RESUMEN
Locally advanced gastric adenocarcinoma has a poor outcome. Neoadjuvant treatment is being tested in locally advanced non-resectable tumours and in those resectable tumours with a high risk of recurrence. Efforts to identify prognostic factors and more active and less toxic preoperative regimens are being searched for. We report the case of a patient achieving a complete histopathological complete response following docetaxel- based neoadjuvant chemotherapy.
Asunto(s)
Adenocarcinoma/tratamiento farmacológico , Antineoplásicos/uso terapéutico , Neoplasias Gástricas/tratamiento farmacológico , Taxoides/uso terapéutico , Adulto , Quimioterapia Adyuvante , Progresión de la Enfermedad , Docetaxel , Humanos , Masculino , Terapia NeoadyuvanteAsunto(s)
Autoinmunidad , Quimioterapia Adyuvante , Interferón-alfa/efectos adversos , Melanoma/tratamiento farmacológico , Autoanticuerpos/sangre , Enfermedades Autoinmunes/inducido químicamente , Ensayos Clínicos Fase III como Asunto/estadística & datos numéricos , Relación Dosis-Respuesta a Droga , Estudios de Seguimiento , Humanos , Sistema Inmunológico/efectos de los fármacos , Interferón-alfa/administración & dosificación , Interferón-alfa/farmacología , Interferón-alfa/uso terapéutico , Melanoma/inmunología , Melanoma/mortalidad , Pronóstico , Púrpura Trombocitopénica Idiopática/inducido químicamente , Ensayos Clínicos Controlados Aleatorios como Asunto , Análisis de Supervivencia , Tirotoxicosis/inducido químicamente , Vitíligo/inducido químicamenteRESUMEN
Cardiac metastases are more frequent than primary heart neoplasias. Nearly any malignant tumour may metastasize to the heart, but the most common are carcinomas rather than sarcomas. We report the case of a patient who presented with heart metastasis 6 years after resection of an uterine leiomyosarcoma. The patient died thirty months after surgical resection without evidence of cardiac recurrence. Although cardiac metastases from uterine leiomyosarcoma are exceptional, they should be suspected in the presence of suggestive symptoms, since they can be associated with long survival after surgical treatment.