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1.
Skin Res Technol ; 30(7): e13835, 2024 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-39023837

RESUMEN

INTRODUCTION: The search for minimally invasive treatments for areas not covered by clothing, such as the arms, has increased, particularly to combat flaccidity resulting from factors such as aging and weight loss. This study evaluated the efficacy of calcium hydroxyapatite (CaHA), an injectable biostimulator, in improving flaccidity and hydration of the skin of the arms. MATERIALS AND METHODS: Six women between 40 and 50 years old with visible signs of brachial flaccidity were selected. Calcium hydroxyapatite was injected into the arms in a 1:4 dilution (1.5 mL per side), with subjective evaluation based on the GAIS score and objective hydration analysis using corneometry. RESULTS: After a single application of CaHA, there was a significant increase in skin hydration (12.2%), objectively assessed by corneometry. Patient and physician satisfaction was high, evidenced by visible improvements in photographs and by the GAIS score. No significant adverse events were reported, demonstrating the safety of the procedure. DISCUSSION: Our clinical observations confirm the ability of CaHA to visibly improve arm flaccidity. In addition, hydration measures support previous histological studies demonstrating increases in dermal proteoglycans. Compared to other studies, the increase in skin hydration with CaHA was similar to those obtained with hyaluronic acid, suggesting comparable results with a more comfortable and less invasive technique. CONCLUSION: This study demonstrates the efficacy of CaHA in improving hydration of brachial skin after a single treatment. Despite the limitations of the sample size, the research contributes to the medical literature, highlighting the utility of the 3 mL CaHA presentation for brachial treatment with objective results in skin hydration.


Asunto(s)
Durapatita , Envejecimiento de la Piel , Humanos , Femenino , Durapatita/administración & dosificación , Persona de Mediana Edad , Adulto , Envejecimiento de la Piel/efectos de los fármacos , Brazo , Piel/efectos de los fármacos , Piel/patología , Satisfacción del Paciente , Técnicas Cosméticas , Materiales Biocompatibles/administración & dosificación
2.
Clin Cosmet Investig Dermatol ; 16: 2781-2791, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37823019

RESUMEN

Introduction: There are several therapeutic modalities for neck rejuvenation, especially calcium hydroxylapatite. Botulinum toxin, by relaxing the mm. platysma, also provides improvement in facial contour. Combination treatments for this region are usually recommended as they offer better results. Objective: This study evaluated the efficacy and safety of the joint dilution of both products (Relax and Firmness - RF), applied in the same device, based on the treatment in the topography of the platysma muscle, ie, starting from the lower third of the face and extending to the neck. Methods: Prospective, blinded, controlled study with 10 participants randomly assigned to RF and 5 in the control group (treated with CaHA only). Results were recorded through the Vectra platform and subjectively evaluated through the GAIS scale by participants and blinded evaluators. Objective analysis was performed using corneometry. Times evaluated: pre-treatment, 30 and 90 days. Considered statistically significant when p<0.1. Results: 100% of the RF group reported "excellent improvement" at D30 and 30% at D90. In the control group, 100% reported "very improved" at D30 and 20% rated "excellent improvement" at D90. A higher and earlier satisfaction rate was observed in the RF group. No difference in corneometry was found between the groups at D30. At D90, the control group had a mean increase of 0.24 versus 5.17 in the RF group (p-value=0.089*). When we analyzed the percentage variation from baseline, the control group was stable, while the RF showed a mean increase of 8.89% (p-value=0.062*). Discussion: We demonstrated the safety and effectiveness of the association of both products, diluted and applied together through microcannulas. Minimization of punctures, patient comfort, and technique based on the anatomy of the platysma muscle underlie the technique. High rates of early satisfaction due to botulinum toxin (Relaxation) and late satisfaction due to CaHA (Firmness).

3.
Surg. cosmet. dermatol. (Impr.) ; 12(4 S1): 124-127, fev.-nov. 2020.
Artículo en Portugués | LILACS-Express | LILACS | ID: biblio-1367528

RESUMEN

Rinofima é uma doença desfigurante e progressiva do nariz, com alta prevalência. Apesar de ser considerada benigna, muitos pacientes têm procurado tratamentos curativos devido a deformidade estética e estigmatização social. Existem diversas técnicas cirúrgicas descritas para o tratamento desta doença. O objetivo deste relato é apresentar um caso que necessitou de abordagem terapêutica pouco utilizada para tratamento de rinofima devido às múltiplas comorbidades do paciente. O procedimento foi realizado sem complicações no intra e pós-operatório, e o paciente mantém seguimento ambulatorial com bom resultado estético final a longo prazo


Rhinophyma is a disfiguring and progressive disease of the nose with high prevalence. Despite being considered a benign condition, many patients have sought curative treatments due to aesthetic deformity and social stigmatization. There are several surgical techniques described in the treatment of this disease. This report aims to present a case that required an unusual therapeutic approach for the treatment of rhinophyma, given the patient's multiple comorbidities. The procedure was performed with no complications in the intra and postoperative period. The patient maintains an outpatient follow-up with a good long-term aesthetic result

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