RESUMEN
In many cicumstances, veterinarians are requiring to be able to administer rabies vaccine in dogs at the same time as vaccinating against canine distemper, adenovirus, parvovirus, parainfluenza virus and leptospirosis. The aim of this study was to assess the compatibility between a multivalent vaccine and a rabies vaccine when injected at two separate sites. Lack of interference was assessed by comparing serological response to viral components during one year following primary vaccination with vaccines administered alone or concomitantly. Antibody response to all tested components was comparable, irrespective of whether vaccines were administered individually or concurrently. Notably, the rabies vaccine induced very strong and protective seroconversion in dogs, whether it was administered concomitantly with the combo vaccine or not. This facilitates administration of rabies vaccine, which is a key factor for controlling the disease.
Asunto(s)
Enfermedades de los Perros/prevención & control , Vacunas Antirrábicas/inmunología , Vacunas Combinadas/inmunología , Infecciones por Adenoviridae/prevención & control , Infecciones por Adenoviridae/veterinaria , Animales , Anticuerpos Neutralizantes/inmunología , Vacunas Bacterianas/inmunología , Moquillo/prevención & control , Enfermedades de los Perros/virología , Perros , Femenino , Esquemas de Inmunización , Leptospirosis/prevención & control , Leptospirosis/veterinaria , Masculino , Infecciones por Parvoviridae/prevención & control , Infecciones por Parvoviridae/veterinaria , Rabia/prevención & control , Rabia/veterinaria , Infecciones por Respirovirus/prevención & control , Infecciones por Respirovirus/veterinaria , Seroconversión , Vacunación/veterinaria , Vacunas Atenuadas/inmunología , Vacunas Virales/inmunologíaRESUMEN
In a more and more regulated and socially pressured environment, the durable management of winery effluents must take into account their characteristics and their potential impact on their natural setting. The object of this exploratory study is to establish an inventory of the microbiological composition of winery effluents coming from different treatment systems. We have observed that winery effluents are charged with micro-organisms, by a factor that ranges from 10(5) to 10(8) UFC/ml, and that the level of "microbiological pollution" is independent of the type of system. The composition of the flora is closely tied to the time of year and therefore to winery activities, so certain micro-organisms will be favoured in certain periods and others will have a tendency to decrease. We have seen that from one year to another our observations remain identical; the flora equilibrium therefore occurs systematically and naturally. Faecal germs are found in very small quantities in winery effluent treatment systems. They represent minor sanitary risks. Good correlations were observed between some micro-organisms and some physical-chemical parameters (COD). It is, however, difficult to use these "easy-to-measure" parameters as reliable markers of certain microbial populations.