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ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION: Is there variation in the depth of the curve of Spee in individuals with different dentoskeletal patterns? A systematic review with meta-analysis. Paes-Souza Sde, Marañón-Vásquez GA, Galisteu-Luiz K et al. Europ J Orthodont. 2022;44(5):491-502. SOURCE OF FUNDING: This study was supported in part by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Brasil (CAPES), Finance code DS 001, and Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ - APQ1, number E-26/210.435/2019). TYPE OF STUDY/DESIGN: Systematic review.

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Pooled estimates indicate about 226 million individuals are currently experiencing or have experienced persistent symptoms from COVID-19. Long COVID-19 (LC) has been associated with a prolonged inflammatory and stress responses in affected individuals. Due to common pathways, LC could impact the biological mechanisms of orthodontic tooth movement, orthodontically-induced inflammatory root resorption and periodontal tissue response of patients undergoing orthodontic treatment. The authors of the present report discussed potential biological mechanisms through which LC may influence orthodontic treatment highlighting the need for further research in this area.