RESUMEN
For 2 years, a systematic research of paracoccidioidomycosis (PCM) had been conducted in a hospital in the city of Corrientes. The inclusion criterium used was: tuberculosis patients (TBC), presumptive or confirmed diagnosis of pulmonary cancer (CA), chronic obstructive pulmonary disease (COPD) and/or X-ray images compatible with pulmonary mycosis (XRC). Eighty four patients were studied: 57 (TBC), 1 (CA), 5 (COPD), 3 (TBC+CA), 4 (TBC+COPD), 4 (COPD+CA) and 10 (XRC). Serology tests by agar gel immunodiffusion (IDGA) were performed on all patients, whereas microbiological studies were performed on those cases in which clinical samples could be obtained. Ten PCM were diagnosed by IDGA; 4 associated to TBC, 1 to TBC+CA, 3 to COPD and only 2 to XRC. PCM was mycologically proven in 9 of these cases. Systematic research of PCM would lead to an early diagnosis and therefore, to better chances for a successful treatment.
Asunto(s)
Enfermedades Endémicas/estadística & datos numéricos , Enfermedades Pulmonares/epidemiología , Paracoccidioidomicosis/epidemiología , Adulto , Anciano , Alcoholismo/epidemiología , Argentina/epidemiología , Comorbilidad , Hospitales Especializados/estadística & datos numéricos , Humanos , Enfermedades Pulmonares Fúngicas/diagnóstico por imagen , Enfermedades Pulmonares Fúngicas/epidemiología , Neoplasias Pulmonares/epidemiología , Persona de Mediana Edad , Enfermedad Pulmonar Obstructiva Crónica/epidemiología , Radiografía , Factores de Riesgo , Población Rural , Fumar/epidemiología , Factores Socioeconómicos , Tuberculosis/epidemiologíaRESUMEN
Se realizó la búsqueda sistemática de paracoccidioidomicosis (PCM) en un conjunto de pacientes que fueron atendidos en un hospital de la ciudad de Corrientes dentro de un período de dos años. El criterio de inclusión fue: pacientes con tuberculosis (TBC), pacientes con diagnóstico presuntivo o confirmado de cáncer de pulmón (CA), pacientes con enfermedad pulmonar obstructiva crónica (EPOC) y pacientes con imagen radiológica compatible con micosis pulmonar (IRXC). Se estudiaron 84 pacientes: 57 con TBC, 1 con CA, 5 con EPOC, 3 con TBC+CA, 4 con TBC+EPOC, 4 con EPOC+CA y 10 con IRXC. A todos se les realizó serología por inmunodifusión en gel de agar (IDGA) y, en los casos en que se pudo obtener una muestra clínica, también se efectuaron estudios microbiológicos. Por IDGA se diagnosticaron 10 casos de PCM: 4 asociados a TBC, 1 a TBC+CA, 3 a EPOC y 2 a IRXC; 9 de ellos se corroboraron por el hallazgo del hongo. La búsqueda sistemática de PCM en habitantes del área endémica que presentan patología pulmonar favorecería el diagnóstico precoz y, por lo tanto, las posibilidades de un tratamiento eficaz.
For 2 years, a systematic research of paracoccidioidomycosis (PCM) had been conducted in a hospital in the city of Corrientes. The inclusion criterium used was: tuberculosis patients (TBC), presumptive or confirmed diagnosis of pulmonary cancer (CA), chronic obstructive pulmonary disease (COPD) and/or X-ray images compatible with pulmonary mycosis (XRC). Eighty four patients were studied: 57 (TBC), 1 (CA), 5 (COPD), 3 (TBC+CA), 4 (TBC+COPD), 4 (COPD+CA) and 10 (XRC). Serology tests by agar gel immunodiffusion (IDGA) were performed on all patients, whereas microbiological studies were performed on those cases in which clinical samples could be obtained. Ten PCM were diagnosed by IDGA; 4 associated to TBC, 1 to TBC+CA, 3 to COPD and only 2 to XRC. PCM was mycologically proven in 9 of these cases. Systematic research of PCM would lead to an early diagnosis and therefore, to better chances for a successful treatment.
Asunto(s)
Adulto , Anciano , Humanos , Persona de Mediana Edad , Enfermedades Endémicas/estadística & datos numéricos , Enfermedades Pulmonares/epidemiología , Paracoccidioidomicosis/epidemiología , Alcoholismo/epidemiología , Argentina/epidemiología , Comorbilidad , Hospitales Especializados/estadística & datos numéricos , Enfermedades Pulmonares Fúngicas/epidemiología , Enfermedades Pulmonares Fúngicas , Neoplasias Pulmonares/epidemiología , Enfermedad Pulmonar Obstructiva Crónica/epidemiología , Factores de Riesgo , Población Rural , Factores Socioeconómicos , Fumar/epidemiología , Tuberculosis/epidemiologíaRESUMEN
In the present work was studied the prevalence, distribution in clinical specimens, and antimicrobial susceptibility of non-fermentative Gram-negative bacilli (NFGNB) from patients attended at Hospital "Angela I. de Llano" (Corrientes, Argentina). A total of 125 strains of NFGNB were recovered from various clinical specimens from July, 1997 to December, 1998. Isolates were identified by classical biochemical tests. Drug sensitivity was performed by standard methods with cefotaxime (CTX), ceftazidime (CAZ), piperacillin (PIP), ampicillin-sulbactam (AMS), piperacillin/tazobactam (TAZ), imipenem (IMP), amikacin (AKN), gentamicin (GEN) and ciprofloxacin (CIP). The most common isolates were Pseudomonas aeruginosa (48.8%); Acinetobacter baumannii (16.8%), Acinetobacter spp. (6.4%), Chryseobacterium spp. (5.6%), Stenotrophomonas maltophilia (4%), and others (18.4%). Most of them were recovered from respiratory secretions (36.0%), and urine (26.4%). IMP was the most effective antimicrobial. Many species of NFGNB showed resistance to several antibiotics tested (CTX, GEN, AMS, and CIP). Due to multiresistance found by more prevalent NFGNB, constant survey of antibacterial sensibility are essential for a correct control and management of nosocomial infections, and ambulatory patients with some risk factors.