Asunto(s)
Síndrome de Inmunodeficiencia Adquirida/complicaciones , Antiinfecciosos/efectos adversos , Síndrome de Stevens-Johnson/etiología , Infecciones Oportunistas Relacionadas con el SIDA/tratamiento farmacológico , Infecciones Oportunistas Relacionadas con el SIDA/etiología , Adulto , Antiinfecciosos/uso terapéutico , Humanos , MasculinoRESUMEN
In January 1989, the Center for Sexually Transmitted Diseases (STD) of Galliera Hospital-Genoa was equipped with a network of 5 Personal Computers connected by a Token Ring to another Personal Computer which is the "server" unit. The Authors report their experiences in the use of the computer system and examine the advantages of networking in the management of a Center for Sexually Transmitted Disease.
Asunto(s)
Hospitales Especializados , Microcomputadores , Enfermedades de Transmisión Sexual , ItaliaRESUMEN
A case of a woman of 55-years-old with verrucous lesions localized on the dorsa of her feet and hands is reported. The light microecopy reveals marked hyperkeratosis with some degree of parakeratosis, epidermal atrophy and light lympho-histiocytic infiltrate in the papillary dermis. A diagnosis of hyperkeratosis lenticularis perstans is made on the basis of the physical examination and histologic findings. A brief review of the literature on the genetic, ultrastructural characteristics and pathogenesis of the disease is made.
Asunto(s)
Dermatosis del Pie/patología , Dermatosis de la Mano/patología , Queratosis/patología , Femenino , Humanos , Persona de Mediana EdadRESUMEN
Thirty-nine HIV-negative men, without apparent genital warts, were evaluated for evidence of subclinical genital condylomata by visual examination of the genitalia with colposcopy after the application of 5% acetic acid. 24 patients (group I) had a history of recurrent genital condylomata; 8 (group II) were sexual partners of women with HPV-related lesions and 7 (group III) presented another sexually transmitted disease. Under colposcopic magnification, acetowhite areas were biopsied for conventional histology and in situ hybridization using 6/11, 16/18 and 31/35/51 HPV-DNA probes. Colposcopy and histologic features were positive for condylomata acuminata in 16 patients of group III (14%). HPV 16/18 - whose oncogenic potentiality is well known - was detected in 3 patients: of these, one patient of group I presented a histologic picture suggestive of bowenoid papulosis.
Asunto(s)
Colposcopía , Condiloma Acuminado/diagnóstico , Neoplasias de los Genitales Masculinos/diagnóstico , Adolescente , Adulto , Condiloma Acuminado/patología , Sondas de ADN de HPV , Diagnóstico Diferencial , Neoplasias de los Genitales Masculinos/patología , Humanos , Masculino , Persona de Mediana EdadRESUMEN
A 52-year-old woman who had had ulcerative colitis for more than ten years experienced a third relapse of pyoderma gangrenosum of her lower extremities. She was treated with topical disodium cromoglycate. The dosage of salicylazosulfapyridine and steroids she was taking, and by which the ulcerative colitis, but not the pyoderma gangrenosum could be controlled, was not increased. Because pyoderma gangrenosum is often very difficult to treat and may require an aggressive approach using drugs that can cause serious side effects, we believe that a topical therapy is worth trying.
Asunto(s)
Cromolin Sódico/administración & dosificación , Úlcera de la Pierna/tratamiento farmacológico , Piodermia/tratamiento farmacológico , Administración Tópica , Colitis Ulcerosa/complicaciones , Cromolin Sódico/uso terapéutico , Femenino , Humanos , Úlcera de la Pierna/complicaciones , Persona de Mediana Edad , Piodermia/complicaciones , RecurrenciaRESUMEN
Recent studies reported in the literature have repeatedly pointed out the utility of imidazole derivatives, one of which is bifonazole, in the therapy of seborrheic dermatitis (SD). The cause of this pathological situation is still under discussion but the therapeutic success obtained with antimycotics speaks in favor of the pathogenetic importance of Malassezia ovale in this context. There is a high frequency of SD type complaints in patients with HIV infections in whom immune defenses against various pathogens, including yeasts, are deficient. We therefore verified the clinical efficacy of 1% bifonazole cream on 15 subjects with SD of the face, 9 of whom were affected with lymphadenopathy syndrome/AIDS-related complex (LAS/ARC). The treatment was administered over a four-week period and gave good results in 12 patients. The best results, however, were observed in those suffering from LAS/ARC.