RESUMEN

A significant association with asymptomatic joint hypermobility was observed in 37 children with a history of infantile hypertrophic pyloric stenosis (P =.0016) and their parents (mothers, P <.0001; fathers, P <.05). The subjects with articular hypermobility showed an increased frequency of absent mandibular frenulum, thereby suggesting the presence of a previously unrecognized, systemic abnormality of the extracellular matrix.

Asunto(s)

Inestabilidad de la Articulación/complicaciones , Estenosis Pilórica/complicaciones , Matriz Extracelular/patología , Femenino , Humanos , Lactante , Inestabilidad de la Articulación/diagnóstico , Masculino , Estenosis Pilórica/patología , Estenosis Pilórica/cirugía

RESUMEN

Among 25 patients with hypertrophic pyloric stenosis, a hypoplastic or absent mandibular frenulum was noted in 92%, compared with 1.6% of 319 control infants (P <.001). This previously unrecognized sign may prove helpful in identifying newborns at risk of developing the disorder.

Asunto(s)

Frenillo Labial/anomalías , Estenosis Pilórica/complicaciones , Femenino , Humanos , Hipertrofia , Recién Nacido , Masculino , Estenosis Pilórica/patología