RESUMEN
Cefazolin is an antibiotic recommended for infection prevention in total hip arthroplasty (THA). However, the dosing regimen necessary to achieve therapeutic concentrations in obese patients remains unclear. The aim of this study was to conduct a population analysis of cefazolin pharmacokinetics (PK) and assess whether cefazolin administration should be weight adapted in THA. Adult patients undergoing THA surgery received an injection of 2000 mg of cefazolin, doubled in the case of BMI > 35 kg/m2 and total body weight > 100 kg. A population PK study was conducted to quantify cefazolin exposure over time compared to the therapeutic concentration threshold. A total of 484 cefazolin measurements were acquired in 100 patients, of whom 29% were obese. A 2-compartment model best fitted the data, and creatinine clearance determined interpatient variability in elimination clearance. Our PK simulations using a 2000 mg cefazolin bolus showed that cefazolin concentrations remained above the threshold throughout surgery, regardless of weight or renal function. A 2000 mg cefazolin single injection without adaptation to weight or renal function and without intraoperative reinjection was efficient in maintaining therapeutic concentrations throughout surgery. The optimal target concentration and necessary duration of its maintenance remain unclear.
Asunto(s)
Antibacterianos/farmacocinética , Cefazolina/farmacocinética , Modelos Teóricos , Adulto , Anciano , Anciano de 80 o más Años , Algoritmos , Antibacterianos/administración & dosificación , Profilaxis Antibiótica , Artroplastia de Reemplazo de Cadera/efectos adversos , Artroplastia de Reemplazo de Cadera/métodos , Cefazolina/administración & dosificación , Simulación por Computador , Femenino , Humanos , Masculino , Persona de Mediana Edad , Programas Informáticos , Infección de la Herida Quirúrgica/prevención & control , Adulto JovenRESUMEN
INTRODUCTION: Repair is indicated for tears in non-degenerative menisci. The literature reports a 15% failure rate for all-inside repair. The aim of the present study was to determine prognostic factors for failure of all-inside meniscal repair. The study hypothesis was that epidemiological, clinical and surgical factors affect success. MATERIAL AND METHODS: A retrospective study included 87 meniscal repair procedures, with or without anterior cruciate ligament (ACL) tear. Lesions were located in red-red or red-white zones. After freshening, repair comprised an all-inside arthroscopic technique using the FasT-Fix® system (Smith & Nephew), with (70.1%) or without ligament reconstruction; all ACL tears were reconstructed. Preoperative data comprised: age, gender, smoking status, sports activity, trauma-to-surgery time, body mass index (BMI), frontal morphotype, and IKDC score. Intra- and postoperative data comprised: meniscal lesion characteristics, location, number of sutures, type of ACL reconstruction, presence of chondropathy, authorized postoperative ranges of motion, and IKDC score. Failure was defined by secondary meniscectomy. RESULTS: At 31 months' follow-up, there were 13 failures (15%). Mean postoperative IKDC score was 88.19 (range: 64.37-98.95). Bucket-handle lesion (P=0.006) and BMI>25 (P=0.014) emerged as significant factors of poor prognosis. DISCUSSION: The present failure rate matched those reported in the literature. The more extensive the lesion, the higher the risk of failure. High BMI incurs mechanical stresses that increase the risk of failure. LEVEL OF EVIDENCE: IV, retrospective cohort study.
Asunto(s)
Artroscopía/métodos , Lesiones de Menisco Tibial/cirugía , Adolescente , Adulto , Lesiones del Ligamento Cruzado Anterior/complicaciones , Lesiones del Ligamento Cruzado Anterior/cirugía , Reconstrucción del Ligamento Cruzado Anterior , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Pronóstico , Estudios Retrospectivos , Lesiones de Menisco Tibial/complicaciones , Insuficiencia del Tratamiento , Adulto JovenRESUMEN
INTRODUCTION: Patellar instability is a frequent cause of total knee arthroplasty (TKA) failure. In cases of post-arthroplasty patellar instability, the medial structures may be damaged. The objective of this study was to study the effectiveness of medial patellofemoral ligament (MPFL) reconstruction. We hypothesized that MPFL reconstruction will effectively realign the patella, making it a viable treatment option for managing post-arthroplasty patellar instability. MATERIAL AND METHODS: In this retrospective study of six patients treated by four different surgeons, patients were included if they had a recurring or permanent patellar dislocation after undergoing TKA. Patients were excluded if the patellar instability was painful but did not result in dislocation. Each patient underwent MPFL reconstruction using the gracilis; additional procedures could be performed depending on the diagnosis. One patient required TKA revision because of an abnormally rotated femoral implant. The main outcome measure was the non-recurrence of the dislocation. The IKDC and Kujala functional scores, joint range of motion and patellar tilt on X-rays were analyzed preoperatively and at the last follow-up. RESULTS: At a mean follow-up of 23 months (6-46), none of the patients experienced a recurrence of the patellar dislocation. Only one patient had no improvements in the functional outcome scores. The patellar tilt was reduced in all patients. CONCLUSION: MPFL reconstruction-in isolation or with femoral component revision-is effective at treating post-arthroplasty patellar instability. It has its place in the treatment of patellar dislocation following TKA and its indications must be based on exact analysis of the reasons for the instability. LEVEL OF EVIDENCE: IV - Retrospective cohort study.
Asunto(s)
Artroplastia de Reemplazo de Rodilla/efectos adversos , Inestabilidad de la Articulación/prevención & control , Ligamentos Articulares/cirugía , Luxación de la Rótula/prevención & control , Tendones/trasplante , Anciano , Anciano de 80 o más Años , Femenino , Estudios de Seguimiento , Humanos , Masculino , Luxación de la Rótula/etiología , Articulación Patelofemoral/cirugía , Estudios RetrospectivosRESUMEN
AIMS: The purpose of this study was to analyse the biomechanics of walking, through the ground reaction forces (GRF) measured, after first metatarsal osteotomy or metatarsophalangeal joint (MTP) arthrodesis. PATIENTS AND METHODS: A total of 19 patients underwent a Scarf osteotomy (50.3 years, standard deviation (sd) 12.3) and 18 underwent an arthrodesis (56.2 years, sd 6.5). Clinical and radiographical data as well as the American Orthopaedic Foot and Ankle Society (AOFAS) scores were determined. GRF were measured using an instrumented treadmill. A two-way model of analysis of variance (ANOVA) was used to determine the effects of surgery on biomechanical parameters of walking, particularly propulsion. RESULTS: Epidemiological, radiographical and clinical data were comparable in the two groups and better restoration of propulsive function was found after osteotomy as shown by ANOVA (two way: surgery × foot) with a surgery effect on vertical forces (p < 0.01) and a foot effect on anteroposterior impulse (p = 0.01). CONCLUSION: Patients who underwent Scarf osteotomy had a gait pattern similar to that of their non-operated foot, whereas those who underwent arthrodesis of the first (metatarsophalangeal) MTP joint did not totally recover the propulsive forces of the forefoot. TAKE HOME MESSAGE: The main findings of this study were that after surgical correction for hallux valgus, patients who underwent scarf osteotomy had a gait pattern similar to that of their non-operated foot in terms of forefoot propulsive forces (Fz3, Iy2), whereas those who underwent arthrodesis of the first MTP joint had not. Cite this article: Bone Joint J 2016;98-B:641-6.
Asunto(s)
Artrodesis , Antepié Humano/fisiopatología , Marcha/fisiología , Hallux Valgus/fisiopatología , Hallux Valgus/cirugía , Osteotomía , Fenómenos Biomecánicos/fisiología , Estudios Transversales , Femenino , Humanos , Masculino , Huesos Metatarsianos/cirugía , Articulación Metatarsofalángica/cirugía , Persona de Mediana Edad , Caminata/fisiologíaRESUMEN
Gait pattern alterations were previously reported in association with objective patellar instability (OPI). Gait pattern comparison between a series of patients having undergone medial patellofemoral ligament (MPFL) reconstruction and a sample of control subjects. Thirty patients at 6 months postoperatively after MPFL reconstruction and thirty control subjects were enrolled in the study for a clinical and biomechanical assessment including gait analysis at three selected walking rates using the GAITRite(®) system. The mean raw IKDC score was 73 (± 19), and the mean Kujala knee function was 84 (± 17.5). The study of gait did not demonstrate any significant difference between the two groups at a normal and fast walking rate. At a 10 km/h running speed, the single-support phase was significantly shortened by a mean 2.33% (p < 0.05), the swing phase by a mean 2.64% (p < 0.05) and the double-support phase by a mean 3.49% (p < 0.05) on the operated side. MPFL reconstruction reported good midterm functional and clinical results in the management of OPI. At 6 months postoperatively, the patient gait pattern was similar to that observed in healthy subjects at a normal and fast walking speed. However, our study revealed persistent gait abnormalities at a 10 km/h running speed. These gait alterations seemed to be related to the ligament reconstruction in itself due to the higher strain applied on the reconstructed MPFL during running cycle (10 km/h). Level of evidence IV.
Asunto(s)
Marcha/fisiología , Inestabilidad de la Articulación/cirugía , Articulación de la Rodilla/cirugía , Ligamentos Articulares/cirugía , Luxación de la Rótula/cirugía , Articulación Patelofemoral/cirugía , Adolescente , Adulto , Femenino , Humanos , Inestabilidad de la Articulación/fisiopatología , Articulación de la Rodilla/fisiopatología , Ligamentos Articulares/fisiopatología , Masculino , Luxación de la Rótula/fisiopatología , Articulación Patelofemoral/fisiopatología , Procedimientos de Cirugía Plástica , Recuperación de la Función , Recurrencia , Caminata/fisiología , Adulto JovenRESUMEN
BACKGROUND: The medial patellofemoral ligament (MPFL) is the most commonly injured structure in patients with objective patellar instability. The objective of this study was to prospectively evaluate the clinical and radiographic results of MPFL reconstruction in 50 patients with chronic patellar instability. METHODS: Fifty patients with chronic patellar instability, aged 15-39 years, were included. The MPFL was reconstructed using a free gracilis autograft tendon. Two anchors were used for patellar fixation, and femoral fixation was achieved with an interference screw placed into a tunnel between the adductor tubercle and medial epicondyle. The graft was tensioned to 10 N with the knee in 30° flexion. IKDC and Kujala scores were assessed pre- and post-operatively. Patellar tilt was measured from CT scans with the quadriceps relaxed and contracted, both pre- and post-operatively. RESULTS: The follow-up period was 7 to 44 months (mean: 25 months, SD 10.3). The mean raw IKDC score increased from 51.5 preoperatively to 71.7 at last follow-up, the mean overall IKDC score increased from 38.5 to 61.7 and the Kujala score increased from 48.3 to 82.4. On CT scans, the mean patellar tilt went from 24° to 16.2° with the quadriceps relaxed and 27.7° to 18.1° in contraction. No recurrent dislocation was observed. CONCLUSION: This technique of MPFL reconstruction provided significant improvements in IKDC and Kujala scores and significant reduction in patellar tilt. No recurrent dislocations were observed during the study period.
Asunto(s)
Inestabilidad de la Articulación/cirugía , Ligamento Rotuliano/trasplante , Articulación Patelofemoral/cirugía , Procedimientos de Cirugía Plástica/métodos , Músculo Cuádriceps/cirugía , Rango del Movimiento Articular/fisiología , Adolescente , Adulto , Autoinjertos , Femenino , Humanos , Inestabilidad de la Articulación/diagnóstico , Inestabilidad de la Articulación/fisiopatología , Masculino , Articulación Patelofemoral/fisiopatología , Estudios Prospectivos , Tomografía Computarizada por Rayos X , Adulto JovenRESUMEN
BACKGROUND: The knee joint is vulnerable to various injuries and degenerative conditions, potentially leading to functional instability. Usual treatments involve knee orthoses to support the joint. However, the level of mechanical action of these devices remains controversial despite high prescription and demand. METHODS: The mechanical ability of three commercial hinged knee braces and one sleeve to prevent a static drawer was evaluated using a GNRB arthrometer. The testing of both pathological and healthy joints was performed on 16 patients with documented injuries involving the ACL, and an original method allowed decoupling the contribution of the brace. RESULTS: The mean stiffness of the three hinged braces ranged between 2.0 and 7.1 N/mm. The most efficient brace was able to exert a restraining force on the joint equivalent to the one exerted by a healthy ACL, up to a 2.8 mm anterior displacement of the tibia. For higher anterior displacements, the restraining force of the brace dropped below the level of action of the intact ACL because of the particular non-linear behaviour of this structure. Finally, the most efficient brace was found to vary from subject to subject. CONCLUSIONS: This study confirmed that fabric-based knee braces may effectively replace the passive mechanical role of the ACL within the low stiffness region of this structure. Although bracing may have other benefits (e.g., proprioception), this shows that they act as an effective passive restraint to low grade anterior laxities. Besides, a high patient-specificity of their effects highlighted the need of personalised objective testing for brace selection.
Asunto(s)
Lesiones del Ligamento Cruzado Anterior , Artrometría Articular/métodos , Tirantes , Inestabilidad de la Articulación/terapia , Adolescente , Adulto , Fenómenos Biomecánicos/fisiología , Femenino , Humanos , Inestabilidad de la Articulación/fisiopatología , Articulación de la Rodilla/fisiopatología , Masculino , Persona de Mediana Edad , Adulto JovenRESUMEN
INTRODUCTION: Among the numerous techniques available, medial patellofemoral ligament (MPFL) reconstruction is increasingly used for the surgical treatment of objective patellar instability. The main objective of the present study was to assess efficacy in preventing recurrence of patellar dislocation and in correcting radiographic patellar tilt. The study hypothesis was that MPFL reconstruction, isolated or with associated bone surgery, by restoring "favorable" graft anisometry, provides a good trade-off between patellar stability and absence of postoperative stiffness. MATERIALS AND METHODS: Eighty-seven patients (90 reconstructions) presenting with objective patellar instability were prospectively included. The standardized procedure comprised MPFL reconstruction using the gracilis tendon. Femoral fixation used an interference screw in a blind tunnel between the adductor magnus tubercle and the medial epicondyle; patellar fixation used 2 anchors. Complementary distal bone graft was associated in 21 patients due to a preoperative tibial tubercle-trochlear groove (TT-TG) distance exceeding 20mm or to patella alta. Functional IKDC and Kujala scores and radiographic measurement of patellar tilt and femoral tunnel position were assessed preoperatively and at end of follow-up. RESULTS: Mean follow-up was 24.3months (range, 6-49months). Three patients showed recurrence of patellar dislocation. Mean Kujala score rose from 53.88 preoperatively to 86.24 postoperatively, and mean real IKDC score from 45.15 to 73.92 (P<0.001). Patellar tilt decreased significantly between pre- and postoperative X-ray (P<0.001). DISCUSSION: MPFL gracilis reconstruction provides good clinical results and good radiologic correction of patellar tilt, making it a technique of choice in the treatment of objective patellar instability. LEVEL OF EVIDENCE: Level IV. Retrospective case series study.
Asunto(s)
Artrografía/métodos , Inestabilidad de la Articulación/cirugía , Ligamentos Articulares/cirugía , Procedimientos Ortopédicos/métodos , Articulación Patelofemoral/diagnóstico por imagen , Procedimientos de Cirugía Plástica/métodos , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Niño , Femenino , Estudios de Seguimiento , Humanos , Inestabilidad de la Articulación/diagnóstico por imagen , Inestabilidad de la Articulación/fisiopatología , Masculino , Persona de Mediana Edad , Articulación Patelofemoral/fisiopatología , Articulación Patelofemoral/cirugía , Estudios Prospectivos , Rango del Movimiento Articular/fisiología , Factores de Tiempo , Resultado del Tratamiento , Adulto JovenRESUMEN
INTRODUCTION: Hemi-Castaing ligamentoplasty is a treatment for chronic ankle instability, accused of weakening a powerful stabilizing muscle: the peroneus brevis. OBJECTIVES: To assess proprioceptive and muscular impairment following hemi-Castaing and impact on postural control. METHODOLOGY: A retrospective series of 21 patients underwent clinical (Karlsson, AOFAS) and proprioceptive assessment with isokinetic assessment (evertors and invertors) on a Con-Trex dynamometer and postural assessment on a Win-Posturo force platform, at a minimum 6 months postsurgery. RESULTS: At a mean 18 months' follow-up, mean Karlsson score was 84 and AOFAS score 88. Ankle joint position sense error was less on the operated than on the healthy side. Evertor strength deficit with respect to the healthy side was 4.7% (ns) at 30°/s and 5.7% (ns) at 120°/s in concentric mode and 6.6% (ns) in excentric mode. After surgery, the evertor/invertor ratio was >1 (in favor of the evertors). Postural values were significantly higher for the operated ankle. DISCUSSION-CONCLUSION: Hemi-Castaing ligamentoplasty provided excellent clinical and functional results. It did not disturb the agonist/antagonist balance of the ankle muscles, and harvesting a half peroneus brevis did not impair evertor isokinetic force. Joint position sense was not impaired; indeed, deficits with respect to the contralateral side showed improvement. LEVEL OF EVIDENCE: Retrospective study.
Asunto(s)
Articulación del Tobillo/fisiopatología , Inestabilidad de la Articulación/diagnóstico , Inestabilidad de la Articulación/fisiopatología , Ligamentos Laterales del Tobillo/cirugía , Músculo Esquelético/fisiopatología , Propiocepción/fisiología , Adulto , Articulación del Tobillo/cirugía , Femenino , Estudios de Seguimiento , Humanos , Inestabilidad de la Articulación/cirugía , Cinética , Ligamentos Laterales del Tobillo/fisiopatología , Masculino , Persona de Mediana Edad , Dinamómetro de Fuerza Muscular , Procedimientos Ortopédicos/métodos , Equilibrio Postural/fisiología , Estudios Retrospectivos , Resultado del Tratamiento , Adulto JovenRESUMEN
INTRODUCTION: Partial anterior cruciate ligament (ACL) ruptures are common. The ability to distinguish between various types of ACL ruptures preoperatively would allow surgeons to choose the most appropriate surgical treatment. HYPOTHESIS: A partial ACL rupture can be diagnosed preoperatively. MATERIAL AND METHODS: The goal of this single-center, prospective study was to establish correlations between various macroscopic types of ACL ruptures determined by arthroscopy with data from clinical examination, knee laxity measurements (GnRB(®)) and magnetic resonance imaging (MRI). The 49 patients included over a six-month period had a diagnosis of ACL rupture based on the clinical examination. Four arthroscopy categories were defined based on the French Arthroscopy Society (SFA) classification. Each patient had their knee laxity measured, a preoperative MRI performed and a clinical exam done in the operating room before the procedure. RESULTS: During arthroscopy, the ACL was described as "Complete tear" in 23 of 49 patients, "Healed onto PCL" in 12, "Posterolateral bundle preserved" in 14 and "Healed into notch" in none of the patients. The clinical exam alone could not discriminate between the various types of ruptures (P>0.05). With MRI, the sensitivity was 84% and the specificity was 92% for partial ACL rupture. There was a strong correlation between MRI and the various arthroscopy groups (P<0.05). There was a significant difference (P<0.05) between partial and complete ruptures in terms of knee laxity. CONCLUSION: This study helped define the relationships between arthroscopy findings, MRI findings and knee laxity measurements. It is feasible to make a preoperative diagnosis of partial ACL rupture. LEVEL OF EVIDENCE: Level IV, prospective cohort study.
Asunto(s)
Lesiones del Ligamento Cruzado Anterior , Reconstrucción del Ligamento Cruzado Anterior/métodos , Artroscopía/métodos , Traumatismos de la Rodilla/diagnóstico , Imagen por Resonancia Magnética , Adulto , Femenino , Estudios de Seguimiento , Humanos , Traumatismos de la Rodilla/cirugía , Masculino , Estudios Prospectivos , Reproducibilidad de los Resultados , Rotura , Índices de Gravedad del TraumaRESUMEN
PURPOSE: The influence of the medial patellar ligamentous structures on patellar tracking has rarely been studied. Thus the main purpose of this cadaveric biomechanical study was to determine the influence of the medial patellofemoral (MPFL), medial patellomeniscal (MPML) and medial patellotibial (MPTL) ligaments on the three-dimensional patellar tracking during knee flexion. This study was conducted using a validated cadaveric optoelectronic protocol for analysis of patellar kinematics. METHODS: For each cadaveric knee study, four successive acquisitions were performed; first was studied patellar tracking in healthy knees, then the junction between MPFL and vastus medialis obliquus (VMO) was sectioned, the MPFL was released at its patellar attachment and finally was released the insertion of the MPML and MPTL. RESULTS: In this study, the MPFL accounts for 50-60% of the medial stabilization forces of the lateral patellar shift during patellar engagement in the femoral trochlea. This work confirm and clarify the role of the MPFL as the primary stabilizer of the patella during the initial 30° of knee flexion. Moreover, this study shows no significant results regarding the stabilizing action of the VMO on the patella during knee flexion. CONCLUSION: This in vitro study, conducted with an experimental protocol previously validated in the literature, helps quantify the actions of the MPFL, the VMO, and the MPML/MPTL respectively, and identify areas of joint motion where these structures have the most significant influence. This confirms the importance of reconstruction in the treatment of chronic patellar instability. During its reconstruction, care should be taken to adjust the MPFL balance during the initial 20°-30° of flexion.
Asunto(s)
Articulación de la Rodilla/fisiología , Ligamentos Articulares/fisiología , Rótula/fisiología , Fenómenos Biomecánicos , Humanos , Técnicas In VitroRESUMEN
INTRODUCTION: The main causes of total hip arthroplasty (THA) revisions are loosening and instability. Dual mobility cups were introduced to prevent instability, but their behavior during revisions with acetabular reconstruction has not been assessed. HYPOTHESES: Use of a dual mobility cup cemented in a acetabular reconstruction cage device limits the risk of instability and does not hinder the acetabular fixation during THA revisions. OBJECTIVES: The objective of this study was to test this hypothesis on a retrospective series of 96 revisions. PATIENTS AND METHODS: At a mean follow-up of 41 months (range, 1-101 months), we analyzed a continuous series of 96 revisions using a reconstruction device (70 Kerboull™ cross-plates, six Burch-Schneider™ antiprotrusio cages, 20 custom-fit Novae ARM™ cages associated in all cases with a Novae Stick dual mobility cup cemented into the cage). Fifteen patients died at a mean follow-up of 22 months (range, 1-66 months) and four patients were lost to follow-up at a mean follow-up of 16 months (range, 9-27 months). These were acetabular revisons involving major bone loss, with 62 stage III and 26 stage IV cases on the SOFCOT classification. Eighty-seven patients (87.5%) underwent structural bone allografting. RESULTS: The mean Merle d'Aubigné score increased from 9.6 ± 3.06 (range, 2-16) preoperatively to 15.5 ± 2.32 (range, 7-18) at the follow-up. Ten dislocations (10.4%) occurred, five of which were delayed over three months after the index procedure (5.2%), but there were no intraprosthetic dislocations. At the follow-up, the X-rays showed eight hardware failures, including one cross-plate fracture, one hook fracture, and one flange fracture. Analysis of the radiological position of the cup showed a mean lowering of 15.6mm and a 9.4mm lateralization compared to the preoperative position. One revision for aseptic loosening and another for septic loosening were performed. Taking all-cause acetabular component exchange as a criterion, the survival rate at 8 years was 95.6% (95% CI, 93.3-97.7%) and 99.3% (95% CI, 98.9-99.6%) if the endpoint was aseptic acetabular exchange. DISCUSSION: This study confirms the advantage of dual mobility cups during acetabular reconstruction cemented in antiprotrusio cages as a way to limit, without eliminating, the risk of dislocation. Therefore cemented fixation of dual mobility cups in cages appears to be a reliable short-term option.
Asunto(s)
Acetábulo/cirugía , Artroplastia de Reemplazo de Cadera , Cementos para Huesos , Articulación de la Cadera/cirugía , Inestabilidad de la Articulación/cirugía , Procedimientos de Cirugía Plástica/instrumentación , Reoperación/métodos , Adulto , Anciano , Anciano de 80 o más Años , Diseño de Equipo , Femenino , Estudios de Seguimiento , Articulación de la Cadera/fisiopatología , Humanos , Inestabilidad de la Articulación/etiología , Inestabilidad de la Articulación/fisiopatología , Masculino , Persona de Mediana Edad , Falla de Prótesis , Rango del Movimiento Articular , Estudios Retrospectivos , Factores de Tiempo , Resultado del TratamientoRESUMEN
BACKGROUND: Postoperative dislocation is the commonest complication following revision total hip arthroplasty (THA). HYPOTHESIS AND TYPE OF STUDY: Dual mobility cups are supposed to reduce the risk of THA instability. The present retrospective study tested this hypothesis on revision THAs and also, assessed this design contribution to acetabular fixation longevity. MATERIALS AND METHODS: The series was homogeneous and continuous, comprising a total of 163 revision THAs: 110 of them were bipolar revisions and 53 were restricted to the acetabular component exchange. Mean patient age was 68.7 years (range: 34-92 years). Novae (SERF, Décines) dual mobility cups were used in all cases: 110 cementless cups were used and 53 cups were cemented in a Kerboull reinforcement ring due to severe acetabular bone loss. RESULTS: Mean patients' follow-up (FU) was 60.4 + or - 17.6 months. There were six early dislocations (which were reduced without additional surgery and remained recurrence-free) and two cases of acetabular loosening. The total postoperative dislocation rate at the end of follow-up was 3.7% and the 7-year cup survivorship rate was 96.1% (95% CI: 92.8-99.2%). In revision for aseptic loosening, the instability rate was 2.9%; in the higher instability risk groups (i.e., revision for infection and or recurrent instability) the dislocation rate was respectively 9% and 0%. DISCUSSION: Dual mobility cups provided a dislocation rate of only 3.7% in revision THA, comparable to the one reported with standard implants for primary THA. This kind of cup design is especially suited to deal with high instability risk revision cases, where constrained components are generally recommended. It can also be indicated in cases of aseptic loosening, where it resulted in a 2.9% dislocation rate and only two impending failures of fixation. In terms of mechanical failure rate, these numbers compare well to the ones pertaining to tripolar and constrained implants. These later alternatives remain possible options but are not fully efficient in terms of long-term stability and fixation longevity. LEVEL OF STUDY: Level IV, retrospective or records-based.
Asunto(s)
Artroplastia de Reemplazo de Cadera , Luxación de la Cadera/prevención & control , Prótesis de Cadera , Diseño de Prótesis , Adulto , Anciano , Anciano de 80 o más Años , Análisis de Falla de Equipo , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Rango del Movimiento Articular , Recuperación de la Función , Estudios RetrospectivosRESUMEN
UNLABELLED: BACKGROUND OBJECTIVE: Femoral offset is supposed to influence the results of hip replacement but little is known about the accurate method of measure and the true effect of offset modifications. MATERIAL AND METHODS: This article is a collection of independent anatomic, radiological and clinical works, which purpose is to assess knowledge of the implications of femoral offset for preoperative templating and total hip arthroplasty. RESULTS: There is a strong correlation between femoral offset, abductors lever arm and hip abductor strength. Hip lateralization is independent of the femoral endomedullary characteristics. The abductors lever arm is highly correlated to the gluteus medius activation angle. There were correlations between femoral offset and endomedullary shape. The hip center was high and medial for stovepipe metaphysis while it was lower and lateralized for champagne - flute upper femur. A study was performed to compare the femoral offset measured by X-ray and CT-scan in 50 patients, demonstrated that plain radiography underestimates offset measurement. The 2D templating cannot appreciate the rotation of the lower limb. Taking into account the horizontal plane is essential to obtain proper 3D planning of the femoral offset. A randomized study was designed to compare femoral offset measurements after hip resurfacing and total hip arthroplasty. This study underlined hip resurfacing reduced the femoral offset, while hip replacement increased offset. However, the reduction of femoral offset after hip resurfacing does not affect the function. A pilot study was designed to assess the results of 120 hip arthroplasties with a modular femoral neck. This study showed that the use of a modular collar ensures an easier restoration of the femoral offset. A cohort of high offset stems (Lubinus 117 degrees) was retrospectively assessed. The survival rate was slightly lower that the standard design reported in the Swedish register. Finally, the measurement of offset and leg length was assessed with the help of computer assistance. The software changed the initial schedule (obtained by templating) in 29%. CONCLUSION: Therefore, femoral offset restoration is essential to improve function and longevity of hip arthroplasty. CT-scan is more accurate than plain radiography to assess femoral offset. Hip resurfacing decreases offset without effect on function. Modular neck and computer assistance may improve intraoperative calculation and reproduction of femoral offset. Increasing offset with a standard cemented design may decrease long-term fixation. Level IV: Retrospective or historical series.
Asunto(s)
Artroplastia de Reemplazo de Cadera/métodos , Cabeza Femoral/anatomía & histología , Cuello Femoral/anatomía & histología , Prótesis de Cadera , Cuidados Preoperatorios , Artroplastia de Reemplazo de Cadera/efectos adversos , Fenómenos Biomecánicos , Toma de Decisiones , Femenino , Fémur/anatomía & histología , Fémur/diagnóstico por imagen , Cabeza Femoral/diagnóstico por imagen , Cuello Femoral/diagnóstico por imagen , Articulación de la Cadera/anatomía & histología , Articulación de la Cadera/diagnóstico por imagen , Humanos , Masculino , Complicaciones Posoperatorias/prevención & control , Diseño de Prótesis , Falla de Prótesis , Radiografía , Rango del Movimiento Articular/fisiología , Sensibilidad y EspecificidadRESUMEN
INTRODUCTION: We report a continuous prospective series of patients operated on for total hip prosthesis femoral component loosening involving a bone defect. Reconstruction was performed using a hydroxyapatite-coated locked modular stem. The study's objective was to assess medium term clinical and X-ray results obtained with this original concept. MATERIALS AND METHODS: The patients included received a REEF (DePuy) femoral implant for aseptic loosening or loosening associated with a periprosthetic fracture. Implantation was systematically accompanied by an extended trochanteric osteotomy (ETO). Patients were followed up prospectively by clinical and X-ray examination. Their loosening was graded at inclusion according to Vives' classification as revised by SOFCOT in 1999. Analysis focused on actuarial implant survivorship, dislocation and the bone/implant interface. RESULTS: Forty-three hips were included: mean follow-up was 58.2 months (12-92) and mean age at surgery was 72.4 years (37-94). The main indications were severe bone loss rated grade III (n=15) or IV (n=16) according to the SOFCOT classification. There was one long-term failure, involving implant fracture secondary to nonunion of the femoral shaft. Mean Postel and Merle d'Aubigné (PMA) clinical assessment score increased from six preoperatively to 14.5 at end of follow-up. X-ray analysis found no stem migration by end of follow-up. There was consistent consolidation of the ETO around the stem, except in one case of stem fracture which evolved into tight nonunion. In terms of metaphyseal integration, five patients showed radiolucency without evolution over follow-up, and eight had severe calcar cortical atrophy at end of follow-up. Mean 5-year actuarial survivorship was 97.7+/-2.3%, with a 2% incidence of dislocation. DISCUSSION: The complications rate was low, and results were comparable with those reported in the literature. The study confirmed the interest of the extended trochanteric osteotomy exposure and the effectiveness of the hydroxyapatite-coated interlocked modular stem concept in the treatment of hip prosthesis loosening with femoral bone loss (involving or not the cortex). On analysis, the one case of failure does not prescribe the surgical technique employed. Implant osseointegration was difficult to analyze. The extent of the surgical approach and of its corresponding sequels, combined with the complexity of adjusting the implant, however, restrict this surgical option indications to level III and IV cases of femoral loosening.
Asunto(s)
Artroplastia de Reemplazo de Cadera/efectos adversos , Fémur/cirugía , Luxación de la Cadera/cirugía , Procedimientos de Cirugía Plástica/métodos , Falla de Prótesis , Adulto , Anciano , Anciano de 80 o más Años , Artroplastia de Reemplazo de Cadera/métodos , Materiales Biocompatibles Revestidos , Intervalos de Confianza , Durapatita/farmacología , Femenino , Estudios de Seguimiento , Luxación de la Cadera/diagnóstico por imagen , Luxación de la Cadera/etiología , Prótesis de Cadera , Humanos , Inestabilidad de la Articulación/diagnóstico por imagen , Inestabilidad de la Articulación/etiología , Inestabilidad de la Articulación/cirugía , Masculino , Persona de Mediana Edad , Dimensión del Dolor , Probabilidad , Estudios Prospectivos , Diseño de Prótesis , Rango del Movimiento Articular/fisiología , Recuperación de la Función , Reoperación , Medición de Riesgo , Factores de Tiempo , Tomografía Computarizada por Rayos X , Resultado del TratamientoRESUMEN
INTRODUCTION: Sagittal pelvic balance is a recognized factor influencing targeted acetabular-component anteversion during total hip arthroplasty implantation. However, no studies in the literature have systematically reported pelvic parameters data in the standing, sitting and supine positions. HYPOTHESIS: Variations in acetabular cup orientation can be traced to eventual pelvic balance changes in one of these three usual positions. MATERIALS AND METHODS: In these three positions (supine, standing and sitting), pelvic anatomical parameters and reference planes were radiologically defined from a group of 67 patients (average age: 70.2+/-3.2 years). The complete X-rays individual sets were digitized and measurements were obtained by a single operator using a Spineview software (previously, strictly validated for these kind of measurements). Positioning according to the Lewinnek pelvic coordinate system, which is considered as a possible source of errors when vertically standing or horizontally lying, was also investigated. RESULTS: The average pelvic incidence of 59.6 degrees did not vary in the sitting, supine or standing positions, with no statistically significant difference between sexes. The Legaye equation--pelvic incidence is equals to pelvic version plus sacral slope--was verified. Pelvic version increased by an average 22 degrees from the sitting to the supine or standing positions. Sacral slope varied in a reverse order. Pelvic-femoral angle (PFA) decreased by 20 degrees from the standing to the supine position. The Lewinnek plane was located 4 degrees posterior to the vertical plane. Whatever the position adopted, pelvi-Lewinnek angle appeared constant, averaging 12 degrees. DISCUSSION: The average pelvic incidence in this series was high, most probably associated with advancing patient age and/or pathology. The concept of functional anteversion appeared critical when taking into account pelvic version variations (according to the position, sitting, supine or standing) positions. The Lewinnek plane, commonly accepted as the reference plane for hip navigation, was individualised to each patient and should not be mistaken with the vertical plane; positioning of the femur in relation to the Lewinnek plane was also specific to each patient. Cumulative approximation on these two parameters at surgery resulted in a combined imprecision of 26 degrees when standing and 36 degrees when lying down. We have thus defined crucial parameters to be integrated in computer-assisted hip surgery softwares: positional variations of the pelvic version (functional anteversion), positioning of the Lewinnek plane, and PFA value (both specifically patient's dependant). If integration of these parameters into new sofwares versions appears possible, this would represent a reliable compromise between maximum prosthetic stability, maximum joint amplitudes and elimination of possible prosthetic conflict.
Asunto(s)
Articulación de la Cadera/anatomía & histología , Huesos Pélvicos/anatomía & histología , Equilibrio Postural , Anciano , Envejecimiento , Femenino , Articulación de la Cadera/diagnóstico por imagen , Humanos , Masculino , Huesos Pélvicos/diagnóstico por imagen , Radiografía , Rango del Movimiento Articular , Posición Supina , Cirugía Asistida por ComputadorAsunto(s)
Artroplastia de Reemplazo de Cadera , Articulación de la Cadera/fisiopatología , Rango del Movimiento Articular , Caminata , Adulto , Factores de Edad , Estudios de Seguimiento , Marcha , Articulación de la Cadera/diagnóstico por imagen , Humanos , Examen Físico , Radiografía , Análisis de Supervivencia , Factores de Tiempo , Resultado del TratamientoRESUMEN
PURPOSE OF THE STUDY: As part of the 2006 symposium of the French Hip and Knee Society devoted to the dual mobility socket, we report a retrospective multicentric series of 438 first-intention total hip prostheses with a dual mobility socket at a mean 17 years follow-up. The purpose of our report was to ascertain the 15-year survival of this socket and analyze failures. MATERIAL AND METHODS: The series included 438 primary replacements. This was a homogeneous multicentric series. The cementless sockets were 80 Novae-1 titanium Serf cups and 358 Novae-1 stainless steel Serf cups. All stems were inserted without cement: 185 Pf((R)) stainless steel screwed Serf stems, 228 PRO titanium screwed Serf stems, and 25 Corail stems. The mobile polyethylene insert was retaining. All of the heads were 22.2-mm chromium-cobalt heads. Degenerative hip disease was the main etiology and mean follow-up was 17 years (range, 12-20). Mean age at implantation was 54.8 years (range, 23-87). The actuarial method with a 95% confidence interval was used to determine the 15-year cup survival rate. RESULTS: At the last follow-up, none of the patients had presented an episode of early or late instability. Analysis of the socket at last follow-up showed 13 aseptic loosenings, 23 intraprosthetic dislocations, and seven replacements of the polyethylene insert for wear. The overall 15-year prosthesis survival rate was 89.2+/-8.7%. The overall 15-year socket survival rate was 96.3+/-3.7%. DISCUSSION: The fact that, at last follow-up, none of the implants had shown instability confirms the long-term stability of the dual mobility socket. The results in terms of 15-year survival confirm earlier reports. The main cause of failure was cup fixation, which is the weak point of this technique with the initial Novae cup design, which did not have hydroxyapatite coating. The second leading cause was intraprosthetic dislocation, which can be divided into three main categories. The first is intraprosthetic dislocation in a context of pure wear with normal function of the dual mobility socket; the retaining feature of the insert loses its efficacy due to wear. The second category is intraprosthetic dislocation in a context of cup loosening with a third-body effect and increased retention wear, in which case we consider that cup loosening is the primary event leading to rapid secondary wear and subsequent intraprosthetic dislocation. The third category is intraprosthetic dislocation caused by a blockage in a context of fibrosis or impingement involving severe heterotopic ossifications. We had only two femoral failures related to aseptic loosening, most certainly related to use of noncemented implants, which limits the extension of granulomas to the polyethylene. Studying the three series from Saint-Etienne more specifically, where three different configurations were used, it would appear that the titanium cup has a better survival rate and that the titanium used for the thinner necks may be an unfavorable factor for intraprosthetic dislocation.
Asunto(s)
Prótesis de Cadera , Adulto , Anciano , Anciano de 80 o más Años , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Diseño de Prótesis , Estudios Retrospectivos , Factores de Tiempo , Adulto JovenRESUMEN
PURPOSE OF THE STUDY: We studied a cementless anatomic stem combination with a cementless press-fit cup. The purpose of this work was to assess prospectively in a homogeneous consecutive series of patients, the clinical and radiological outcome of this prosthesis at five years follow-up. MATERIAL AND METHODS: The series included 176 hips with a total hip arthroplasty implanted between September 1997 and December 1998 by the same surgeon through an antero-lateral approach (Watson-Jones). We retained for study first intention implantations for primary or secondary joint degeneration. Fractures and revisions were excluded from the analysis. At last follow-up the survival was 93.2%. Patients were revised clinically (satisfaction Harris score). An independent surgeon unaware of the clinical results performed the radiological analysis (Engh and Ara score, Brooker classification). The Kaplan-Meier method was used for the survival curve expressed with 95% confidence interval and considering revision for all causes as failure. RESULTS: The five-year survival of the prosthesis was 98.8%. Clinically, the Harris score varied significantly (p<0.0001) from 32.9+/-1.2 preoperatively to 93.1+/-0.8 at last follow-up. Among the score items, pain exhibited the greatest improvement since at five years only, 10.2% of patients complained of mild pain. Thigh pain, often associated with cementless stems, was very low, 1.3%. Radiologically, the femoral implant was very stable with excellent bone remodelling as illustrated by the high Engh and Ara scores, 20.7+/-0.5 and 5+/-0.2 respectively. Polyethylene wear, 0.075mm/year, was below the usually observed levels. We noted a high rate of heterotopic ossifications, 65.1%, most Brooker I. DISCUSSION: The SPS stem has shown good results at five years, both clinically and radiographically. The objectives of a stable fixation over time and harmonious remodelling appear to be achieved. These promising results should be reexamined in a series with a longer follow-up.
Asunto(s)
Durapatita , Prótesis de Cadera , Adulto , Anciano , Anciano de 80 o más Años , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Estudios Prospectivos , Diseño de Prótesis , Factores de TiempoRESUMEN
We report two cases of ochronosis. This rare disease (1/1,000,000) transmitted by recessive autosomic inheritance results from an enzyme disorder. Clinically, the disease begins by black deposits in connective tissue followed by a group of symptoms, particularly involving the joints, and then destructive joint disease affecting the larger joints. Diagnosis is often established late. Early detection is important, preoperatively if possible, in order to avoid the serious complication of infectious endocarditis. These patients require adapted multidisciplinary care associating social support and symptomatic treatment. Drug therapy is currently under study and appears to provide effective symptom relief.