Asunto(s)

Pared Abdominal , Tercer Trimestre del Embarazo , Ultrasonografía Prenatal , Femenino , Humanos , Embarazo , Pared Abdominal/anomalías , Pared Abdominal/diagnóstico por imagen , Pared Abdominal/embriología

RESUMEN

We have isolated a chicken cDNA that encodes the retinoblastoma susceptibility gene product (RB). The predicted amino acid sequence of the chicken RB protein is highly similar to that of the mouse, human and Xenopus RB proteins in regions of known functions; however, chicken RB has distinct species-specific differences, including a shorter N-terminal region as compared to the mouse and human RB proteins. In vitro-translated chicken RB co-migrates on SDS-polyacrylamide gels with endogenous RB synthesized in transformed chicken spleen cells. Finally, chicken RB is located in the nucleus of chicken embryo fibroblasts when overexpressed from a retroviral vector.

Asunto(s)

Proteína de Retinoblastoma/genética , Secuencia de Aminoácidos , Animales , Secuencia de Bases , Embrión de Pollo , Pollos , ADN , ADN Complementario , Humanos , Datos de Secuencia Molecular , Homología de Secuencia de Aminoácido