RESUMEN
Quinupristin-dalfopristin produced postantibiotic effects (PAEs) on exponentially growing (log phase) and nongrowing (lag phase) cultures of 0.4 to 6.9 h. PAEs of the other antibiotics tested were 0.5 to 1.9 h, determined with exponentially growing cultures. None of these antibiotics show a PAE on lag-phase bacteria.
Asunto(s)
Antibacterianos/farmacología , Staphylococcus aureus/efectos de los fármacos , Virginiamicina/análogos & derivados , Recuento de Colonia Microbiana , Resistencia a la Meticilina , Pruebas de Sensibilidad Microbiana , Virginiamicina/farmacologíaRESUMEN
A Peroxidase (EC 1.11.1.7) of the basidiomycet Phellinus igniarius was derived from mycel and a medium containing glucose and extract of yeast by using various methods of preparation. The enzyme resists extreme conditions (pH, temperature salt concentration). Its optimum pH for activities is in the acid range. Two isoenzymes were found. The molecular weight, isoelectric point, Michaelis-Menten constant, indolacetic acid oxidase activity and spectral and analytical properties of this peroxidase were determined. It is assumed that the enzyme has an intracellular as well as an extracellular field of activity.
Asunto(s)
Basidiomycota/enzimología , Peroxidasas/aislamiento & purificación , Polyporaceae/enzimología , Aminoácidos/análisis , Fenómenos Químicos , Química Física , Estabilidad de Medicamentos , Isoenzimas/análisis , Cinética , Peroxidasas/antagonistas & inhibidores , Análisis EspectralAsunto(s)
Moldes Quirúrgicos , Espondilolistesis/terapia , Espondilólisis/terapia , Factores de Edad , Niño , Preescolar , Femenino , Humanos , LactanteRESUMEN
This report describes the implantation of glass and glass-ceramics into soft tissues. These experiments revealed that our new glass and glass-ceramic materials are well compatible with soft tissues. The fibrous membrane surrounding such an implantat consists of normal dense collageneous connective tissue. The cells are fibroblasts and fibrocyt-like cells without any abnormal morphology. Macrophages could not be detected. However, the degree of implants solubility must be chosen with care, because high solubility of the implant increases the reaction of the surrounding soft tissues. The described materials are also compatible with osseous tissues. In our previous experiments we have already pointed out, that bonding developed between glass material and bone. Few weeks after implatation we have seen mature lamellar homegeneously mineralized bone opposed to the implant. There was no fibrous membrane between implant and bone. Longtime studies show that hitherto the described bonding exists about 2 years.