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1.
J Oral Biol Craniofac Res ; 13(1): 28-35, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-36345495

RESUMEN

Objective: This systematic review and meta-analysis aimed to evaluate if bioceramic sealers had superior sealing properties to epoxy resin-based sealers. Methodology: A systematic search was performed in the following databases: MEDLINE Ovid (from 1946 onwards), Scopus, Google Scholar, EBSCO, and a hand search of references of included articles was also done. In vitro and ex vivo studies were included. Risk of bias was assessed, and quantitative synthesis was performed for microleakage measured using vertical dye penetration, horizontal dye penetration, and dentin-sealer gap. Summary effect was reported as Standardized Mean Difference with 95% CI. Subgroup analysis was performed based on the imaging modalities, the obturation techniques, and the file systems employed. Results: A total of 24 studies were included. Meta-analysis demonstrated no significant difference between the sealing ability of bioceramic sealer and epoxy resin-based sealer when measured using the microleakage tests [SMD -0.59(95%CI: 1.74,0.55)]. Subgroup analysis revealed no significant differences except when manual K-files were used. Heterogeneity was low when sub-group analysis was done. Conclusion: Bioceramic sealers and epoxy resin-based sealers both exhibited comparable sealing ability.

2.
J Pharm Bioallied Sci ; 13(Suppl 1): S132-S136, 2021 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-34447061

RESUMEN

BACKGROUND: Microleakage is a concern while restoring cervical lesions. Many products have attempted to minimize the interfacial gap between the tooth and restoration, the main pathway of microleakage. AIMS AND OBJECTIVE: To compare and evaluate the microleakage in Class V cavity restored with nanohybrid flowable composite, Resin modified Glass Ionomer and Cention N. METHOD: Class V cavities were prepared on mandibular premolars on buccal surface with their occlusal margin placed in enamel and the gingival margin in dentin. The teeth were randomly assigned to three groups of 20 teeth each and restored with Flowable composite , Resin Modified GIC and Cention N. Samples were immersed in 0.5% Rhodamine dye, sectioned and microleakage measured using Confocal Laser Scanning Microscopy. Statistical analysis was done using Oneway ANOVA Bonferroni's test and Kruskal Waliis test. RESULTS: The average depth of penetration of dye and scoring of depth were noted. On comparing dye penetration values between groups, RMGIC is compared with Flowable composite and Cention N, statistically significant result was obtained suggesting lesser dye penetration in RMGIC group (P < 0.001) where other comparison did not. CONCLUSION: RMGIC showed significantly less microleakage compared to the other two restorative materials used in the study and enamel margin of all restorations showed lesser microleakage than dentin margin.

3.
J Pharm Bioallied Sci ; 12(Suppl 1): S546-S549, 2020 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-33149518

RESUMEN

BACKGROUND: Dental caries is considered to be one of the most prevalent dental diseases among humans. It involves cycles of demineralization and remineralization. The etiology and pathogenesis of dental caries are multifactorial. The role of diet plays an important aspect in occurrence and progression of dental caries. Indians have differing dietary habits due to various religious and personal reasons. A substantial number of Indians are vegetarian by choice. AIM: The aim of this study was to assess the effect of vegetarian and mixed diet over the prevalence of dental caries. MATERIALS AND METHODS: This observational cross-sectional study was conducted among 104 individuals. Healthy subjects who were 20-40 years of age, with no systemic disease, and not on any medications were included in this study. A thorough dental examination was performed by a single investigator with the help of mouth mirror and probe. The examination of patients involved the sequential assessment of teeth starting from 1 to 32. All the exposed and accessible surfaces of the teeth were examined for dental caries, and the data were recorded. STATISTICAL ANALYSIS: The data obtained were statistically analyzed using the Statistical Package for the Social Sciences (SPSS) software, version 11.0, and the results were tabulated. Univariate analysis was performed to find an association between caries and diet. RESULTS: Distribution of the respondents according to dietary practices revealed 51% of the population consuming mixed diet and 49% consuming vegetarian diet. Oral hygiene was measured in terms of frequency of brushing tooth. Among the enrolled subjects, 57% brushed their teeth once a day and 42% brushed twice a day. No significant association was found between vegetarian and mixed dietary habits and dental caries. Two-sample independent t test was carried out to find the mean age. The mean age of caries group was 30.93 ± 12.27 and in without caries group, 27.83 ± 11.58, which is statistically not significant (P = 0.218). CONCLUSION: The study did not show any significant association between dietary habits and prevalence of dental caries.

4.
J Indian Soc Periodontol ; 18(6): 723-7, 2014.
Artículo en Inglés | MEDLINE | ID: mdl-25624628

RESUMEN

AIM: Periodontitis is a multifactorial disease, with microbial dental plaque as the primary etiological factor. However, the manifestation and progression of periodontitis is influenced by a wide variety of other determinants and factors such as social and behavioral factors, systemic factors, microbial composition of dental plaque, genetic, and many other emerging risk factors. The aim of this study was to analyze genetic polymorphisms in the toll-like receptor 9 (TLR9) gene at - 1237C/T and its association with chronic and generalized aggressive periodontitis (GAgP) in an Indian population. MATERIALS AND METHODS: This study was carried out on 90 subjects, which included 30 GAgP and 30 chronic periodontitis patients and 30 healthy controls. Within the limitations of our study, only 30 subjects were included in each group due to the low prevalence of GAgP patients. Blood samples were drawn from the subjects and analyzed for TLR9 genetic polymorphism at - 1237C/T by using polymerase chain reaction-restriction fragment length polymorphism method. RESULTS: No significant difference was found in genotype and allele frequency of TLR9 genetic polymorphism (- 1237C/T) in generalized aggressive and chronic periodontitis patients and healthy controls. CONCLUSION: Toll-like receptor 9 genetic polymorphism at - 1237C/T may not be associated with GAgP and chronic periodontitis patients in Indian population.

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