RESUMEN
The results of this survey show that 0.5 mg of ethynodiol diacetate (Femulen) is a reliable oral contraceptive with a pregnancy rate calculated by the Pearl Index of 0.52 per 100 women years. This is superior to the failure rates for both 0.075 mg dl norgestrel and 0.35mg norethisterone and approximates more closely with the claimed failure rates for combined oestrogen/progestogen preparations. There is no evidence which suggests that side effects occur with prolonged use of Femulen therapy.
Asunto(s)
Diacetato de Etinodiol , Embarazo , Adulto , Femenino , Humanos , Persona de Mediana EdadRESUMEN
In the results from this series ethynodiol diacetate ("Femulen") was found to be a reliable and acceptable oral contraceptive with a decreased risk of severe side-effects. A review of oral contraception (Jackson, 1973) supports the view that the progestogen-only pill has a useful part to play in modern oral contraception.
Asunto(s)
Diacetato de Etinodiol , Adolescente , Adulto , Ensayos Clínicos como Asunto , Evaluación de Medicamentos , Diacetato de Etinodiol/efectos adversos , Femenino , Humanos , Persona de Mediana Edad , EmbarazoRESUMEN
In a random crossover study in general practice, sixty patients with heart failure were given one week's maintenance treatment with the recommended dosage of Burinex K or Lasix+K. Burinex K appeared to be easier to swallow than the supplement tablets of Lasix+K although the differences were not significant. Patients showed a highly significant preference to take two tablets on one occasion (Burinex K) rather than two different types of tablet on three separate occasions (Lasix+K). Despite pharmacological arguments in favour of stimultaneous versus separate administration of potassium supplement and diuretic, patient acceptibility is of over-riding importance in the long-term.
Asunto(s)
Bumetanida/administración & dosificación , Diuréticos/administración & dosificación , Furosemida/administración & dosificación , Aceptación de la Atención de Salud , Potasio/administración & dosificación , Anciano , Bumetanida/uso terapéutico , Ensayos Clínicos como Asunto , Deglución , Preparaciones de Acción Retardada , Combinación de Medicamentos , Quimioterapia Combinada , Femenino , Furosemida/uso terapéutico , Insuficiencia Cardíaca/tratamiento farmacológico , Humanos , Masculino , Persona de Mediana Edad , Potasio/uso terapéutico , Encuestas y Cuestionarios , ComprimidosRESUMEN
Three hundred and twelve patients suffering from painful conditions were admitted to a multicentre, double-blind controlled trial, conducted in general practice in which five analgesics--floctafenine (Idarac), paracetamol, aspirin, dihydrocodeine and pentazocine--were compared. Overall ratings of analgesic effect placed floctafenine first in rank order. Floctafenine was statistically significantly superior in effect to pentazocine but not to the other three agents as far as doctor ratings were concerned; and superior to both pentazocine and dihydrocodeine in the opinion of patients. Fewer patients experienced side-effects on floctafenine than on the other four analgesics and this difference between floctafenine and pentazocine, and floctafenine and dihydrocodeine was statistically significant.