RESUMEN
Trace elements in organisms are normally higher in well-developed coastal areas than on oceanic islands. Few studies have used seaweeds as their sentinels on islands. This study established background levels of trace elements (As, Cd, Pb, Zn, Cu and Hg) for four seaweed species (Dictyopteris delicatula and Canistrocarpus cervicornis, brown algae; Ceratodictyon variabile and Palisada perforata, red algae) from Trindade, an oceanic Brazilian island, and verified potential differences associated to distinct environmental conditions. Spatial differences were not detected for As, Hg and Cd in samples, although the highest concentrations of these elements were observed in brown seaweeds. The highest Zn, Pb and Cu concentrations in seaweeds from the only inhabited beach may be a signal of the onset of human footprints on this still pristine, remote island. By comparison with background described in the literature, concentrations of trace elements in seaweeds were low, thus, allowing them to be considered reference levels.
Asunto(s)
Phaeophyceae/química , Rhodophyta/química , Algas Marinas/química , Oligoelementos/análisis , Contaminantes Químicos del Agua/análisis , Océano Atlántico , Brasil , Monitoreo del Ambiente , Humanos , Islas , Mercurio/análisisRESUMEN
Holter's test was performed in eight patients with advanced breast cancer and paraneoplastic hypercalcemia. In spite of several reports of cardiac arrhythmias, none were found in these patients.
Asunto(s)
Arritmias Cardíacas/etiología , Hipercalcemia/complicaciones , Adulto , Neoplasias de la Mama/complicaciones , Electrocardiografía Ambulatoria , Femenino , Humanos , Hipercalcemia/etiología , Hipercalcemia/fisiopatología , Persona de Mediana EdadRESUMEN
Hodgkin's lymphoma (HL) simulating acute cholestatic hepatitis is a very unusual clinical picture. Massive liver infiltration with conspicuous acute cholestatic symptoms, in fact, suggests more aggressive systemic diseases such as non Hodgkin's lymphomas or acute leukemias. Nevertheless, we observed two cases of mixed cellularity H.L. showing all the symptoms of acute cholestatic hepatitis, without systemic lymph nodes involvement. Diagnosis was achieved by liver biopsy. Hepatic histology showed extensive portal and periportal Hodgkin's infiltrations, loss of periportal liver cells and variable damage to small bile ducts. In both cases bone marrow biopsy showed granulomatous infiltrations. Liver failure appeared to be the most frequent terminal complication of cholestatic H.L. The course of the disease was rapid, and cytostatic therapy scarcely effective. In our opinion, the cholestatic variety of H.L. should be considered in the differential diagnosis of all cases of acute or chronic cholestatic hepatitis, irrespectively of the presence of systemic lymph nodes enlargement.