RESUMEN
A morbidity level of workers in chemical industry depends on labour conditions, anthropometric dates and harmful habits. As informative signs of health state are 2-6 indices of humoral and cellular immunity. The age, social state and life duration in this town are less informative for health state.
Asunto(s)
Industria Química , Monitoreo del Ambiente , Morbilidad , Exposición Profesional , Salud Laboral , Estado de Salud , HumanosRESUMEN
Comparison of the official and research data on congenital developmental defects frequency (CDDF) in children of Novomoskovsk showed their disagreement. The average CDDF in these children is not more than the Middle European level. Physical development of children is insufficient for their biological age in 25% of cases. Many children suffer from respiratory diseases because of ambient air pollution. The majority of children (88-93%) are referred to 2-4 th health groups according to WHO classification.
Asunto(s)
Discapacidades del Desarrollo/epidemiología , Exposición a Riesgos Ambientales , Estado de Salud , Mortalidad Infantil , Efectos Tardíos de la Exposición Prenatal , Adolescente , Niño , Discapacidades del Desarrollo/etiología , Discapacidades del Desarrollo/fisiopatología , Femenino , Humanos , Incidencia , Lactante , Recién Nacido , Embarazo , Federación de Rusia/epidemiologíaRESUMEN
Three variants of psoriatic nephropathy are distinguished on the basis of light microscopical and immunohistochemical study of 23 cases/20 kidney biopsies and 3 autopsy cases/: glomerulonephritis, amyloidosis and minimal kidney alterations. Chronic glomerulonephritis is mainly of a mesangioproliferative type with fixation of IgA and C3 on the mesangium and basal membranes of glomerular capillaries. Psoriatic amyloidosis has morphologically, all the features of acquired amyloidosis/AA-amyloidosis/. Thus psoriatic nephropathy is a reflection of a disturbed homeostasis.
Asunto(s)
Enfermedades Renales/patología , Psoriasis/patología , Adolescente , Adulto , Anciano , Amiloidosis/etiología , Amiloidosis/metabolismo , Amiloidosis/patología , Biopsia , Complemento C3/metabolismo , Femenino , Glomerulonefritis/etiología , Glomerulonefritis/metabolismo , Glomerulonefritis/patología , Humanos , Inmunoglobulinas/metabolismo , Inmunohistoquímica , Riñón/metabolismo , Riñón/patología , Enfermedades Renales/etiología , Enfermedades Renales/metabolismo , Masculino , Persona de Mediana Edad , Psoriasis/complicaciones , Psoriasis/metabolismoRESUMEN
Based on studying the data obtained during examination of patients with psoriasis combined with the urinary syndrome possible varieties of psoriatic nephropathy, namely chronic glomerulonephritis (CGN) and amyloidosis were distinguished. CGN combined with psoriasis was mainly represented by latent glomerulonephritis (GN) and morphologically, it was mostly represented by the mesangio-proliferative variant, with IgA and C3 being fixed on the basal membrane of the capillaries and in the mesangium. The clinicomorphological feature of that form of psoriatic GN is combination of the signs of both associated CGN and hyperuricemia and IgA-nephritis. Special emphasis is laid on the diagnosis of rapid-progressing GN which is of paramount importance for institution of early etiopathogenetic therapy. Amyloidosis associated with psoriasis is characterized by the signs of acquired disease (AA-amyloidosis) and does not differ in its course from amyloidosis coupled with other diseases.