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1.
J Anaesthesiol Clin Pharmacol ; 35(1): 114-118, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-31057252

RESUMEN

BACKGROUND AND AIMS: Buccal mucosa harvest for substitution urethroplasty can be painful, and may be associated with long-term complications such as perioral numbness, persistent difficulty with mouth opening, and change in salivary function. This study was designed to evaluate the efficacy of infraorbital nerve block (IOB) in relieving postoperative pain at the donor site of the buccal mucosal graft (BMG) and its associated morbidity at 30 days. MATERIAL AND METHODS: Thirty adults scheduled for BMG urethroplasty were enrolled in this study and were randomized to receive either no block group I (control) and IOB group II intraorally with 1 mL of 0.5% bupivacaine. Pain was assessed by visual analog scale, intraoral morbidity, and patient satisfaction in the immediate postoperative period. All patients were reviewed after 1 month for morbidity such as perioral numbness, pain on mastication, and tightness on mouth opening. Statistical analysis was done using Mann-Whitney's U and Chi-square tests. RESULTS: Median time to pain-free oral intake for liquids (group I: 2-5 days, group II: 1 day, P < 0.001) and solids (group I: 4 days, group II: 2 days, P < 0.001) was earlier in group II. At the follow-up after 1 month, one patient in group II and three patients in group I showed perioral numbness (P = 0.026), and five patients had pain on mastication in group I (P = 0.016). CONCLUSION: IOB is associated with postoperative analgesia and facilitation of early food intake, mitigating the morbidity of the donor site and provides satisfaction.

2.
J Endourol ; 23(5): 857-60, 2009 May.
Artículo en Inglés | MEDLINE | ID: mdl-19397429

RESUMEN

BACKGROUND AND PURPOSE: Percutaneous nephrolithotomy (PCNL) is a safe and effective endourologic procedure in patients with renal calculi. It is less morbid than open surgery. However, the patient complains of pain around the nephrostomy tube and demands for good postoperative analgesia. Skin infiltration with bupivacaine around the nephrostomy tube is not effective, so we hypothesize that peritubal infiltration of bupivacaine from renal capsule to the skin along the nephrostomy tract may alleviate postoperative pain. PATIENTS AND METHODS: A randomized controlled study was designed in 40 American Society of Anesthesiologists (ASA) grade I patients to assess the impact of peritubal bupivacaine infiltration with 23-gauge spinal needle along the nephrostomy tract after PCNL under fluoroscopic guidance. Patients were randomized to receive 20 mL of 0.25% bupivacaine in block group (n = 20) or no infiltration in control group (n = 20) at the conclusion of the procedure. Postoperative pain score and analgesic requirement for the first 24 hours were assessed by visual and dynamic visual analog scales second hourly. Rescue analgesia with injection tramadol Hcl 50-100 mg was given intravenously to a maximum total dose of 400 mg when pain score exceeded 4. RESULTS: Pain scores and analgesic requirement for the first 24 hours postoperatively were significantly lesser in the block group than in the control group of patients at all points of time and were statistically significant (p < 0.005). CONCLUSION: In this study a significant difference in the pain scores and analgesic requirement was noted in the two groups of patients. Peritubal infiltration of 0.25% bupivacaine solution is efficient in alleviating postoperative pain after PCNL.


Asunto(s)
Anestésicos Locales/uso terapéutico , Nefrostomía Percutánea/efectos adversos , Nefrostomía Percutánea/instrumentación , Dolor Postoperatorio/tratamiento farmacológico , Dolor Postoperatorio/etiología , Adulto , Demografía , Femenino , Humanos , Estimación de Kaplan-Meier , Masculino , Persona de Mediana Edad , Resultado del Tratamiento
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