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Gravity simulators1 are laboratory systems in which small excitations such as sound2 or surface waves3,4 behave as fields propagating on a curved spacetime geometry. The analogy between gravity and fluids requires vanishing viscosity2-4, a feature naturally realized in superfluids such as liquid helium or cold atomic clouds5-8. Such systems have been successful in verifying key predictions of quantum field theory in curved spacetime7-11. In particular, quantum simulations of rotating curved spacetimes indicative of astrophysical black holes require the realization of an extensive vortex flow12 in superfluid systems. Here we demonstrate that, despite the inherent instability of multiply quantized vortices13,14, a stationary giant quantum vortex can be stabilized in superfluid 4He. Its compact core carries thousands of circulation quanta, prevailing over current limitations in other physical systems such as magnons5, atomic clouds6,7 and polaritons15,16. We introduce a minimally invasive way to characterize the vortex flow17,18 by exploiting the interaction of micrometre-scale waves on the superfluid interface with the background velocity field. Intricate wave-vortex interactions, including the detection of bound states and distinctive analogue black hole ringdown signatures, have been observed. These results open new avenues to explore quantum-to-classical vortex transitions and use superfluid helium as a finite-temperature quantum field theory simulator for rotating curved spacetimes19.
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We present the complete genome sequence of the probiotic strain Lactobacillus acidophilus ATCC 9224. The genome sequence provides a valuable resource for investigating the phylogenetic evolution of this lineage and conducting comparative genomics with other Lactobacillus strains and species.
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Quasinormal modes (QNMs) are essential for understanding the stability and resonances of open systems, with increasing prominence in black hole physics. We present here the first study of QNMs of optical potentials. We show that solitons can support QNMs, deriving a soliton perturbation equation and giving exact analytical expressions for the QNMs of fiber solitons. We discuss the boundary conditions in this intrinsically dispersive system and identify novel signatures of dispersion. From here, we discover a new analogy with black holes and describe a regime in which the soliton is a robust black hole simulator for light-ring phenomena. Our results invite a range of applications, from the description of optical pulse propagation with QNMs to the use of state-of-the-art technology from fiber optics to address questions in black hole physics, such as QNM spectral instabilities and the role of nonlinearities in ringdown.
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Analogue models of gravity, particularly fluid mechanical analogues, have been very successful in mimicking the behavior of fields around black holes. However, hydrodynamic black holes are externally driven systems whose effective mass and angular momentum are set by experimental parameters, and, as such, no appreciable internal backreaction is expected to take place. On the contrary, we show using a rotating draining vortex flow that a fluid system of finite size responds to the presence of waves on timescales much longer than the wave dynamics, which leads to a significant global change in the total mass of our system. This backreaction is encapsulated by a dynamical metric, raising the possibility of studying backreaction in analogue black hole spacetimes.
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The late stages of the relaxation process of a black hole are expected to depend only on its mass and angular momentum and not on the details of its formation process. Inspired by recent analogue gravity experiments, which demonstrate that certain black hole processes take place in gravitational and hydrodynamical systems alike, we conduct an experiment to search for quasinormal mode oscillations of the free surface of a hydrodynamical vortex flow. Our results demonstrate the occurrence and hint at the ubiquity of quasinormal ringing in nonequilibrium analog black hole experiments.
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Background: Acute Coronary Syndrome (ACS) is a leading cause of morbidity and mortality. Perturbed gut- microbiota (dysbiosis) and increased intestinal permeability (leaky-gut) with translocation of bacterial antigens, play critical role in obesity and metabolic syndrome, which are also major ACS risk factors. Additionally, Trimethylamine-N-Oxide (TMAO), a metabolite produced by phylum Proteobacteria in gut is implicated in developing ACS. As Proteobacteria is a major source of translocated antigen lipopolysaccharides (LPS), we hypothesized that ACS patients have leaky-gut condition characterized by dysbiosis with increased Proteobacteria, leading to elevated blood levels of TMAO and LPS. Methods: In a pilot case-control study, we enrolled 19 ACS patients (within 72-h of cardiac events) and 19 healthy-controls. Gut barrier function was determined using lactulose-to-mannitol urinary excretion ratio (L/M ratio). Stool microbiome composition was examined using16S sequencing and predictive functional analysis for LPS biosynthesis pathway by PICRUSt tool. Serum TMAO and LPS levels were measured. Results: ACS patients had increased Gammaproteobacteria compared to controls:1.8 ±3.0 vs. 0.2 ±0.4% (P =0.04). Though Proteobacteria level was increased but not statistically significant: 4.1 ±3.8 vs. 2.1 ±1.7% (P =0.056). L/M-ratio was three times higher in ACS patients; 0.06 ±0.07 vs 0.023 ±0.02, (P =0.014). Surprisingly, there was no difference in the mean serum LPS or TMAO levels. However, PICRUSt analysis indicated increased Proteobacteria population increasingly contributed to LPS biosynthesis in ACS patients only. Conclusions: ACS patients likely to have leaky-gut and perturbed gut microbiota. Further studies are required to precisely define the role of dysbiosis in ACS.
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Clostridioides (Clostridium) difficile is a spore-forming anaerobic bacterium that causes severe intestinal diseases in humans. Here, we report the complete genome sequence of the first C. difficile foodborne type strain (PCR ribotype 078) isolated from food animals in Canada in 2004, which has 100% similarity to the genome sequence of the historic human clinical strain M120.
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Quasinormal modes are a set of damped resonances that describe how an excited open system is driven back to equilibrium. In gravitational physics these modes characterize the ringdown of a perturbed black hole, e.g., following a binary black hole merger. A careful analysis of the ringdown spectrum reveals the properties of the black hole, such as its angular momentum and mass. In more complex gravitational systems, the spectrum might depend on more parameters and hence allows us to search for new physics. We present a hydrodynamic analog of a rotating black hole that illustrates how the presence of extra structure affects the quasinormal mode spectrum. The analogy is obtained by considering wave scattering on a draining bathtub vortex flow. We show that due to vorticity of the background flow, the resulting field theory corresponds to a scalar field on an effective curved spacetime which acquires a local mass in the vortex core. The obtained quasinormal mode spectrum exhibits long-lived trapped modes, commonly known as quasibound states. Our findings can be tested in future experiments building upon recent successful implementations of analog rotating black holes.