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Objective: Compare the number of puerperal women submitted to blood transfusion before and after the implementation of a care protocol for postpartum hemorrhage (PPH) with multidisciplinary team training. Methods: Cross-sectional study in a university hospital, analyzing births from 2015 to 2019, compared the use of blood products before and after the adoption of a PPH protocol with multidisciplinary training. Results: Between 2015 and 2019, there were 17,731 births, with 299 (1.7%) postpartum women receiving blood products and 278 postpartum women were considered for this analysis, 128 (0.7%) at Time 1 and 150 (0.8%) at Time 2. After the multiprofessional team training (T2), there was a difference in the complete use of the PPH protocol (use of oxytocin, misoprostol and tranexamic acid) (T1 = 5.1% x T2 = 49.5%, p≤0.0001). An individual categorized analysis revealed that, in the T2 period, there was lower use of blood component units per patient compared to T1 (Mann-Whitney, p=0.006). It should be noted that at T1 and T2, 54% and 24% respectively received two units of blood products. It is important to highlight that after the multidisciplinary team training for the PPH protocol, the goal of zero maternal death due to hemorrhage was reached. Conclusion: The adoption of a specific protocol for PPH, combined with the training of a multidisciplinary team, had an impact on the ability to identify women at high risk of hemorrhage, resulting in a decrease in the use of blood components.

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Nowadays, layered double hydroxides (LDH), sometimes referred as hydrotalcite-like compounds, have gained great attention since their composition and structure can be easily modified, so that they can be implemented in multiple fields. LDH-based composite materials based on LDH exhibit tremendously improved properties such as high specific surface area, which promotes the accessibility to a greater number of LDH active sites, considerably improving their catalytic, adsorbent and biological activities. Therefore, this review summarizes and discusses the synthesis methods of composites constituted by LDH with other inorganic compounds such as zeolites, cationic clays, hydroxyapatites, among many others, and describe the resulting characteristics of the resulting composites, emphasizing the morphology. Brief descriptions of their properties and applications are also included.

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OBJECTIVE: The objective of this study was to assess the existence of the obesity paradox in patients with COVID-19 admitted to the intensive care unit. METHODS: This was a multicentric retrospective cohort study including individuals aged 18 years or older admitted to the intensive care unit with SARS-CoV-2. Data were obtained from electronic medical records. The primary outcome was in-hospital mortality. Multiple logistic regression and restricted cubic splines analyses were conducted to assess the association between BMI and mortality. RESULTS: From March 2020 to December 2021, 977 patients met the inclusion criteria, and 868 were included in the analysis. Obesity was identified in 382 patients (44%). Patients with obesity more often underwent prone positioning (42% vs. 28%; p < 0.001), although they used less vasoactive medications (57% vs. 68%; p < 0.001). The overall in-hospital mortality was 48%, with 44% observed in the subgroup of individuals with obesity and 50% in those without obesity (p = 0.06). Patients with BMI < 25 kg/m2 had the highest mortality. CONCLUSIONS: Obesity was not associated with higher mortality rates in critically ill patients with COVID-19. Moreover, patients with BMI < 25 kg/m2 had a higher mortality rate compared with those in higher BMI categories.

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BACKGROUND: COVID-19 is a disease known for its neurological involvement. SARS-CoV-2 infection triggers neuroinflammation, which could significantly contribute to the development of long-term neurological symptoms and structural alterations in the gray matter. However, the existence of a consistent pattern of cerebral atrophy remains uncertain. OBJECTIVE: Our study aimed to identify patterns of brain involvement in recovered COVID-19 patients and explore potential relationships with clinical variables during hospitalization. METHODOLOGY: In this study, we included 39 recovered patients and 39 controls from a pre-pandemic database to ensure their non-exposure to the virus. We obtained clinical data of the patients during hospitalization, and 3 months later; in addition we obtained T1-weighted magnetic resonance images and performed standard screening cognitive tests. RESULTS: We identified two groups of recovered patients based on a cluster analysis of the significant cortical thickness differences between patients and controls. Group 1 displayed significant cortical thickness differences in specific cerebral regions, while Group 2 exhibited significant differences in the cerebellum, though neither group showed cognitive deterioration at the group level. Notably, Group 1 showed a tendency of higher D-dimer values during hospitalization compared to Group 2, prior to p-value correction. CONCLUSION: This data-driven division into two groups based on the brain structural differences, and the possible link to D-dimer values may provide insights into the underlying mechanisms of SARS-COV-2 neurological disruption and its impact on the brain during and after recovery from the disease.

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Abstract Objective Compare the number of puerperal women submitted to blood transfusion before and after the implementation of a care protocol for postpartum hemorrhage (PPH) with multidisciplinary team training. Methods Cross-sectional study in a university hospital, analyzing births from 2015 to 2019, compared the use of blood products before and after the adoption of a PPH protocol with multidisciplinary training. Results Between 2015 and 2019, there were 17,731 births, with 299 (1.7%) postpartum women receiving blood products and 278 postpartum women were considered for this analysis, 128 (0.7%) at Time 1 and 150 (0.8%) at Time 2. After the multiprofessional team training (T2), there was a difference in the complete use of the PPH protocol (use of oxytocin, misoprostol and tranexamic acid) (T1 = 5.1% x T2 = 49.5%, p≤0.0001). An individual categorized analysis revealed that, in the T2 period, there was lower use of blood component units per patient compared to T1 (Mann-Whitney, p=0.006). It should be noted that at T1 and T2, 54% and 24% respectively received two units of blood products. It is important to highlight that after the multidisciplinary team training for the PPH protocol, the goal of zero maternal death due to hemorrhage was reached. Conclusion The adoption of a specific protocol for PPH, combined with the training of a multidisciplinary team, had an impact on the ability to identify women at high risk of hemorrhage, resulting in a decrease in the use of blood components.

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Introducción. Las actividades profesionales confiables (APROC) son 13 actividades que los médicos recién graduados deberían poder realizar sin supervisión directa. Nuestro objetivo fue evaluar la percepción de residentes y docentes acerca de la autonomía para realizar las APROC, luego de 2 años del inicio de la pandemia. Materiales y métodos. Estudio de corte transversal, que incluyó residentes de primer año de especialidades clínicas y quirúrgicas, y sus docentes. Se enviaron cuestionarios electrónicos y anónimos. Resultados. Se incluyeron 31 residentes y 20 docentes. La mayoría de los residentes creía que podía realizar en forma autónoma 8 de las 13 APROC. Para la mayoría de los docentes, los residentes requerían supervisión directa para 11 de las 13 actividades. Se observaron diferencias significativas entre la percepción de residentes y docentes en 8 de las 13 APROC. Conclusión. La percepción de autonomía para realizar las APROC al inicio de la residencia fue considerablemente mayor en residentes que en sus docentes.

Introduction. The entrustable professional activities (EPAs) are 13 activities that new medical graduates should be able to perform without direct supervision. Our objective was to assess the perceptions of residents and teachers regarding their autonomy to perform the EPAs 2 years after the onset of the COVID-19 pandemic. Materials and methods. Cross-sectional study of first-year residents of clinical and surgical specialties and their teachers. Electronic, anonymous questionnaires were used. Results. Subjects were 31 residents and 20 teachers. Most residents believed that they were able to perform 8 of the 13 EPAs independently. According to most teachers, residents required direct supervision to perform 11 of the 13 EPAs. Significant differences were observed between residents' and teachers' perceptions in 8 of the 13 EPAs. Conclusion. The perception of autonomy to perform the EPAs in the beginning of the residency program was considerably better among residents than their teachers.

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Introduction. The entrustable professional activities (EPAs) are 13 activities that new medical graduates should be able to perform without direct supervision. Our objective was to assess the perceptions of residents and teachers regarding their autonomy to perform the EPAs 2 years after the onset of the COVID-19 pandemic. Materials and methods. Cross-sectional study of first-year residents of clinical and surgical specialties and their teachers. Electronic, anonymous questionnaires were used. Results. Subjects were 31 residents and 20 teachers. Most residents believed that they were able to perform 8 of the 13 EPAs independently. According to most teachers, residents required direct supervision to perform 11 of the 13 EPAs. Significant differences were observed between residents' and teachers' perceptions in 8 of the 13 EPAs. Conclusion. The perception of autonomy to perform the EPAs in the beginning of the residency program was considerably better among residents than their teachers.

Introducción. Las actividades profesionales confiables (APROC) son 13 actividades que los médicos recién graduados deberían poder realizar sin supervisión directa. Nuestro objetivo fue evaluar la percepción de residentes y docentes acerca de la autonomía para realizar las APROC, luego de 2 años del inicio de la pandemia. Materiales y métodos. Estudio de corte transversal, que incluyó residentes de primer año de especialidades clínicas y quirúrgicas, y sus docentes. Se enviaron cuestionarios electrónicos y anónimos. Resultados. Se incluyeron 31 residentes y 20 docentes. La mayoría de los residentes creía que podía realizar en forma autónoma 8 de las 13 APROC. Para la mayoría de los docentes, los residentes requerían supervisión directa para 11 de las 13 actividades. Se observaron diferencias significativas entre la percepción de residentes y docentes en 8 de las 13 APROC. Conclusión. La percepción de autonomía para realizar las APROC al inicio de la residencia fue considerablemente mayor en residentes que en sus docentes.

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BACKGROUND: Previous studies have demonstrated a beneficial effect of early use of corticosteroids in patients with COVID-19. This study aimed to compare hospitalized patients with COVID-19 who received short-course corticosteroid treatment with those who received prolonged-course corticosteroid treatment to determine whether prolonged use of corticosteroids improves clinical outcomes, including mortality. METHODS: This is a retrospective cohort study including adult patients with positive testing for Sars-CoV-2 hospitalized for more than 10 days. Data were obtained from electronic medical records. Patients were divided into two groups, according to the duration of treatment with corticosteroids: a short-course (10 days) and a prolonged-course (longer than 10 days) group. Inverse probability treatment weighting (IPTW) analysis was used to evaluate whether prolonged use of corticosteroids improved outcomes. The primary outcome was in-hospital mortality. Secondary outcomes were hospital infection and the association of different doses of corticosteroids with hospital mortality. Restricted cubic splines were used to assess the nonlinear association between mortality and dose and duration of corticosteroids use. RESULTS: We enrolled 1,539 patients with COVID-19. Among them, 1127 received corticosteroids for more than 10 days (prolonged-course group). The in-hospital mortality was higher in patients that received prolonged course corticosteroids (39.5% vs. 26%, p < 0.001). The IPTW revealed that prolonged use of corticosteroids significantly increased mortality [relative risk (RR) = 1.52, 95% confidence interval (95% CI): 1.24-1.89]. In comparison to short course treatment, the cubic spline analysis showed an inverted U-shaped curve for mortality, with the highest risk associated with the prolonged use at 30 days (RR = 1.50, 95% CI 1.21-1.78). CONCLUSIONS: Prolonged course of treatment with corticosteroids in hospitalized patients with COVID-19 was associated with higher mortality.

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INTRODUCTION: The COVID-19 pandemic forced residency programs to adapt their selection processes. Our objective was to describe the experience of virtual interviews conducted to select residents through applicants' perception. POPULATION AND METHODS: An electronic questionnaire was sent to health care residency applicants after their interviews conducted in 2020. RESULTS: Two-hundred and twenty-one questionnaires were collected and the average distance to the facility was 163 km. Also, 67.9% of the applicants used a personal computer, 98.2% felt that they were treated appropriately, 77.8% were able to state their ideas, and 12.2% reported technical difficulties. In addition, 32.6% said that they would prefer virtual interviews for future selection processes and 17.6%, that it would be irrelevant. CONCLUSIONS: Virtual interviews allowed the resident selection process to be completed; one third of applicants would prefer virtual interviews in the future and there were no apparent technological limitations.

Introducción. La pandemia por COVID-19 obligó a los sistemas de residencias a adaptar sus procesos de selección. Nuestro objetivo fue describir la experiencia de virtualización de las entrevistas de selección de residentes a través de la percepción de las personas aspirantes. Población y métodos. Se envió un cuestionario electrónico a las personas aspirantes de residencias para profesionales de la salud luego de las entrevistas en 2020. Resultados. Se obtuvieron 221 respuestas y la distancia promedio a la institución fue 163 km. El 67,9 % de los aspirantes utilizaron computadora personal; el 98,2 % percibió un trato apropiado; el 77,8 % pudo expresar sus ideas, y el 12,2 % manifestó dificultades técnicas. El 32,6 % refirió que, para próximos procesos de selección, preferiría entrevistas virtuales y al 17,6 % le sería indistinto. Conclusiones. Las entrevistas virtuales permitieron completar el proceso de selección de residentes; un tercio preferiría entrevistas virtuales en el futuro y no hubo limitaciones tecnológicas evidentes.

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Introducción. La pandemia por COVID-19 obligó a los sistemas de residencias a adaptar sus procesos de selección. Nuestro objetivo fue describir la experiencia de virtualización de las entrevistas de selección de residentes a través de la percepción de las personas aspirantes. Población y métodos. Se envió un cuestionario electrónico a las personas aspirantes de residencias para profesionales de la salud luego de las entrevistas en 2020. Resultados. Se obtuvieron 221 respuestas y la distancia promedio a la institución fue 163 km. El 67,9 % de los aspirantes utilizaron computadora personal; el 98,2 % percibió un trato apropiado; el 77,8 % pudo expresar sus ideas, y el 12,2 % manifestó dificultades técnicas. El 32,6 % refirió que, para próximos procesos de selección, preferiría entrevistas virtuales y al 17,6 % le sería indistinto. Conclusiones. Las entrevistas virtuales permitieron completar el proceso de selección de residentes; un tercio preferiría entrevistas virtuales en el futuro y no hubo limitaciones tecnológicas evidentes.

Introduction. The COVID-19 pandemic forced residency programs to adapt their selection processes. Our objective was to describe the experience of virtual interviews conducted to select residents through applicants' perception. Population and methods. An electronic questionnaire was sent to health care residency applicants after their interviews conducted in 2020. Results. Two-hundred and twenty-one questionnaires were collected and the average distance to the facility was 163 km. Also, 67.9% of the applicants used a personal computer, 98.2% felt that they were treated appropriately, 77.8% were able to state their ideas, and 12.2% reported technical difficulties. In addition, 32.6% said that they would prefer virtual interviews for future selection processes and 17.6%, that it would be irrelevant. Conclusions. Virtual interviews allowed the resident selection process to be completed; one third of applicants would prefer virtual interviews in the future and there were no apparent technological limitations.

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Introducción. La expresión del género y laidentidad sexual no siempre coinciden con el sexo asignado al nacer. Nos propusimos como objetivo explorar las percepciones de género en adolescentes que consultaron en un hospital universitario de la comunidad. Población y métodos. Se diseñó un estudio de corte transversal. Se realizó una encuesta anónima en la sala de espera a los pacientes de 13 a 20 años que se atendieron en los consultorios externos de adolescencia entre abril y diciembre del 2019. Resultados. Respondieron la encuesta 834 adolescentes y el promedio de edad de los encuestados fue de 16,3 ± 2,3 años. El 3,3 % de los adolescentes (2,9 % mujeres y 4,3 % varones) se percibieron con una identidad de género diferente a su sexo de nacimiento. El 26 % no percibió su orientación sexual en términos heteronormativos, casi el 10 % se sintió discriminado por su orientación sexual, y esto estuvo asociado a la orientación sexual no heteronormativa (p <0,0001). Las adolescentes mujeres besaron en la boca a personas del mismo sexo en mayor medida que los varones, 44,8 % versus 19 % (p <0,0001). Conclusiones. El 3,3 % de la población adolescente se percibió con una identidad de género diferente al sexo de nacimiento y el 26 % tuvo una orientación sexual no heteronormativa.

Introduction. Gender expression and sexual identity are not always the same as the sex assigned at birth. Our objective was to explore gender perceptions among adolescents who attended a teaching hospital in the Autonomous City of Buenos Aires. Population and methods. This was a cross- sectional study. An anonymous survey was administered to patients aged 13-20 years at the waiting room of the outpatient adolescent clinic between April and December 2019. Results. A total of 834 adolescents completed the survey; their average age was 16.3 ± 2.3 years. Among them, 3.3% (2.9% females and 4.3% males) perceived their gender identity as different from their sex assigned at birth; 26% perceived their sexual orientation was not heteronormative; almost 10% experienced discrimination due to their sexual orientation; and this was associated with a non-heteronormative sexual orientation (p < 0.0001). Female adolescents kissed same sex persons on the mouth more often than male adolescents: 44.8% versus 19% (p < 0.0001). Conclusions. In this population of adolescents, 3.3% perceived their gender identity was different from their sex assigned at birth and 26% had a non-heteronormative sexual orientation.

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INTRODUCTION: Gender expression and sexual identity are not always the same as the sex assigned at birth. Our objective was to explore gender perceptions among adolescents who attended a teaching hospital in the Autonomous City of Buenos Aires. MATERIAL AND METHODS: This was a cross-sectional study. An anonymous survey was administered to patients aged 13-20 years at the waiting room of the outpatient adolescent clinic between April and December 2019. RESULTS: A total of 834adolescents completed the survey; their average age was 16.3 ± 2.3 years. Among them, 3.3% (2.9% females and 4.3% males) perceived their gender identity as different from their sex assigned at birth; 26% perceived their sexual orientation was not heteronormative; almost 10% experienced discrimination due to their sexual orientation; and this was associated with a non-heteronormative sexual orientation (p < 0.0001). Female adolescents kissed same sex persons on the mouth more often than male adolescents: 44.8% versus 19% (p < 0.0001). CONCLUSIONS: In this population of adolescents, 3.3% perceived their gender identity was different from their sex assigned at birth and 26% had a non-heteronormative sexual orientation.

Introducción. La expresión del género y la identidad sexual no siempre coinciden con el sexo asignado al nacer. Nos propusimos como objetivo explorar las percepciones de género en adolescentes que consultaron en un hospital universitario de la comunidad. Población y métodos. Se diseñó un estudio de corte transversal. Se realizó una encuesta anónima en la sala de espera a los pacientes de 13 a 20 años que se atendieron en los consultorios externos de adolescencia entre abril y diciembre del 2019. Resultados. Respondieron la encuesta 834 adolescentes y el promedio de edad de los encuestados fue de 16,3 ± 2,3 años. El 3,3 % de los adolescentes (2,9 % mujeres y 4,3 % varones) se percibieron con una identidad de género diferente a su sexo de nacimiento. El 26 % no percibió su orientación sexual en términos heteronormativos, casi el 10 % se sintió discriminado por su orientación sexual, y esto estuvo asociado a la orientación sexual no heteronormativa (p< 0,0001). Las adolescentes mujeres besaron en la boca a personas del mismo sexo en mayor medida que los varones, 44,8 % versus 19 % (p<0,0001). Conclusiones. El 3,3 % de la población adolescente se percibió con una identidad de género diferente al sexo de nacimiento y el 26 % tuvo una orientación sexual no heteronormativa.

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The cerebellar cognitive affective syndrome (CCAS) has been consistently described in patients with acute/subacute cerebellar injuries. However, studies with chronic patients have had controversial findings that have not been explored with new cerebellar-target tests, such as the CCAS scale (CCAS-S). The objective of this research is to prove and contrast the usefulness of the CCAS-S and the Montreal Cognitive Assessment (MoCA) test to evaluate cognitive/affective impairments in patients with chronic acquired cerebellar lesions, and to map the cerebellar areas whose lesions correlated with dysfunctions in these tests. CCAS-S and MoCA were administrated to 22 patients with isolated chronic cerebellar strokes and a matched comparison group. The neural bases underpinning both tests were explored with multivariate lesion-symptom mapping (LSM) methods. MoCA and CCAS-S had an adequate test performance with efficient discrimination between patients and healthy volunteers. However, only impairments determined by the CCAS-S resulted in significant regional localization within the cerebellum. Specifically, patients with chronic cerebellar lesions in right-lateralized posterolateral regions manifested cognitive impairments inherent to CCAS. These findings concurred with the anterior-sensorimotor/posterior-cognitive dichotomy in the human cerebellum and revealed clinically intra- and cross-lobular significant regions (portions of right lobule VI, VII, Crus I-II) for verbal tasks that overlap with the "language" functional boundaries in the cerebellum. Our findings prove the usefulness of MoCA and CCAS-S to reveal cognitive impairments in patients with chronic acquired cerebellar lesions. This study extends the understanding of long-term CCAS and introduces multivariate LSM methods to identify clinically intra- and cross-lobular significant regions underpinning chronic CCAS.

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Introduction: The COVID-19 pandemic limited in person presentation of final works and theses for the completion of specializations, masters and doctorates. Objective: To describe the experience in remote presentations of summative essays and thesis. Materials and methods: A qualitative-quantitative cross-sectional study was carried out. Perceptions of graduates and examiner board members were explored through a questionnaire. Results: 54 presentations were included: 53.7% specializations, 40.7% masters and 5.6% doctorates. The average audience number was 34 and distance to the university was 273.6 km. 116 professionals answered: graduates 28.4% and examiner board members 71.6%. They were female gender in 51.5% and 36.1%, respectively. 100% of graduates and 96.3% of examiner board members believed that they were able to present the results of the investigation, and only 3% and 7.3%, respectively, reported technical difficulties. Positive aspects identified by graduates were higher comfort (45.5%), and greater audience number (36.4%); while the examiner board members identified preventing transportation (37,8%) and taking advantage of technologies (35,4%). Graduates identified as negative aspects audience invisibility (33.3%), and potential threat of technical difficulties (27.3%); whilst the examiner board members identified none (31,7%), and potential threat of technical difficulties (20,7%). Conclusion: Remote presentations were successful for graduates and examiner board members, and allowed to continue and finish academic postgraduate training.

Introducción: La pandemia por COVID-19 limitó la presentación de trabajos finales y tesis para la finalización de especializaciones, maestrías y doctorado en forma presencial. Objetivo: Describir la experiencia en presentaciones a distancia de trabajos finales integradores y tesis. Materiales y métodos: Estudio cuali-cuantitativo de corte transversal. Se exploraron las percepciones de los graduados y jurados mediante un cuestionario. Resultados: Se incluyeron 54 presentaciones: 53,7% especializaciones, 40,7% maestrías y 5,6% doctorados. El promedio de audiencia fue de 34 personas y la distancia a la universidad fue 273,6 km. Respondieron 116 profesionales: graduados 28,4% y jurados 71,6%. Entre ellos 51,5% y 36,1% eran de género femenino, respectivamente. El 100% de los graduados y el 96,3% de los jurados opinaron que pudieron exponer los resultados de la investigación y solo el 3% y 7,3% respectivamente expresó que existieron dificultades técnicas. Los aspectos positivos identificados por los graduados fueron mayor comodidad (45,5%) y mayor número de audiencia (36,4%); mientras que los jurados identificaron evitar traslados (37,8%) y aprovechamiento de tecnologías (35,4%). Los graduados identificaron como aspectos negativos la invisibilidad de la audiencia (33,3%) y potenciales dificultades técnicas (27,3%); mientras que los jurados no identificaron ninguno (31,7%) y potenciales de dificultades técnicas (20,7%). Conclusión: La modalidad de presentaciones a distancia fue satisfactoria tanto para los graduados como para los jurados y permitió dar continuidad y completar el proceso educativo de las carreras de posgrado.

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OBJECTIVE: Examine the relationship between Premenstrual Syndrome (PMS) and sleep in different menstrual cycle phases. METHODS: Case-control survey conducted at the Primary Care Service and Clinical Research Center at Hospital de Clínicas de Porto Alegre with women aged between 18 and 45 years old. Women filled the Brazilian version of the Premenstrual Symptoms Screen Tool (PSST) for the screening of PMS; participants with positive screening completed the Daily Record of Severity of Problems (DRSP) to confirm PMS diagnosis. We applied the Pittsburg Sleep Quality Index (PSQI) and Epworth Sleepiness Scale (ESS) Brazilian versions in the luteal phase (LP) and follicular phase (FP). RESULTS AND CONCLUSION: 69 women were characterized with PMS and 52 without PMS. The risk of poor sleep quality (SQ) was two times higher in women with PMS (p = .006; OR = 3.057; IC95% 1.44-6.45). An interaction between no PMS and LP was found in ESS (p = .014; generalized estimating equation - GEE - adjusted for multiple comparisons by the Bonferroni test and adjusted by age); besides that, women with PMS had greater scores in ESS (p = .022; GEE adjusted by age).

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La incidencia del paro cardíaco pediátrico es desconocida; sus principales etiologías son cardiopatías congénitas, miocardiopatías y arritmias ventriculares. El electrocardiograma es un método diagnóstico que podría detectarlas precozmente y disminuir la morbimortalidad. El objetivo del estudio fue describir las habilidades de residentes de Pediatría para reconocer si un electrocardiograma era normal o anormal y realizar un diagnóstico electrocardiográfico preciso, antes y después de una intervención educativa. Participaron médicos residentes de primer año de Pediatría. Se tomó una evaluación con 12 trazados de electrocardiogramas, antes y después de un módulo educativo, y se compararon los puntajes mediante la prueba de "t" para datos pareados. No se halló diferencia entre ambas evaluaciones para la interpretación de electrocardiogramas como normales o anormales (p: 0,42). Sin embargo, hubo una diferencia estadísticamente significativa en cuanto a los diagnósticos de certeza (p < 0,002). Los diagnósticos de certeza electrocardiográficos mejoraron luego de implementar un módulo educacional

The incidence of pediatric cardiac arrest is unknown; its main etiologies are congenital heart diseases, cardiomyopathies, and ventricular arrhythmias. An electrocardiogram (ECG) is a diagnostic method that may allow to detect them in an early manner and reduce morbidity and mortality.The objective of this study was to describe pediatric residents' skills to determine if an ECG was normal or abnormal and make an accurate electrocardiographic diagnosis before and after an educational intervention. First-year pediatric residents participated in this study. An assessment including 12 ECG tracings was done before and after an educational module, and scores were compared using the t-test for paired data. No differences were observed between both assessments regarding the interpretation of ECG as normal or abnormal (p: 0.42). However, a statistically significant difference was observed in definitive diagnoses (p < 0.002). Definitive electrocardiographic diagnoses improved after the implementation of an educational module.

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The incidence of pediatric cardiac arrest is unknown; its main etiologies are congenital heart diseases, cardiomyopathies, and ventricular arrhythmias. An electrocardiogram (ECG) is a diagnostic method that may allow to detect them in an early manner and reduce morbidity and mortality. The objective of this study was to describe pediatric residents' skills to determine if an ECG was normal or abnormal and make an accurate electrocardiographic diagnosis before and after an educational intervention. First-year pediatric residents participated in this study. An assessment including 12 ECG tracings was done before and after an educational module, and scores were compared using the t-test for paired data. No differences were observed between both assessments regarding the interpretation of ECG as normal or abnormal (p: 0.42). However, a statistically significant difference was observed in definitive diagnoses (p < 0.002). Definitive electrocardiographic diagnoses improved after the implementation of an educational module.

La incidencia del paro cardíaco pediátrico es desconocida; sus principales etiologías son cardiopatías congénitas, miocardiopatías y arritmias ventriculares. El electrocardiograma es un método diagnóstico que podría detectarlas precozmente y disminuir la morbimortalidad. El objetivo del estudio fue describir las habilidades de residentes de Pediatría para reconocer si un electrocardiograma era normal o anormal y realizar un diagnóstico electrocardiográfico preciso, antes y después de una intervención educativa. Participaron médicos residentes de primer año de Pediatría. Se tomó una evaluación con 12 trazados de electrocardiogramas, antes y después de un módulo educativo, y se compararon los puntajes mediante la prueba de "t" para datos pareados. No se halló diferencia entre ambas evaluaciones para la interpretación de electrocardiogramas como normales o anormales (p: 0,42). Sin embargo, hubo una diferencia estadísticamente significativa en cuanto a los diagnósticos de certeza (p<0,002). Los diagnósticos de certeza electrocardiográficos mejoraron luego de implementar un módulo educacional.

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BACKGROUND: Spinocerebellar ataxia type 10 is a neurodegenerative disorder caused by the expansion of an ATTCT pentanucleotide repeat. Its clinical features include ataxia and, in some cases, epileptic seizures. There is, however, a dearth of information about its cognitive deficits and the neural bases underpinning them. OBJECTIVES: The objectives of this study were to characterize the performance of spinocerebellar ataxia type 10 patients in 2 cognitive domains typically affected in spinocerebellar ataxias, memory and executive function, and to correlate the identified cognitive impairments with ataxia severity and cerebral/cerebellar cortical thickness, as quantified by MRI. METHODS: Memory and executive function tests were administered to 17 genetically confirmed Mexican spinocerebellar ataxia type 10 patients, and their results were compared with 17 healthy matched volunteers. MRI was performed in 16 patients. RESULTS: Patients showed deficits in visual and visuospatial short-term memory, reduced storage capacity for verbal memory, and impaired monitoring, planning, and cognitive flexibility, which were ataxia independent. Patients with seizures (n = 9) and without seizures (n = 8) did not differ significantly in cognitive performance. There were significant correlations between short-term visuospatial memory impairment and posterior cerebellar lobe cortical thickness (bilateral lobule VI, IX, and right X). Cognitive flexibility deficiencies correlated with cerebral cortical thickness in the left middle frontal, cingulate, opercular, and temporal gyri. Cerebellar cortical thickness in several bilateral regions was correlated with motor impairment. CONCLUSIONS: Patients with spinocerebellar ataxia type 10 show significant memory and executive dysfunction that can be correlated with deterioration in the posterior lobe of the cerebellum and prefrontal, cingulate, and middle temporal cortices. © 2021 International Parkinson and Movement Disorder Society.

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