RESUMEN
OBJECTIVE: The aim: Was the comparative hygienic evaluation of the pesticide behavior in the soil after application on cereals. PATIENTS AND METHODS: Material and methods: Methods of full-scale in-field hygienic experiment, high-performance liquid (HPLC), gas-liquid (GLC), thin-layer chromatography, statistical, bibliography were used in the research. RESULTS: Results: Data on the detailed conditions and land parcels treated with studied pesticide formulation and its a.i. are highlighted in the article. The actual levels of the different classes a.i. content in soil and its dynamics were determined, based on which the dissipation rate constants (K) were calculated, as well as quantitative parameters of stability (τ50, τ95, τ99). CONCLUSION: Conclusions: Azoxystrobin, benzovindiflupyr, epoxiconazole, propiconazole, prochloraz, cyproconazole can be classified as of low hazardous substances, and trinexapac-ethyl, kresoxim-methyl, picoxystrobin, and tebuconazole are considered to be moderately hazardous. Among all pesticides studied, tebuconazole is the longest persists in the soil; epoxiconazole and propiconazole are most likely to disappear from the soil. Calculated values of half-lives of the studied substances in the agro-climatic conditions of Ukraine are slightly different from the results of in-field experiments that were conducted in other countries, namely: azoxystrobin, epoxiconazole, propiconazole, and cyproconazole disappear from the soil more quickly; the kresoxim-methyl and pinoxaden disappear more slowly. Meanwhile, the persistence of benzovindiflupyr, picoxystrobin, prochloraz, trinexapac-ethyl, and tebuconazole does not differ from the persistence in soils of European countries.
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Plaguicidas , Agricultura , Grano Comestible/química , Europa (Continente) , Suelo , UcraniaRESUMEN
OBJECTIVE: The aim: To determine the pathogenetic expediency, efficiency and the place of therapeutic plasmapheresis in a complex treatment of patients with chronic hepatitis. PATIENTS AND METHODS: Materials and methods: It was carried out the analysis of case histories of 77 patients. In the course of treatment, the patients were diagnosed with chronic toxic hepatitis (K.71). Diagnosis was exposed in accordance with the official documentation introduced by the Gastroenterological department of Sumy Regional Clinical Hospital CH"SRCH", Sumy Regional Infectious Diseases Clinical Hospital named after Krasovytsky ZY and Sumy Regional Center of Blood Service. RESULTS: Results: It was found that total protein indicator is the normal range and albumin after plasmapheresis and during conservative treatment. Markers of cytolysis and cholestasis are have great value may. The most significant changes were observed in rates indicating lesion of the hepatic parenchyma, including ALT, AsAT and alkaline phosphatase. In conservative treatment, the percentageof the alkaline phosphatase level improved by 31%, after the course of plasmapheresis - by 58%. The obtained figures of cholestasis indexes indicate the effectiveness of both methods of treatment, but treatment with plasmapheresis has a more expressed effect on the decrease of alkaline phosphatase level. The level of bilirubin improve on 38,8% after plasmapheresis and 65% in the comparison group. CONCLUSION: Conclusion: Inclusion in the complex therapy of chronic hepatitis plasmapheresis reduces the severity of cytolysis and cholestasis, increases remission and significantly improves clinical manifestations.
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Hepatitis Crónica , Bilirrubina , Colestasis , Humanos , PlasmaféresisRESUMEN
OBJECTIVE: Introduction: The current negative trends in the health of students' youth, which according to many researchers is a social group with an increased risk of diseases, indicate the need to address the problem of preserving and strengthening the health of students through the introduction of effective approaches to the prevention of diseases, risk factors for their development and the formation of the principles of a healthy lifestyle. The aim: Substantiation of measures aimed at prevention of non-communicable diseases and risk factors for their development in students by studying their health and lifestyle, evaluation of international experience in this field. PATIENTS AND METHODS: Materials and methods: We have analyzed the sources of domestic and foreign research literature and conducted sociological research among 332 students of higher education institutions: linguistic, medical and technical universities. It had been used bibliosemantic, sociological and medical-statistical methods. CONCLUSION: Conclusions: Under conditions of the current intensification of the educational process in higher education universities, which is accompanied by a tense education regime, increase of educational load and negative impact on the health of students, the importance of solving the problem of preserving and strengthening the health of student youth is increased. Therefore priority attention is needed the complex realization of measures to the effective prevention of diseases and risk factors for their development among students, creation of pre-conditions for forming in students the principles of healthy way of life and health-protecting behavior, improvement of medical care and implementation of monitoring the health status of students.