RESUMEN
BACKGROUND: Intraoperative pulmonary embolism (PE) with cardiac arrest (CA) represents a critical and potentially fatal condition. Available treatments include systemic thrombolysis, catheter-based thrombus fragmentation or aspiration, and surgical embolectomy. However, limited studies are focused on the optimal treatment choice for this critical condition. We present a case series and an updated review of the management of intraoperative CA secondary to PE. METHODS: A retrospective review of patients who developed high-risk intraoperative PE was performed between June 2012 and June 2022. For the updated review, a literature search on PubMed and Scopus was conducted which resulted in the inclusion of a total of 46 articles. RESULTS: A total of 196 174 major non-cardiac surgeries were performed between 2012 and 2022. Eight cases of intraoperative CA secondary to high-risk PE were identified. We found a mortality rate of 75%. Anticoagulation therapy was administered to one patient (12.5%), while two patients (25%) underwent thrombolysis, and one case (12.5%) underwent mechanical thrombectomy combined with thrombus aspiration. Based on the literature review and our 10-year experience, we propose an algorithm for the management of intraoperative CA caused by PE. CONCLUSION: The essential components for adequate management of intraoperative PE with CA include hemodynamic support, cardiopulmonary resuscitation, and the implementation of a primary perfusion intervention. The prompt identification of the criteria for each specific treatment modality, guided by the individual patient's characteristics, is necessary for an optimal approach.
Asunto(s)
Paro Cardíaco , Embolia Pulmonar , Trombosis , Humanos , Terapia Trombolítica/efectos adversos , Terapia Trombolítica/métodos , Resultado del Tratamiento , Embolia Pulmonar/complicaciones , Embolia Pulmonar/cirugía , Trombosis/complicaciones , Trombosis/cirugía , Paro Cardíaco/terapia , Paro Cardíaco/complicacionesRESUMEN
En niños con insuficiencia o estenosis valvular significativa, la intervención de la válvula, ya sea valvuloplastia o reemplazo valvular, suele ser inevitable. El seguimiento de estos pacientes puede ser complejo; los síntomas iniciales de disfunción valvular protésica son inespecíficos y en ocasiones es difícil diferenciar entre los efectos de la disfunción valvular, las patologías no cardíacas, la disfunción ventricular y la hipertensión pulmonar. Aunque el examen físico puede alertar al clínico acerca de alteraciones, se requieren otros métodos diagnósticos para evaluar la función de la prótesis. La ecocardiografía Doppler es el método de elección no invasivo para estudiar la función valvular y pese a que muchas de las mediciones y parámetros de normalidad y anormalidad son extrapolados de estudios en adultos, se han tratado de definir estándares en pacientes pediátricos. Este documento ofrece una revisión acerca de las técnicas usadas en el estudio de las válvulas protésicas con base en literatura científica, consensos internacionales y opiniones de expertos.
In children with significant valvular insufficiency or stenosis, valve surgery, either valvuloplasty or valve replacement is usually inevitable. The monitoring of these patients can be complex, the initial symptoms of prosthetic valve dysfunction are nonspecific and sometimes difficult to differentiate between the effects of valvular dysfunction, non-cardiac pathologies, ventricular dysfunction and pulmonary hypertension. Although physical examination may alert the clinician about alterations, other diagnostic methods to assess the function of the prosthesis is required. Doppler echocardiography is the noninvasive method of choice to study valvular function and although many of the measurements and parameters of normality and abnormality are extrapolated from adult studies have been attempted to define standards in pediatric patients. This document provides an overview about the techniques used in the study of prosthetic valves based on scientific literature, international consensus and expert opinion.