RESUMEN
Data on immunological changes that accompanied HCV infection are analyzed. Role of various viral proteins in induction of immune alterations leading to HCV persistence is reviewed. Possibility of association between pathogenic mechanisms (and outcomes) of hepatitis C and alteration of aminergic regulation mechanisms in the immune system as well as perspectives of further studies assessing the role NK and NKT cell in this process.
Asunto(s)
Hepacivirus/fisiología , Hepatitis C/inmunología , Células Asesinas Naturales/inmunología , Subgrupos Linfocitarios/inmunología , Aminas Biogénicas/metabolismo , Regulación hacia Abajo , Hepatitis C/virología , Hepatitis C Crónica/inmunología , Hepatitis C Crónica/fisiopatología , Humanos , Hígado/inmunología , Hígado/patología , Replicación ViralRESUMEN
Data about the dynamic changes in the peripheral blood cellular composition, a correlation between the quantities of circulating polinuclei and mononuclei of the blood and the activity of myeloperoxidase in granulocytes of Turkmen children, aged 4 to 16, with penetrating ocular injuries are presented in the paper with regard for age and ecological peculiarities of the region of residence.