RESUMEN

Proliferative verrucous leukoplakia (PVL) is a particularly aggressive form of oral leukoplakia that is resistant to treatment and presents a high risk of recurrence and malignant transformation. This article describes the microscopic and clinical characteristics of one case of PVL, which initially presented as hyperkeratosis with mild dysplasia and posteriorly developed multifocal areas and verrucous carcinoma despite treatment.

Asunto(s)

Leucoplasia Bucal/patología , Carcinoma Verrugoso/patología , Transformación Celular Neoplásica/patología , Estudios de Seguimiento , Humanos , Queratosis/patología , Masculino , Persona de Mediana Edad , Suelo de la Boca/patología , Mucosa Bucal/patología , Neoplasias de la Boca/patología , Recurrencia Local de Neoplasia , Factores de Riesgo , Neoplasias de la Lengua/patología