tiempo de Reacción , Reproducibilidad de los Resultados , Programas Informáticos , Factores de TiempoRESUMEN
Most models of vision focus either on the spatial or temporal aspects of visual processing and neglect the other component. A variety of studies have shown, however, that spatial and temporal processing cannot easily be separated. The shine-through effect has proven to be a sensitive tool to study spatio-temporal processing. Two very different dynamical models, the 3D-LAMINART and the WCTM model, have explained the key aspects of the shine-through effect. Based on computer simulations Francis (2009) proposed a set of predictions based on stimulus variants of the shine-through effect that are crucial for both models. Here, we tested these predictions psychophysically. Both models fail to correctly predict the outcome of these experiments.
Asunto(s)
Modelos Biológicos , Percepción Visual/fisiología , Adulto , Discriminación en Psicología , Femenino , Humanos , Masculino , Reconocimiento Visual de Modelos/fisiología , Umbral Sensorial , Percepción Espacial/fisiología , Adulto JovenRESUMEN
How the brain integrates visual information across time into coherent percepts is an open question. Here, we presented two verniers with opposite offset directions one after the other. A vernier consists of two vertical bars that are horizontally offset. When the two verniers are separated by a blank screen (interstimulus interval, ISI), the two verniers are perceived either as two separate entities or as one vernier with the offset moving from one side to the other depending on the ISI. In both cases, their offsets can be reported independently. Transcranial magnet stimulation (TMS) over the occipital cortex does not interfere with the offset discrimination of either vernier. When a grating, instead of the ISI, is presented, the two verniers are not perceived separately anymore, but as 'one' vernier with 'one' fused vernier offset. TMS strongly modulates the percept of the fused vernier offset even though the spatio-temporal position of the verniers is identical in the ISI and grating conditions. We suggest that the grating suppresses the termination signal of the first vernier and the onset signal of the second vernier. As a consequence, perception of the individual verniers is suppressed. Neural representations of the vernier and second vernier inhibit each other, which renders them vulnerable to TMS for at least 300 ms, even though stimulus presentation was only 100 ms. Our data suggest that stimulus features can be flexibly integrated in the occipital cortex, mediated by neural interactions with outlast stimulus presentations by far.
Asunto(s)
Lóbulo Occipital/fisiología , Estimulación Magnética Transcraneal/métodos , Percepción Visual/fisiología , Adulto , Femenino , Humanos , Masculino , Estimulación Luminosa/métodos , Adulto JovenRESUMEN
In the present study we tested the applicability of a paired-stimulus paradigm for the investigation of near-threshold (NT) stimulus processing in the somatosensory system using magnetoencephalography. Cortical processing of the NT stimuli was studied indirectly by investigating the impact of NT stimuli on the source activity of succeeding suprathreshold test stimuli. We hypothesized that cortical responses evoked by test stimuli are reduced due to the preactivation of the same finger representation by the preceding NT stimulus. We observed attenuation of the magnetic responses in the secondary somatosensory (SII) cortex, with stronger decreases for perceived than for missed NT stimuli. Our data suggest that processing in the primary somatosensory cortex including recovery lasts for <200 ms. Conversely, the occupancy of SII lasts >/=500 ms, which points to its role in temporal integration and conscious perception of sensory input.
Asunto(s)
Corteza Cerebral/fisiología , Umbral Sensorial/fisiología , Tacto/fisiología , Adolescente , Adulto , Mapeo Encefálico , Interpretación Estadística de Datos , Electroencefalografía , Potenciales Evocados Somatosensoriales/fisiología , Femenino , Humanos , Magnetoencefalografía , Masculino , Estimulación Física , Desempeño Psicomotor/fisiología , Adulto JovenRESUMEN
The human brain analyzes a visual object first by basic feature detectors. On the objects way to a conscious percept, these features are integrated in subsequent stages of the visual hierarchy. The time course of this feature integration is largely unknown. To shed light on the temporal dynamics of feature integration, we applied transcranial magnetic stimulation (TMS) to a feature fusion paradigm. In feature fusion, two stimuli which differ in one feature are presented in rapid succession such that they are not perceived individually but as one single stimulus only. The fused percept is an integration of the features of both stimuli. Here, we show that TMS can modulate this integration for a surprisingly long period of time, even though the individual stimuli themselves are not consciously perceived. Hence, our results reveal a long-lasting integration process of unconscious feature traces.
Asunto(s)
Lóbulo Occipital/fisiología , Estimulación Magnética Transcraneal , Percepción Visual/fisiología , Adulto , Estado de Conciencia , Discriminación en Psicología , Femenino , Humanos , Masculino , Estimulación Luminosa/métodos , Tiempo de Reacción , Umbral Sensorial , Adulto JovenRESUMEN
The influential model on visual information processing by Milner and Goodale (1995) has suggested a dissociation between action- and perception-related processing in a dorsal versus ventral stream projection. It was inspired substantially by the observation of a double dissociation of disturbed visual action versus perception in patients with optic ataxia on the one hand and patients with visual form agnosia (VFA) on the other. Unfortunately, almost all cases with VFA reported so far suffered from inhalational intoxication, the majority with carbon monoxide (CO). Since CO induces a diffuse and widespread pattern of neuronal and white matter damage throughout the whole brain, precise conclusions from these patients with VFA on the selective role of ventral stream structures for shape and orientation perception were difficult. Here, we report patient J.S., who demonstrated VFA after a well circumscribed brain lesion due to stroke etiology. Like the famous patient D.F. with VFA after CO intoxication studied by Milner, Goodale, and coworkers (Goodale et al., 1991, 1994; Milner et al., 1991; Servos et al., 1995; Mon-Williams et al., 2001a,b; Wann et al., 2001; Westwood et al., 2002; McIntosh et al., 2004; Schenk and Milner, 2006), J.S. showed an obvious dissociation between disturbed visual perception of shape and orientation information on the one side and preserved visuomotor abilities based on the same information on the other. In both hemispheres, damage primarily affected the fusiform and the lingual gyri as well as the adjacent posterior cingulate gyrus. We conclude that these medial structures of the ventral occipitotemporal cortex are integral for the normal flow of shape and of contour information into the ventral stream system allowing to recognize objects.
Asunto(s)
Agnosia/etiología , Lóbulo Occipital/fisiopatología , Reconocimiento Visual de Modelos/fisiología , Accidente Cerebrovascular/complicaciones , Accidente Cerebrovascular/patología , Lóbulo Temporal/fisiopatología , Anciano , Anciano de 80 o más Años , Agnosia/patología , Discriminación en Psicología/fisiología , Femenino , Fuerza de la Mano/fisiología , Humanos , Imagen por Resonancia Magnética/métodos , Masculino , Pruebas Neuropsicológicas , Orientación/fisiología , Estimulación Luminosa , Percepción del Tamaño/fisiología , Factores de TiempoRESUMEN
The rat whisker system has evolved into in an excellent model system for sensory processing from the periphery to cortical stages. However, to elucidate how sensory processing finally relates to percepts, methods to assess psychophysical performance pertaining to precise stimulus kinematics are needed. Here, we present a head-fixed, behaving rat preparation that allowed us to measure detectability of a single whisker deflection as a function of amplitude and peak velocity. We found that velocity thresholds for detection of small-amplitude stimuli (<3 degrees) were considerably higher than for detection of large-amplitude stimuli (>3 degrees). This finding suggests the existence of two psychophysical channels mediating detection of whisker deflection: one channel exhibiting high amplitude and low velocity thresholds (W1), and the other channel exhibiting high velocity and low amplitude thresholds (W2). The correspondence of W1 to slowly adapting (SA) and W2 to rapidly adapting (RA) neuronal classes in the trigeminal ganglion was revealed in acute neurophysiological experiments. Neurometric plots of SA and RA cells were closely aligned to psychophysical performance in the corresponding W1 and W2 parameter ranges. Interestingly, neurometric data of SA cells fit the behavior best if it was based on a short time window integrating action potentials during the initial phasic response, in contrast to integrating across the tonic portion of the response. This suggests that detection performance in both channels is based on the assessment of very few spikes in their corresponding groups of primary afferents.