RESUMEN

Lycium Barbarum Polysaccharides (LBP) can benefit lipid parameters such as total cholesterol, triglyceride, and high-density lipoprotein levels and upregulate the level of Firmicutes, increase the diversity of gut microbiota and reduce metabolic disorders, finally relieving weight gain of obese rats. But it cannot reverse the outcome of obesity. Over 30 differential metabolites and four pathways are altered by LBP.

Asunto(s)

Dieta Alta en Grasa , Medicamentos Herbarios Chinos , Microbioma Gastrointestinal , Obesidad , Animales , Microbioma Gastrointestinal/efectos de los fármacos , Obesidad/tratamiento farmacológico , Ratas , Medicamentos Herbarios Chinos/farmacología , Medicamentos Herbarios Chinos/química , Masculino , Lycium/química , Estructura Molecular , Triglicéridos/sangre , Triglicéridos/metabolismo , Ratas Sprague-Dawley , Polisacáridos/farmacología , Polisacáridos/química