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To overcome obstacles hindering the commercialization of lithium-ion batteries (LIBs) and sodium-ion batteries (SIBs), we introduce a cost-effective single-step sulfurization strategy for synthesizing iron sulfide (Fe0.975S) nanohybrids, augmented by N,S codoped carbon. The resulting N,S codoped carbon-coated Fe0.975S (Fe0.975S@NSC) electrode exhibits exceptional potential as a highly reversible anode material for both LIBs and SIBs. With impressive initial discharge and charge capacities (1658.2 and 1254.9 mAh g-1 for LIBs and 1450.9 and 1077.1 mAh g-1 for SIBs), the electrode maintains substantial capacity retention (900 mA h g-1 after 1000 cycles for LIBs and 492.5 mA h g-1 after 600 cycles for SIBs at 1.0 A g-1). The LiMn2O4//Fe0.975S@NSC and Na3V2(PO4)3//Fe0.975S@NSC full batteries can maintain excellent reversible capacity and robust cycling stability. Ex situ and in situ X-ray diffraction, density functional theory (DFT) calculations, and kinetics analysis confirm the promising energy storage potential of the Fe0.975S@NSC composite.

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FeS, with its high theoretical capacity and natural abundance, holds significant promise as an anode material for lithium-ion batteries (LIBs). However, its practical application is constrained by poor electrical conductivity and substantial volume expansion during cycling, which impair charge-discharge efficiency and cycling stability. To overcome these challenges, we developed a nitrogen and sulfur co-doped carbon-encapsulated FeS composite with a hollow double-layer structure (HDL-FeS@NSC). Utilizing sulfur spheres as a sacrificial template, our inside-out synthesis strategy produces a unique material design. The HDL-FeS@NSC composite exhibits significant improvements in electrochemical performance compared to pure FeS. These enhancements are due to its increased specific surface area, which facilitates lithium-ion diffusion; a shortened Li+ diffusion pathway; structural stability that mitigates volume expansion; and an optimized carbon layer that boosts conductivity. The HDL-FeS@NSC-70 anode demonstrates a specific capacity of 879.6 mAh/g after 600 cycles at 1.0 A/g and retains 558.0 mAh/g at 5.0 A/g. Additionally, the lithium storage mechanism has been thoroughly investigated using in-situ techniques. These results suggest that the HDL-FeS@NSC composite anode has the potential to significantly enhance lithium-ion battery performance, offering a promising solution for next-generation energy storage systems.

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A drug-drug cocrystal created with two antithrombotic-active ingredients from herbs, honokiol (HON) and ligustrazine (TMP, 1:1), was synthesized and characterized. The structure of HON-TMP (1:1) was determined by single-crystal X-ray diffraction. Then co-amorphous HON-TMP was prepared by honey-assisted grinding, which was inspired by a grinding process for a Chinese patent medicine-Shijunzi honey pill. This co-amorphous drug-drug cocrystal (20% honey) exhibits improved solubility over HON and a significantly reduced sublimation tendency than TMP.

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The practical application of Molybdenum sulphide (MoS2) electrodes has been hindered by its structural instability, and poor electrical conductivity. To enhance the cycle stability and rate performance of MoS2in lithium/sodium-ion batteries (LIBs/SIBs), we synthesized a graphene-supported MoS2composite (MoS2@rGO) with affluent covalent bridged bonds through a facile and scalable hydrothermal and annealing process. The covalent bridged bonds of Mo-S-C, Mo-O-C and C-O-S provide an effective charge transfer path between MoS2and graphene, facilitating fast charge hopping and improving rate performance. As anode materials for LIBs, the MoS2@rGO exhibited exceptional long-term cycle life (906 mAh g-1at 1.0 A g-1after 400 cycles) and outstanding rate capability (1267.7/314.7 mAh g-1at 0.1/6.5 A g-1). Additionally, the MoS2@rGO electrode demonstrated a stable reversible capacity of 521.7 mAh g-1at 1.0 A g-1after 700 cycles and excellent rate capabilities of 665.1 and 326.3 mAh g-1at 0.1 and 10.0 A g-1in SIBs. The edge Mo of MoS2is directly coupled with the oxygen of the functional group on rGO, achieved by adjusting the pH value of the solution to tune the surface charge feature, can effectively enhance the structural stability of electrode even under higher current density.

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Atherosclerosis, a chronic disease of arteries, results in high mortality worldwide as the leading cause of cardiovascular disease. The development of clinically relevant atherosclerosis involves the dysfunction of endothelial cells and vascular smooth muscle cells. A large amount of evidence indicates that noncoding RNAs, such as microRNAs (miRNAs), long noncoding RNAs (lncRNAs), and circular RNAs (circRNAs), are involved in various physiological and pathological processes. Recently, noncoding RNAs were identified as key regulators in the development of atherosclerosis, including the dysfunction of endothelial cells, and vascular smooth muscle cells and it is pertinent to understand the potential function of noncoding RNAs in atherosclerosis development. In this review, the latest available research relates to the regulatory role of noncoding RNAs in the progression of atherosclerosis and the therapeutic potential for atherosclerosis is summarized. This review aims to provide a comprehensive overview of the regulatory and interventional roles of ncRNAs in atherosclerosis and to inspire new insights for the prevention and treatment of this disease.

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Under the new normal of economic growth, implementing environmental regulation policies and developing digital finance have become essential factors affecting high-quality economic development. This study aims to examine whether environmental regulation has a positive effect on high-quality economic development and what impact digital finance has in the process of environmental regulation affecting high-quality economic development. This study uses the panel data of 30 provinces in China from 2011 to 2019 to measure the high-quality economic development by using the entropy-TOPSIS method based on constructing an indicator system for high-quality economic development. Then, environmental regulations are classified into four categories: economic, command based, legal, and supervised, and digital finance is included in the analysis framework. The impact of heterogeneous environmental regulations on high-quality economic development and the indirect influence mechanism played by digital finance are empirically analyzed. The results show that command-based environmental regulation significantly hinders improving economic development quality. In contrast, supervised environmental regulation plays a significant positive role and can therefore serve as an essential driver of high-quality economic development. In addition, digital finance plays a significant positive moderating role in the influence of environmental regulation on the economy's high-quality development level. After the robustness test, the conclusion is still valid. Further heterogeneity analysis shows that the impact of environmental regulation on high-quality economic development and the moderating effect of digital finance differ across dimensions of economic quality development and have regional heterogeneity. The research findings are conducive to formulating appropriate environmental regulation policies and giving full play to the positive role of digital finance, providing support for promoting high-quality economic development.

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BACKGROUND: Mitochondria play critical roles in cellular physiological activity as cellular organelles. Under extracellular stimulation, mitochondria undergo constant fusion and fission to meet different cellular demands. Mitochondrial dynamics, which are involved in mitochondrial fusion and fission, are regulated by specialized proteins and lipids, and their dysregulation causes human diseases, such as cancer. The advanced literature about the crucial role of mitochondrial dynamics in breast cancer is performed. METHODS: All related studies were systematically searched through online databases (PubMed, Web of Science, and EMBASE) using keywords (e.g., breast cancer, mitochondrial, fission, and fusion), and these studies were then screened through the preset inclusion and exclusion criteria. RESULTS: Eligible studies (n = 19) were evaluated and discussed in the systematic review. These advanced studies established the roles of mitochondrial fission and fusion of breast cancer in the metabolism, proliferation, survival, and metastasis. Importantly, the manipulating of mitochondrial dynamic is significant for the progresses of breast cancer. CONCLUSION: Understanding the mechanisms underlying mitochondrial fission and fusion during tumorigenesis is important for improving breast cancer treatments.

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