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OBJECTIVES: This multicenter study aimed to evaluate cases of non-syndrome and syndromic odontogenic keratocyst, as well as cases of recurrence within these two groups. METHODS: This descriptive, analytical, retrospective cross-sectional study evaluated the sex, age and presence of multiple lesions in 1,169 individuals seen at 10 Brazilian oral and maxillofacial pathology centers. Of these, 1,341 odontogenic keratocysts were analyzed regarding clinical diagnosis, size, site, imaging appearance, signs and symptoms, type of biopsy, treatment, and recurrence. RESULTS: There was a similar distribution by sex. The median age of non-syndromic and syndromic patients was 32 and 17.5 years, respectively. The posterior mandible was the site most affected by small and large lesions in both groups and in recurrent cases. Unilocular lesions were more frequent, also in recurrent cases. Mainly small lesions showed this imaging appearance. Signs and symptoms were absent in most cases. Conservative treatment was the most frequent modality in all age groups, regardless of the patient's condition and recurrence. Recurrences were uncommon. CONCLUSION: This study showed a higher frequency of non-syndromic keratocysts in the population. Clinicopathological features related to the involvement of multiple sites, age, and recurrence may differ between syndromic and non-syndromic cases. Furthermore, we found an association between lesion size and some clinical features and between the time interval to recurrence and the syndromic spectrum. CLINICAL RELEVANCE: To contribute to a better understanding of the distribution and association between clinical, imaging, and sociodemographic characteristics in each spectrum of the lesion.
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Quistes Odontogénicos , Tumores Odontogénicos , Humanos , Estudios Retrospectivos , Brasil , Estudios Transversales , Quistes Odontogénicos/patologíaRESUMEN
The aim of this double-blind randomized study was to evaluate the biocompatibility of resin-modified glass ionomer cements (RMGIC) by means of morphological and immunohistochemical analyses. RMGICs were selected and divided into four groups: Group CK (Crosslink Orthodontic Band Cement); Group RS (Resilience Light Cure Band Cement) Group RMO (RMO Band Cement), Group TP (Transbond Plus Light Cure Band), and Group C (Control-polyethylene). The materials were implanted in rat subcutaneous tissues, randomly selected for this study. After time intervals of 7, 15, and 30 days the tissues were submitted to morphological analysis. In immunohistochemical analysis, the immuno-marking of antibody CD68 was evaluated. The results obtained were statistically analyzed by the Kruskal-Wallis and Dunn tests (p < .05). In the morphological analysis after 7 days, Groups RS, RMO and TP showed more intense inflammatory infiltrate (p = .004) and only Group RMO presented greater intensity of multinucleated giant cells (p = .027). In the immunohistochemical analysis, Groups RMO and RS were observed to present a larger quantity of CD68+ (p = .004) in the time interval of 7 days and only Group RMO presented statistically significant difference for this parameter after 15 days (p = .026). In the time interval of 30 days, Group RMO presented the largest quantity of multinucleated giant cells (p < .004). The RMGICS Crosslink and Transbond Plus provided significantly better tissue biocompatibility than the Resilience and RMO Cements.
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Materiales Biocompatibles/química , Bisfenol A Glicidil Metacrilato/análisis , Cementos Dentales/análisis , Cementos de Resina/química , Animales , Antígenos CD , Antígenos de Diferenciación Mielomonocítica , Materiales Biocompatibles/análisis , Bisfenol A Glicidil Metacrilato/química , Recubrimiento Dental Adhesivo , Cementos Dentales/química , Método Doble Ciego , Células Gigantes/inmunología , Células Gigantes/ultraestructura , Humanos , Inmunohistoquímica , Inflamación , Macrófagos/inmunología , Macrófagos/fisiología , Masculino , Ensayo de Materiales/métodos , Distribución Aleatoria , Ratas , Ratas Wistar , Cementos de Resina/análisis , Tejido Subcutáneo/anatomía & histología , Tejido Subcutáneo/inmunología , Tejido Subcutáneo/fisiologíaRESUMEN
Introdução: a terapia com laser tem sido utilizada com muito êxito na clínica odontológica e é uma excelente opção para cuidados de saúde. Objetivo: identificar no Norte/Nordeste do Brasil o número de dentistas especializados en raios laser e identificar, dentro do territorio brasileiro, as regiões onde há maior demanda de cursos de capacitação em laserterapia. Métodos: estudo descritivo com base nas consultas de dados secundários disponíveis no site do Conselho Federal de Odontologia, na secção de serviços e consultas, em 2013. Os resultados foram avaliados pelos testes do chi-quadrado e exato de Fisher (nível de significância de 5 porcento). Resultados: a amostra do estudo foi formada por 29 profissionais. Nas regiões analisadas, a maioria dos profissionais que possuiam a especialização em laserterapia eran clínicos gerais (sem especialização). Verificpu-se que a região sudeste se destaca pela maior disponibilidade de cursos certificados laserterapia, seguido pelo sul e pelo norte. O nordeste não apresenta nenhum curso em laserterapia, embora tenha mais profissionais especializados que no norte. O laser não deve representar apenas um dispositivo novo na clínica odontológica, mas sim, como uma nova filosofia terapêutica, que permite una interação biofísica entre a luz e o tecido biológico, o qual favorece um melhor tratamento e uma melhor qualidade de vida dos pacientes. Conclusões: uma maior quantidade de profissionais especializados se encontram na região sul e sudeste do Brasil, porém já é possível notar um aumento deste número no nordeste(AU)
Introducción: la terapia con rayos láser se ha utilizado con mucho éxito en la clínica dental, actualmente constituye una excelente opción para la asistencia sanitaria. Objetivo: identificar en el norte/noreste de Brasil el número de dentistas especializados en rayos láser y identificar, dentro del territorio brasileño, las regiones donde hay mayor demanda de cursos de capacitación de terapia con rayos. Métodos: estudio descriptivo basado en las consultas de datos secundarios disponibles en el Consejo Federal de Odontología del sitio, la sección de servicios y consultas, en 2013. Los resultados se evaluaron mediante la prueba de chi cuadrado y la prueba exacta de Fisher (nivel de significación del 5 por ciento). Resultados: la muestra estuvo conformada por 29 profesionales. En las regiones analizadas, la mayoría de los profesionales que poseen la especialización en terapia con rayos láser son médicos generales (no especializados). Se encontró que la región sureste destaca por una mayor disponibilidad de cursos certificados en la terapia con rayos láser, seguido por el sur y el norte. El noreste no muestra ningún curso en la terapia con rayos laser, aunque hay más profesionales cualificados que en el norte. El rayo láser no debe definirse solo como un dispositivo nuevo en la clínica dental, sino como una nueva filosofía terapéutica, que permite una interacción biofísica entre la luz y el tejido biológico, lo cual favorece un mejor tratamiento y una mejor calidad de vida de los pacientes. Conclusiones: una mayor cantidad de profesionales especializados se encuentra en la región sur y sureste de Brasil pero ya es posible notar una ampliación de este número en el noreste(AU)
Introduction: laser therapy has been used with great success in dental clinics, and constitutes an excellent option in current health care. Objective: determine the number of dentists specializing in laser therapy in the north / northeast of Brazil and identify the regions in the Brazilian territory where there is a greater demand for courses on laser therapy. Methods: adescriptive study was conducted based on the examination of secondary data available from the Brazilian Federal Council of Dentistry of the area, the services section and consultations, in the year 2013. Results were evaluated with the chi-square test and Fisher's exact test (significance level of 5 percent). Results: the sample was composed of 29 professionals. In the regions analyzed, most professionals with specialization in laser therapy are general, non-specialized practitioners. It was found that the southeast stands out for its greater availability of certified courses on laser therapy, followed by the south and the north. No course about laser therapy was found in the northeast, despite the fact that there are more qualified professionals in that region than in the north. Laser therapy should not be defined as a new device in dental practice, but as a new therapeutic philosophy allowing biophysical interaction between light and biological tissue, thus providing better treatment and improving the quality of life of patients. Conclusions: alarger number of specialized professionals may be found in the south and southeast of Brazil, but an increase in their number is already noticeable in the northeast(AU)
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Humanos , Especialidades Odontológicas/métodos , Terapia por Láser/efectos adversos , Brasil , Epidemiología DescriptivaRESUMEN
O problema do câncer no Brasil ganha relevância particular pelo perfil epidemiológico que essa doença vem apresentando. Embora se perceba um declínio nas taxas de mortalidade por câncer da cavidade oral, tem-se presenciado, ultimamente, um aumento desse número em pacientes jovens. Objetivos: Traçar o perfil dos estudos em odontologia desenvolvidos no Brasil durante os últimos cinco anos (2007-2011) no que diz respeito ao carcinoma de células escamosas oral. Métodos: Realizou-se uma revisão sistemática dos trabalhos sobre câncer oral apresentados nas reuniões da Sociedade Brasileira de Pesquisa em Odontologia (SBPqO) no período de 2007 a 2011. As buscas com os termos carcinoma de células escamosas, carcinoma epidermoide, carcinoma espinocelular e oral squamous cell carcinoma resultaram em 199 resumos. Os dados foram organizados e apresentados por meio da estatística descritiva. Resultados: Obteve-se um pico de trabalhos no ano de 2008; concentração da produção científica na região Sudeste, porém também pôde se verificar uma alta contribuição do estado do Rio Grande do Norte; predomínio de estudos de natureza observacional e do tipo transversal em detrimento aos de intervenção e de corte longitudinal. Conclusão: As pesquisas sobre o carcinoma de células escamosas oral constituem um percentual relativamente pequeno da produção científica odontológica brasileira dos últimos cinco anos. A priorização de pesquisas observacionais interrrompe a continuidade do conhecimento científico e acumula informações que não melhoram as condições terapêuticas e prognósticas dos pacientes com câncer oral.
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Este estudio epidemiológico evaluó la prevalencia de anormalidades bucales y caries dental en pacientes portadores de Síndrome de Down. La muestra fue compuesta por 48 pacientes con edades entre 2 y 18 años, siendo analizada las variables: sexo; edad, presencia y tipo de alteraciones bucales; frecuencia y forma de cepillado; visita al cirujano odontólogo y prevalencia de caries dental. Los datos fueron analizados descriptivamente con el Software Epi info 3.7 y presentados a través de estadística descriptiva. Análisis bivariado fue realizado a través del test Chi-cuadrado de Pearson (p<0,05). Del total examinado, 58.3% eran del sexo másculino, con predominio de las edades entre 2 a 10 años (66,7%). Fue verificado que 83.8% de la muestra tenía lengua fisurada y 35.4% poseía microdoncia. La frecuencia diaria de cepillado fue de dos veces al día (85,4%), siendo realizada bajo la supervisión de los padres (50,0%). Una única visita anual al cirujano odontólogo fue relatada por 85.7% de los evaluados. El valor medio del CPO-D fue de 5,3, con predominio de caries en el sexo femenino (75,0%) y entre las edades de 11 a 18 años (93,8%). Concluyese que la muestra estudiada presenta una alta prevalencia de caries y un conjunto de manifestaciones bucales peculiares al individuo portador del Síndrome de Down
This epidemiological study offered to evaluate the prevalence of mouth anomalies and dentario caries in patients with Down syndrome. The sample was composed of 48 patients aging from 2 to 18 years, being the following variables evaluated: sex, age, presence and types of mouth alterations; frequency and the way they brush; consult with the dentario surgeon and prevalence of dentario cavity. The data were organized with the aid of a 3.7 Epi info Software and presented by means of descriptive statistics. The bi-varied analysis was carried out through Pearson's Qui-square test (p<0.05). Out of the total examined, 58.3% were males, aging predominantly 2-10 years (66.7%). It was verified that 83.8% of the sample had fissured tongue, and 35.4% had microdonty. As to the brushing of the teeth, the daily frequency of twice a day prevailed (85.4%), being conducted under the parents' supervision (50.0%). A single annual consult with the dentario surgeon was stated by 85.7% of the subjects. The average value of DMF-T was 5.3, with predominance of dentario caries in females (75.0%) and in the patients aging 11-18 years (93.8%). It was concluded that the sample studied presents a high prevalence of dentario caries and an array of peculiar mouth manifestations to the person with Down syndrome
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Humanos , Masculino , Femenino , Preescolar , Niño , Adolescente , Caries Dental/prevención & control , Síndrome de Down , Enfermedades de la Boca/patología , Enfermedades de la Boca/prevención & control , Síndrome de Down/etiología , Odontología PediátricaRESUMEN
Objetivo: Realizar una evaluación epidemiológica de los quistes odontogénicos en pacientes de 0 a 14 años de edad, verificando cuáles son las lesiones de mayor incidencia entre estas edades. Métodos: Fueron evaluadas 100 fichas histopatológicas de lesiones diagnosticadas como quistes de naturaleza odontogénica, enfatizando las características clínicas (género, edad, tipo de lesión quística, localización anatómica y tamaño de la lesión) y radiográficas. Resultados: Fue observado que el género masculino, con edad media de 9, 78 años, así como las regiones posterior de mandíbula y anterior de la maxila fueron más comprometidos. El quiste dentígero fue la lesión más común, seguida del quiste radicular. Se observó además, que en la muestra evaluada el aspecto radiográfico unilocular y las lesiones asintomáticas fueron las más frecuentes. Conclusiones: Se concluyó que es muy importante realizar este tipo de estudios, una vez que a través de ellos podemos conocer la frecuencia e incidencia de diversas lesiones, principalmente en pacientes pediátricos, en los cuales poco se conoce sobre la prevalencia de las lesiones quísticas de los maxilares.
Objective: To realize an epidemiologic survey of odontogenic cysts in patients from 0 to 14 years old in order to find out the most prevalent lesions of each age period. Methods: 100 histopathologic files of lesions diagnosed as cysts of odontogenic origin were retrieved emphasing their clinic (cystic lesion pattern, gender, age, anatomical site and lesion lenght) and radiographic features, which the surgical specimens were forwarded for the Oral Pathology Service of UFRN. Results: It could be identified that either the male gender, with an age average of 9,78 years, or the mandible posterior and the anterior maxilla region were more involved. Dentigerous cyst was the most prevalent lesions, followed by the radicular cyst. Moreover, a unilocular radiolucence and asymptomatic lesions were more common in the sample. Conclusions: To sum up, it can be infered the outstanding relevance of studies like the present since that it is through than that it can be reached the knowledge of the frequency and incidence of several lesions, especially in paediatric patients in as much as the few knowledge of the cystic lesion prevalence in their jaws.
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Humanos , Masculino , Femenino , Recién Nacido , Lactante , Preescolar , Niño , Adolescente , Odontología Pediátrica/estadística & datos numéricos , Quistes Maxilomandibulares/diagnóstico , Quistes Maxilomandibulares/epidemiología , Quistes Maxilomandibulares/patología , Distribución por Edad y Sexo , Epidemiología Descriptiva , Quiste Odontogénico Calcificado/diagnóstico , Quiste Odontogénico Calcificado/patología , Quistes Odontogénicos/diagnóstico , Quistes Odontogénicos/patología , Interpretación Estadística de Datos , Traumatismos de los Dientes/complicacionesRESUMEN
El papel de la respuesta inmunológica en la patogénesis de la enfermedad periodontal constituye tema constante de investigación por diversos autores. En el presente trabajo se propuso realizar un análisis inmunohistoquímico de la densidad y del patrón de distribución de la población celular macrofágica utilizando el anticuerpo anti-CD68 en 17 casos de gingivitis crónica y 25 de periodontitis crónica. Las células CD68+ se distribuyeron difusamente por todo el tejido conectivo. El análisis estadístico reveló diferencia significativa entre los especimenes estudiados (p < 0,05), siendo la densidad de las células macrofágicas mayor en la gingivitis crónica. Los resultados observados sugieren una mayor participación de esas células en la patogénesis de la gingivitis.
The important function of immunological reaction in periodontal disease has been studied by several reports. In order to achieve contributive information to the knowledge of the pathogeny of this disease, an immunohistochemical analysis of the density and distribution of macrophagic cells was realized using anti-CD68 antibody in 17 cases of chronic gingivitis and 25 cases of chronic periodontitis. The CD68+ cells exhibited diffuse distribution in the connective tissue. The statistical analysis shown differences in relation to the density of this cells between the groups (p < 0,05), where the density of macrophacgic cells was higher in the chronic gingivitis. Its results can infer that the macrophagic cells has greated role in the pathogenesis of gingivitis.